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태아발육제한 처치의 최신지견

NEW ASPECT IN MANAGEMENT OF FETAL GROWTH RESTRICTION

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참고문헌

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주제분류산부인과학

초록

태아발육제한은 가장 흔하고 복잡한 질환 중 하나로서 주산기 이환율과 사망률의 증가와 연관이 있으며, 신생아 및 그 자손의 건강에도장기적인 영향을 미친다. 태아발육제한에서의 산과적 처치의 목적은 발육이 제한되고 중증의 자궁 내 저산소증의 위험에 처해있는 태아를발견하고, 적절히 감시하여 유해한 결과가 발생하기 전에 분만시키는 것이다. 본 종설에서는 태아발육제한의 진단, 산전 감시 및 임상적처치에 대하여 알아보고자 한다.

Abstract

Fetal growth restriction (FGR) is one of the most common and complex diseases and it is associated with increased perinatal mortality and morbidity. FGR influences the long-term health of neonates and their offspring. The aim of obstetric management is to identify growth-restricted fetuses at risk of severe intrauterine hypoxia, to monitor their health and to deliver when the adverse outcome is imminent. This review aims to investigate the new aspects of FGR including the diagnosis, antenatal surveillance, and clinical management.

참고문헌 (83)

  1. Ounsted M, "Perinatal morbidity and mortality in small-for-dates babies: the relative importance of some maternal factors", Early Hum Dev, 5, pp.367~375 (1981)
  2. smussen S, "A history of placental dysfunction and risk of placental abruption", Paediatr Perinat Epidemiol, 13, pp.9~21 (1999)
  3. Zhang J, "Defining normal and abnormal fetal growth: promises and challenges", Am J Obstet Gynecol, 202, pp.522~528 (2010)
  4. Lindqvist PG, "Does antenatal identification of smallfor-gestational age fetuses significantly improve their outcome", Ultrasound Obstet Gynecol, 25, pp.258~264 (2005)
  5. Mahsud-Dornan S, "IUGR: a contemporary review", Best Pract Res Clin Obstet Gynaecol, 23, pp.739~740 (2009)
  6. Wisser J, "Estimation of gestational age by transvaginal sonographic measurement of greatest embryonic length in dated human embryos", Ultrasound Obstet Gynecol, 4, pp.457~462 (1994)
  7. Ott WJ, "Sonographic diagnosis of fetal growth restriction", Clin Obstet Gynecol, 49, pp.295~307 (2006)
  8. Jones TB, "Biparietal diameter and femur length discrepancies: are maternal characteristics important", Ultrasound Obstet Gynecol, 1, pp.405~409 (1991)
  9. Shepard MJ, "An evaluation of two equations for predicting fetal weight by ultrasound", Am J Obstet Gynecol, 142, pp.47~54 (1982)
  10. Hadlock FP, "Sonographic estimation of fetal weight. The value of femur length in addition to head and abdomen measurements", Radiology, 150, pp.535~540 (1984)
  11. Bobrow CS, "Fetal growth velocity: a cautionary tale", Lancet, 353, pp.1460~ (1999)
  12. Smith GC, "The relation between fetal abdominal circumference and birthweight: findings in 3512 pregnancies", Br J Obstet Gynaecol, 104, pp.186~190 (1997)
  13. Abramowicz JS, "Incorporating sonographic cheek-to-cheek diameter, biparietal diameter and bdominal circumference improves weight estimation in the macrosomic fetus", Ultrasound Obstet Gynecol, 9, pp.409~413 (1997)
  14. Gardeil F, "Subcutaneous fat in the fetal abdomen as a predictor of growth restriction", Obstet Gynecol, 94, pp.209~212 (1999)
  15. Larciprete G, "Could birthweight prediction models be improved by adding fetal subcutaneous tissue thickness", J Obstet Gynaecol Res, 34, pp.18~26 (2008)
  16. Mintz MC, "Shoulder soft tissue width as a predictor of macrosomia in diabetic pregnancies", Am J Perinatol, 6, pp.240~243 (1989)
  17. Sood AK, "Prediction of fetal macrosomia using humeral soft tissue thickness", Obstet Gynecol, 85, pp.937~940 (1995)
  18. Lee W, "New fetal weight estimation models using fractional limb volume", Ultrasound Obstet Gynecol, 34, pp.556~565 (2009)
  19. Lee W, "Birthweight prediction by three-dimensional ultrasonographic volumes of the fetal thigh and abdomen", J Ultrasound Med, 16, pp.799~805 (1997)
  20. Song TB, "Fetal weight prediction by thigh volume measurement with three-dimensional ultrasonography", Obstet Gynecol, 96, pp.157~161 (2000)
  21. Lubchenco LO, "Intrauterine Growth as Estimated from Liveborn Birth-Weight Data at 24 to 42 Weeks of Gestation", Pediatrics, 32, pp.793~800 (1963)
  22. Baschat AA, "Umbilical artery doppler screening for detection of the small fetus in need of antepartum surveillance", Am J Obstet Gynecol, 182, pp.154~158 (2000)
  23. Ott WJ, "Intrauterine growth restriction and Doppler ultrasonography", J Ultrasound Med, 19, pp.661~665 (2000)
  24. Baschat AA, "Integrated fetal testing in growth restriction: combining multivessel Doppler and biophysical parameters", Ultrasound Obstet Gynecol, 21, pp.1~8 (2003)
  25. Ott WJ, "Diagnosis of intrauterine growth restriction: comparison of ultrasound parameters", Am J Perinatol, 19, pp.133~137 (2002)
  26. Baschat AA, "Fetal growth restriction due to placental disease", Semin Perinatol, 28, pp.67~80 (2004)
  27. Salafia CM, "Intrauterine growth restriction in infants of less than thirty-two weeks' gestation: associated placental pathologic features", Am J Obstet Gynecol, 173, pp.1049~1057 (1995)
  28. Baschat AA, "The sequence of changes in Doppler and biophysical parameters as severe fetal growth restriction worsens", Ultrasound Obstet Gynecol, 18, pp.571~577 (2001)
  29. Harman CR, "Comprehensive assessment of fetal wellbeing: which Doppler tests should be performed", Curr Opin Obstet Gynecol, 15, pp.147~157 (2003)
  30. Bukowski R, "Individualized norms of optimal fetal growth: fetal growth potential", Obstet Gynecol, 111, pp.1065~1076 (2008)
  31. Gagnon A, "Obstetrical complications associated with abnormal maternal serum markers analytes", J Obstet Gynaecol Can, 30, pp.918~949 (2008)
  32. Maulik D, "Fetal growth restriction: pathogenic mechanisms", Clin Obstet Gynecol, 49, pp.219~227 (2006)
  33. Chaiworapongsa T, "The maternal plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated in SGA and the magnitude of the increase relates to Doppler abnormalities in the maternal and fetal circulation", JOURNAL OF MATERNAL-FETAL NEONATAL MEDICINE, 21(1), pp.25~40 (2008), TAYLOR FRANCIS LTD
  34. Crispi F, "Placental angiogenic growth factors and uterine artery Doppler findings for characterization of different subsets in preeclampsia and in isolated intrauterine growth restriction", Am J Obstet Gynecol, 195, pp.201~207 (2006)
  35. Romero R, "A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate", J Matern Fetal Neonatal Med, 21, pp.9~23 (2008)
  36. Dunger DB, "Genetic variations and normal fetal growth", Horm Res, 65(3), pp.34~40 (2006)
  37. Kaku K, "Insulin-like growth factor 2 (IGF2) and IGF2 receptor gene variants are associated with fetal growth", Acta Paediatr, 96, pp.363~367 (2007)
  38. Baschat AA, "Fetal growth restriction-from observation to intervention", J Perinat Med, 38, pp.239~246 (2010)
  39. FitzGerald DE, "Non-invasive measurement of human fetal circulation using ultrasound: a new method", Br Med J, 2, pp.1450~1451 (1977)
  40. Trudinger BJ, "Fetal umbilical artery flow velocity waveforms and placental resistance: clinical significance", Br J Obstet Gynaecol, 92, pp.23~30 (1985)
  41. Karsdorp VH, "Clinical significance of absent or reversed end diastolic velocity waveforms in umbilical artery", Lancet, 344, pp.1664~1668 (1994)
  42. Brodszki J, "Can the degree of retrograde diastolic flow in abnormal umbilical artery flow velocity waveforms predict pregnancy outcome", Ultrasound Obstet Gynecol, 19, pp.229~234 (2002)
  43. Thornton JG, "Infant wellbeing at 2 years of age in the Growth Restriction Intervention Trial (GRIT): multicentred randomised controlled trial", Lancet, 364, pp.513~520 (2004)
  44. Alfirevic Z, "oppler ultrasound for fetal assessment in high risk pregnancies. Cochrane Database Syst Rev 2010;(1):CD000073", ~ (2010)
  45. Goffinet F, "Umbilical artery Doppler velocimetry in unselected and low risk pregnancies: a review of randomised controlled trials", Br J Obstet Gynaecol, 104, pp.425~430 (1997)
  46. Harrington K, "Doppler ultrasound of the uterine arteries: the importance of bilateral notching in the prediction of pre-eclampsia, placental abruption or delivery of a small-for-gestational-age baby", Ultrasound Obstet Gynecol, 7, pp.182~188 (1996)
  47. Bricker L, "Routine doppler ultrasound in pregnancy. Cochrane Database Syst Rev 2000;(2):CD001450", ~ (2000)
  48. Vergani P, "Prognostic value of uterine artery Doppler velocimetry in growth-restricted fetuses delivered near term", Am J Obstet Gynecol, 187:, pp.932~936 (2002)
  49. Sebire NJ, "Umbilical artery Doppler revisited: pathophysiology of changes in intrauterine growth restriction revealed", pp.419~422 (2003), Ultrasound Obstet Gynecol
  50. Mari G, "Doppler ultrasonography in obstetrics: from the diagnosis of fetal anemia to the treatment of intrauterine growth-restricted fetuses", Am J Obstet Gynecol, 200통권 : 613, pp.1~9 (2009)
  51. Hershkovitz R, "Fetal cerebral blood flow redistribution in late gestation: identification of compromise in small fetuses with normal umbilical artery Doppler", Ultrasound Obstet Gynecol, 15, pp.209~212 (2000)
  52. Severi FM, "Uterine and fetal cerebral Doppler predict the outcome of third-trimester small-for-gestational age fetuses with normal umbilical artery Doppler", Ultrasound Obstet Gynecol, 19, pp.225~228 (2002)
  53. To WW, "Use of umbilical-cerebral Doppler ratios in predicting fetal growth restriction in near-term fetuses", Aust N Z J Obstet Gynaecol, 45, pp.130~136 (2005)
  54. Scherjon SA, "Neurodevelopmental outcome at three years of age after fetal 'brain-sparing", Early Hum Dev, 52, pp.67~79 (1998)
  55. Cruz-Martinez R, "Cerebral blood perfusion and neurobehavioral performance in full-term small-for-gestational-age fetuses", Am J Obstet Gynecol, 201, pp.1~7 (2009)
  56. Eixarch E, "Neurodevelopmental outcome in 2-year-old infants who were small-for-gestational age term fetuses with cerebral blood flow redistribution", Ultrasound Obstet Gynecol, 32, pp.894~899 (2008)
  57. Borrell A, "Abnormal ductus venosus blood flow in trisomy 21 fetuses during early pregnancy", Am J Obstet Gynecol, 179, pp.1612~1617 (1998)
  58. Baschat AA, "Qualitative venous Doppler waveform analysis improves prediction of critical perinatal outcomes in premature growth-restricted fetuses", Ultrasound Obstet Gynecol, 22, pp.240~245 (2003)
  59. Schwarze A, "Qualitative venous Doppler flow waveform analysis in preterm intrauterine growth-restricted fetuses with ARED flow in the umbilical artery-correlation with short-term outcome", Ultrasound Obstet Gynecol, 25, pp.573~579 (2005)
  60. Hecher K, "Monitoring of fetuses with intrauterine growth restriction: a longitudinal study", Ultrasound Obstet Gynecol, 18, pp.564~570 (2001)
  61. Ferrazzi E, "Temporal sequence of abnormal Doppler changes in the peripheral and central circulatory systems of the severely growth-restricted fetus", Ultrasound Obstet Gynecol, 19, pp.140~146 (2002)
  62. Makikallio K, "Ultrasonographic and biochemical markers of human fetal cardiac dysfunction in placental insufficiency", Circulation, 105, pp.2058~2063 (2002)
  63. Rizzo G, "Doppler echocardiographic assessment of fetal cardiac function", Ultrasound Obstet Gynecol, 2, pp.434~445 (1992)
  64. Rizzo G, "Ventricular ejection force in growth-retarded fetuses", Ultrasound Obstet Gynecol, 5, pp.247~255 (1995)
  65. Cruz-Martinez R, "Sequence of changes in myocardial performance index in relation with aortic isthmus and ductus venosus Doppler in fetuses with early-onset intrauterine growth restriction", Ultrasound Obstet Gynecol (2010)[DOI]
  66. Turan OM, "Progression of Doppler abnormalities in intrauterine growth restriction", Ultrasound Obstet Gynecol, 32, pp.160~167 (2008)
  67. Phelan JP, "Amniotic fluid index measurements during pregnancy", J Reprod Med, 32, pp.601~604 (1987)
  68. Chauhan SP, "Perinatal outcome and amniotic fluid index in the antepartum and intrapartum periods: A meta-analysis", Am J Obstet Gynecol, 181, pp.1473~1478 (1999)
  69. Gulmezoglu AM, "Bed rest in hospital for suspected impaired fetal growth. Cochrane Database Syst Rev 2000;(2):CD000034", ~ (2000)
  70. Say L, "Maternal nutrient supplementation for suspected impaired fetal growth. Cochrane Database Syst Rev 2003;(1):CD000148", ~ (2003)
  71. "Maternal oxygen administration for suspected impaired fetal growth. Cochrane Database Syst Rev 2003;(1):CD000137", ~ (2003)
  72. Gulmezoglu AM, "Calcium channel blockers for potential impaired fetal growth. Cochrane Database Syst Rev 2000;(2):CD000049", ~ (2000)
  73. Bernstein IM, "Morbidity and mortality among very-low-birth-weight neonates with intrauterine growth restriction. The Vermont Oxford Network", Am J Obstet Gynecol, 182, pp.198~206 (2000)
  74. Baschat AA, "Predictors of neonatal outcome in early-onset placental dysfunction", Obstet Gynecol, 109, pp.253~261 (2007)
  75. Brodszki J, "Early intervention in management of very preterm growthrestricted fetuses: 2-year outcome of infants delivered on fetal indication before 30 gestational weeks", Ultrasound Obstet Gynecol, 34, pp.288~296 (2009)
  76. Marsal K, "Obstetric management of intrauterine growth restriction", Best Pract Res Clin Obstet Gynaecol, 23, pp.857~870 (2009)
  77. Froen JF, "Restricted fetal growth in sudden intrauterine unexplained death", Acta Obstet Gynecol Scand, 83, pp.801~807 (2004)
  78. Baschat AA, "Natural history of stillbirth in placenta based fetal growth restriction-implications for surveillance. Annual Meeting of the Society for Maternal-Fetal Medicine", Am J Obstet Gynecol, 199, pp.S198~ (2008)
  79. Bahado-Singh RO, "The Doppler cerebroplacental ratio and perinatal outcome in intrauterine growth restriction", Am J Obstet Gynecol, 180, pp.750~756 (1999)
  80. Hecher K, "Potential for diagnosing imminent risk to appropriate- and small-for-gestational-age fetuses by Doppler sonographic examination of umbilical and cerebral arterial blood flow", Ultrasound Obstet Gynecol, 2, pp.266~271 (1992)
  81. Kaukola T, "Suboptimal neurodevelopment in very preterm infants is related to fetal cardiovascular compromise in placental insufficiency", Am J Obstet Gynecol, 193, pp.414~420 (2005)
  82. Baschat AA, "Infant neurodevelopment following fetal growth restriction: relationship with antepartum surveillance parameters", Ultrasound Obstet Gynecol, 33, pp.44~50 (2009)
  83. Roza SJ, "What is spared by fetal brain-sparing? Fetal circulatory redistribution and behavioral problems in the general population", Am J Epidemiol, 168, pp.1145~1152 (2008)

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