Deoxypodophyllotoxin Inhibits Cell Growth and Induces Apoptosis by Blocking EGFR and MET in Gefitinib-Resistant Non-Small Cell Lung Cancer

키워드

참고문헌 (34)

1. Chang CH, "The safety and efficacy of gefitinib versus platinum-based doublets chemotherapy as the first-line treatment for advanced non-small-cell lung cancer patients in East Asia : a meta-analysis", Lung Cancer, 62, pp.242~252 (2008)
2. Li Y, "Biochanin A Induces S phase arrest and apoptosis in lung cancer cells", Biomed. Res. Int, 2018, pp.3545376~ (2018)
3. Zeng X, "Economic outcomes of maintenance gefitinib for locally advanced", metastatic non-small-cell lung cancer with unknown EGFR mutations : a semi-Markov model analysis, 2014, pp.9, e88881~
4. Liu G, "Role of autophagy and apoptosis in non-small-cell lung cancer", Int. J. Mol. Sci, 18, pp.367~ (2017)
5. Wang C, "Inhibition of lung cancer proliferation by wogonin is associated with activation of apoptosis and generation of reactive oxygen species", Balkan Med. J, 37, pp.29~33 (2019)
6. Kawata T, "Gefitinib exposure and occurrence of interstitial lung disease in Japanese patients with non-small-cell lung cancer", Cancer Chemother. Pharmacol, 83, pp.849~858 (2019)
7. Kitagawa C, "Gefitinib plus bevacizumab vs. gefitinib alone for EGFR mutant non-squamous non-small cell lung cancer", In Vivo, 33, pp.477~482 (2019)
8. Leonetti A, "Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer", Br. J. Cancer, 121, pp.725~737 (2019)
9. Ping W, "MiR-181a contributes gefitinib resistance in non-small cell lung cancer cells by targeting GAS7", Biochem. Biophys. Res. Commun, 495, pp.2482~2489 (2018)
10. Shin SY, "Deoxypodophyllotoxin induces G2", M cell cycle arrest and apoptosis in HeLa cells, 2010, pp.287, 231~239
11. Park BR, "Anthricininduced caspasedependent apoptosis through IGF1R", PI3K, Oncol. Rep, pp.2018, 39[DOI]
12. Wang W, "Deoxypodophyllotoxin inhibits cell viability and invasion by blocking the PI3K", Akt signaling pathway in human glioblastoma cells, 2019, pp.41, 2453~2463
13. Yang L, "Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells : therapeutic effect of a novel polyarginine-conjugated Smac peptide", Cancer Res, 63, pp.831~837 (2003)
14. Li YC, "Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K", Akt, Cancer Lett, pp.2014, 344[DOI]
15. Lee MH, "Menadione induces G2", M arrest in gastric cancer cells by downregulation of CDC25C and proteasome mediated degradation of CDK1 and cyclin B1, 2016, pp.8, 5246~5255
16. Lin F, "Inhibition of casein kinase 2 blocks G2", M transition in early embryo mitosis but not in oocyte meiosis in mouse, 2017, pp.63, 319~324
17. Shen X, "Induction of G2", M phase arrest and apoptosis by ZGDHU-1 in A549 and RERF-LC-MA lung cancer cells, 2016, pp.12, 989~994
18. 김은애, "Isolation, Semisynthesis, and Molecular Modeling of Deoxypodophyllotoxin Analogs for an Anti-oral Cancer Agent", Bulletin of the Korean Chemical Society, 41(4), pp.472~475 (2020), 대한화학회[DOI]
19. Engelman JA, "MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling", Science, 316, pp.1039~1043 (2007)
20. Oh HN, "Licochalcone B inhibits growth and induces apoptosis of human nonsmall-cell lung cancer cells by dual targeting of EGFR and MET", Phytomedicine, 63, pp.153014~ (2019)
21. Arulananda S, "Combination osimertinib and gefitinib in C797S and T790M EGFR-Mutated non-small cell lung cancer", J. Thorac. Oncol, 12, pp.1728~1732 (2017)
22. Xiang Y, "Traditional Chinese medicine as a cancer treatment : Modern perspectives of ancient but advanced science", Cancer Med, 8, pp.1958~1975 (2019)
23. Yi YW, "Dual inhibition of EGFR and MET induces synthetic lethality in triple-negative breast cancer cells through downregulation of ribosomal protein S6", Int. J. Oncol, 47, pp.122~132 (2015)
24. Surya Kant Tripathi, "Plumbagin engenders apoptosis in lung cancer cells via caspase-9 activation and targeting mitochondrial-mediated ROS induction", Archives of Pharmacal Research, 43(2), pp.242~256 (2020), 대한약학회[DOI]
25. Khaw-On P, "Apoptosis induction via ATM phosphorylation, cell cycle arrest, and ER stress by goniothalamin and chemodrugs combined effects on breast cancer-derived MDA-MB-231 cells", Biomed. Res. Int, 2018, pp.7049053~ (2018)
26. Mao XM, "Diosgenin suppresses cholangiocarcinoma cells via inducing cell cycle arrest and mitochondria-mediated apoptosis", Onco. Targets Ther, 12, pp.9093~9104 (2019)
27. Yang KM, "omega-Hydroxyundec-9-enoic acid induces apoptosis through ROS-mediated endoplasmic reticulum stress in non-small cell lung cancer cells", Biochem. Biophys. Res. Commun, 448, pp.267~273 (2014)
28. Zheng YZ, "The endoplasmic reticulum stress markers GRP78 and CHOP predict disease-free survival and responsiveness to chemotherapy in breast cancer", Breast Cancer Res. Treat, 145, pp.349~358 (2014)
29. Tungjai M, , Presented at the 2015 4th International Conference on Instrumentation, Communications, Information Technology, and Biomedical Engineering (ICICI-BME) (2015)
30. Wang YR, "Deoxypodophyllotoxin induces G2", M cell cycle arrest and apoptosis in SGC-7901 cells and inhibits tumor growth in vivo, 2015, pp.20, 1661~1675
31. Wu M, "Deoxypodophyllotoxin triggers necroptosis in human non-small cell lung cancer NCI-H460 cells", Biomed. Pharmacother, 67, pp.701~706 (2013)
32. Guerram M, "Antineoplastic effects of deoxypodophyllotoxin, a potent cytotoxic agent of plant origin, on glioblastoma U-87 MG and SF126 cells", Pharmacol. Rep, 67, pp.245~252 (2015)
33. Chen Y, "Predicting antitumor effect of deoxypodophyllotoxin in NCI-H460 rumorbearing mice on the basis of In Vitro pharmacodynamics and a physiologically based pharmacokinetic-pharmacodynamic model", Drug Metab. Dispos, 46, pp.897~907 (2018)
34. Yang Y, "Validated LC-MS", MS assay for quantitative determination of deoxypodophyllotoxin in rat plasma and its application in pharmacokinetic study, 2014, pp.88, 410~415

관련 논문AI추천