Challenging management of chorioamnionitis with placental listeriosis: lessons from 2 cases
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Listeriosis is a rare foodborne infection caused by Listeria monocytogenes. It is 12–20 times more prevalent in pregnant women compared to the general population, with a 20–40% mortality rate in neonates. Early treatment with propriate ntimicrobial agents is critical for pregnancy outcomes; however, the infection is difficult tocontrol because the nonspecific clinical manifestations and rarity of the disease often preclude early diagnosis. Weencountered 2 cases of pregnancy-associated listeriosis that occurred at 29 and 37 weeks of gestation. Both neonateswere delivered by emergent cesarean section due to fetal condition, and one of the preterm infants died immediatelyafter birth. Pregnancy-associated listeriosis should be considered in the management of unexplained fever orinflammatory conditions in pregnant women.
Abstract
Listeriosis is a rare foodborne infection caused by Listeria monocytogenes. It is 12–20 times more prevalent in pregnant women compared to the general population, with a 20–40% mortality rate in neonates. Early treatment with propriate ntimicrobial agents is critical for pregnancy outcomes; however, the infection is difficult tocontrol because the nonspecific clinical manifestations and rarity of the disease often preclude early diagnosis. Weencountered 2 cases of pregnancy-associated listeriosis that occurred at 29 and 37 weeks of gestation. Both neonateswere delivered by emergent cesarean section due to fetal condition, and one of the preterm infants died immediatelyafter birth. Pregnancy-associated listeriosis should be considered in the management of unexplained fever orinflammatory conditions in pregnant women.
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