Sebaceoma of the External Auditory Canal
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Sebaceomas of the external auditory canal (EAC) are extremely rare. The recognition of sebaceomais important as this benign tumor can be be part of the spectrum of the Muir-Torre syndrome(MTS), which is associated with visceral malignancy and multiple adenomatous polyps. Proper histological identification is thus important for further investigation. We describea rare case of a sebaceoma that was confined to the EAC. Subsequent immunohistochemical(IHC) staining analysis of the mismatch repair genes (MLH1, MSH2, MSH6, and PMS2) wasneeded to investigate MTS. Even though the patient has had the history of colon cancer, theresult was negative. Otorhinolaryngologists should be aware of rare sebaceoma and its potentialassociation with the internal malignancy, besides the limitation of IHC screening test.
Abstract
Sebaceomas of the external auditory canal (EAC) are extremely rare. The recognition of sebaceomais important as this benign tumor can be be part of the spectrum of the Muir-Torre syndrome(MTS), which is associated with visceral malignancy and multiple adenomatous polyps. Proper histological identification is thus important for further investigation. We describea rare case of a sebaceoma that was confined to the EAC. Subsequent immunohistochemical(IHC) staining analysis of the mismatch repair genes (MLH1, MSH2, MSH6, and PMS2) wasneeded to investigate MTS. Even though the patient has had the history of colon cancer, theresult was negative. Otorhinolaryngologists should be aware of rare sebaceoma and its potentialassociation with the internal malignancy, besides the limitation of IHC screening test.
참고문헌 (15)
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