본문 바로가기
KERD
논문KCI 등재

Antihyperglycemic agent therapy for adult patients with type 2 diabetes mellitus 2017: a position statement of the Korean Diabetes Association

2

조회

0

다운로드

3

인용

0

참고문헌

키워드

주제분류내과학

초록

In 2017, the Korean Diabetes Association (KDA) published a position statement on the use of antihyperglycemic agents for patients with type 2 diabetes mellitus (T2DM). The KDA regularly updates its Clinical Practice Guidelines, but since the last update in 2015, many results from clinical trials have been introduced, and domestic data from studies performed in Korean patients with T2DM have been published. Recently, evidence from large clinical studies assessing cardiovascular outcomes following the use of sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 receptor agonists in patients with T2DM were incorporated into the recommendations. Additionally, new data from clinical trials using dipeptidyl peptidase 4 inhibitors and thiazolidinediones in Korean patients with T2DM were added. Following a systematic review and assessment of recent evidence, the KDA updated and modified its clinical practice recommendations regarding the use of antihyperglycemic agents and revised the treatment algorithm for Korean adult patients with T2DM.

Abstract

In 2017, the Korean Diabetes Association (KDA) published a position statement on the use of antihyperglycemic agents for patients with type 2 diabetes mellitus (T2DM). The KDA regularly updates its Clinical Practice Guidelines, but since the last update in 2015, many results from clinical trials have been introduced, and domestic data from studies performed in Korean patients with T2DM have been published. Recently, evidence from large clinical studies assessing cardiovascular outcomes following the use of sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 receptor agonists in patients with T2DM were incorporated into the recommendations. Additionally, new data from clinical trials using dipeptidyl peptidase 4 inhibitors and thiazolidinediones in Korean patients with T2DM were added. Following a systematic review and assessment of recent evidence, the KDA updated and modified its clinical practice recommendations regarding the use of antihyperglycemic agents and revised the treatment algorithm for Korean adult patients with T2DM.

참고문헌 (57)

  1. 고승현, "2011 Clinical Practice Guidelines for Type 2 Diabetes in Korea", Diabetes and Metabolism Journal, 35(5), pp.431~436 (2011), 대한당뇨병학회
  2. 민경완, "Addition of Ipragliflozin to Metformin Treatment in Korean Patients with Type 2 Diabetes Mellitus: Subgroup Analysis of a Phase 3 Trial", Diabetes and Metabolism Journal, 41(2), pp.135~145 (2017), 대한당뇨병학회[DOI]
  3. 김종호, "Comparison of Vildagliptin and Pioglitazone in Korean Patients with Type 2 Diabetes Inadequately Controlled with Metformin", Diabetes and Metabolism Journal, 40(3), pp.230~239 (2016), 대한당뇨병학회[DOI]
  4. Yoon KH, "Efficacy and safety of empagliflozin in patients with type 2 diabetes from Asian countries: pooled data from four phase III trials", Diabetes Obes Metab, 18, pp.1045~1049 (2016)
  5. 윤건호, "Exenatide versus Insulin Lispro Added to Basal Insulin in a Subgroup of Korean Patients with Type 2 Diabetes Mellitus", Diabetes and Metabolism Journal, 41(1), pp.69~74 (2017), 대한당뇨병학회[DOI]
  6. American Diabetes Association., "Standards of medical care in diabetes: 2017", Diabetes Care, 40(Suppl 1), pp.S1~S135 (2017)
  7. UK Prospective Diabetes Study (UKPDS) Group., "Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)", Lancet, 352, pp.837~853 (1998)
  8. Garber AJ, "Consensus statement by the American association of clinical endocrinologists and American college of endocrinology on the comprehensive type 2 diabetes management algorithm:2017 executive summary", Endocr Pract, 23, pp.207~238 (2017)
  9. McGuire H, "Management of type 2diabetes in adults: summary of updated NICE guidance", BMJ, 353, pp.i1575~ (2016)
  10. Inzucchi SE, "Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes", Diabetes Care, 38, pp.140~149 (2015)
  11. 김정민, "Factors Associated with Participation in Diabetes Education: The Korea National Health and Nutrition Examination Survey 2007 to 2009", Diabetes and Metabolism Journal, 40(6), pp.447~453 (2016), 대한당뇨병학회[DOI]
  12. 용윤미, "Intensive Individualized Reinforcement Education Is Important for the Prevention of Hypoglycemia in Patients with Type 2 Diabetes", Diabetes and Metabolism Journal, 39(2), pp.154~163 (2015), 대한당뇨병학회
  13. Kyoung Hwa Ha, "Current status of managing diabetes mellitus in Korea", The Korean Journal of Internal Medicine, 31(5), pp.845~850 (2016), 대한내과학회[DOI]
  14. 전숙, "An Update on the Effect of Incretin-Based Therapies on β-Cell Function and Mass", Diabetes and Metabolism Journal, 40(2), pp.99~114 (2016), 대한당뇨병학회[DOI]
  15. Turner RC, "Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49)", JAMA, 281, pp.2005~2012 (1999), UK Prospective Diabetes Study (UKPDS) Group
  16. Sherifali D, "The effect of oral antidiabetic agents on A1C levels: a systematic review and meta-analysis", Diabetes Care, 33, pp.1859~1864 (2010)
  17. UK Prospective Diabetes Study (UKPDS) Group., "Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)", Lancet, 352, pp.854~865 (1998)
  18. Maruthur NM, "Diabetes medications as monotherapy or metformin-based combination therapy for type 2 diabetes: a systematic review and meta-analysis", Ann Intern Med, 164, pp.740~751 (2016)
  19. Palmer SC, "Comparison of clinical outcomes and adverse events associated with glucose-lowering drugs in patients with type 2 diabetes: a meta-analysis", JAMA, 316, pp.313~324 (2016)
  20. Esposito K, "Glycaemic durability with dipeptidyl peptidase-4 inhibitors in type 2 diabetes: a systematic review and meta-analysis of long-term randomised controlled trials", BMJ Open, 4, pp.e005442~ (2014)
  21. Storgaard H, "Benefits and harms of sodium-glucose co-transporter 2 inhibitors in patients with type 2 diabetes: a systematic review and meta-analysis", PLoS One, 11, pp.e0166125~ (2016)
  22. 윤재승, "Risk Factors and Adverse Outcomes of Severe Hypoglycemia in Type 2 Diabetes Mellitus", Diabetes and Metabolism Journal, 40(6), pp.423~432 (2016), 대한당뇨병학회[DOI]
  23. 차선아, "Severe Hypoglycemia and Cardiovascular or All-Cause Mortality in Patients with Type 2 Diabetes", Diabetes and Metabolism Journal, 40(3), pp.202~210 (2016), 대한당뇨병학회[DOI]
  24. 윤건호, "Comparison of the Efficacy of Glimepiride, Metformin, and Rosiglitazone Monotherapy in Korean Drug-Naïve Type 2 Diabetic Patients: The Practical Evidence of Antidiabetic Monotherapy Study", Diabetes and Metabolism Journal, 35(1), pp.26~33 (2011), 대한당뇨병학회
  25. Foroutan N, "Safety and efficacy of dipeptidyl peptidase-4 inhibitors vs sulfonylurea in metformin-based combination therapy for type 2 diabetes mellitus: systematic review and meta-analysis", Clin Invest Med, 39, pp.E48~E62 (2016)
  26. Zhong X, "Efficacy and safety of empagliflozin as add-on to metformin for type 2 diabetes: a systematic review and meta-analysis", Eur J Clin Pharmacol, 72, pp.655~663 (2016)
  27. Mishriky BM, "The efficacy and safety of DPP4 inhibitors compared to sulfonylureas as add-on therapy to metformin in patients with type 2diabetes: a systematic review and meta-analysis", Diabetes Res Clin Pract, 109, pp.378~388 (2015)
  28. Zhou JB, "The benefits and risks of DPP4-inhibitors vs. sulfonylureas for patients with type 2 diabetes: accumulated evidence from randomised controlled trial", Int J Clin Pract, 70, pp.132~141 (2016)
  29. Del Prato S, "Long-term glycaemic response and tolerability of dapagliflozin versus a sulphonylurea as add-on therapy to metformin in patients with type 2 diabetes: 4-year data", Diabetes Obes Metab, 17, pp.581~590 (2015)
  30. Kim YG, "Differences in the glucose-lowering efficacy of dipeptidyl peptidase-4 inhibitors between Asians and non-Asians:a systematic review and meta-analysis", Diabetologia, 56, pp.696~708 (2013)
  31. Mearns ES, "Efficacy and safety of antihyperglycaemic drug regimens added to metformin and sulphonylurea therapy in type 2 diabetes:a network meta-analysis", Diabet Med, 32, pp.1530~1540 (2015)
  32. Taylor SI, "SGLT2 inhibitors may predispose to ketoacidosis", J Clin Endocrinol Metab, 100, pp.2849~2852 (2015)
  33. 오승준, "The Role of Glucagon-Like Peptide-1 Receptor Agonists in Type 2 Diabetes: Understanding How Data Can Inform Clinical Practice in Korea", Diabetes and Metabolism Journal, 39(3), pp.177~187 (2015), 대한당뇨병학회[DOI]
  34. Kim MK, "Nateglinide and acarbose for postprandial glucose control after optimizing fasting glucose with insulin glargine in patients with type 2 diabetes", Diabetes Res Clin Pract, 92, pp.322~328 (2011)
  35. Olansky L, "A treatment strategy implementing combination therapy with sitagliptin and metformin results in superior glycaemic control versus metformin monotherapy due to a low rate of addition of antihyperglycaemic agents", Diabetes Obes Metab, 13, pp.841~849 (2011)
  36. Phung OJ, "Early combination therapy for the treatment of type 2 diabetes mellitus: systematic review and meta-analysis", Diabetes Obes Metab, 16, pp.410~417 (2014)
  37. Varvaki Rados D, "The association between sulfonylurea use and all-cause and cardiovascular mortality: a meta-analysis with trial sequential analysis of randomized clinical trials", PLoS Med, 13, pp.e1001992~ (2016)
  38. Marso SP, "Liraglutide and cardiovascular outcomes in type 2 diabetes", N Engl J Med, 375, pp.311~322 (2016)
  39. Zinman B, "Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes", N Engl J Med, 373, pp.2117~2128 (2015)
  40. Hwang YC, "The glycemic efficacies of insulin analogue regimens according to baseline glycemic status in Korean patients with type 2 diabetes:sub-analysis from the A(1)chieve(R) study", Int J Clin Pract, 68, pp.1338~1344 (2014)
  41. Malmberg K, "Glycometabolic state at admission: important risk marker of mortality in conventionally treated patients with diabetes mellitus and acute myocardial infarction: long-term results from the Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) study", Circulation, 99, pp.2626~2632 (1999)
  42. Griesdale DE, "Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data", CMAJ, 180, pp.821~827 (2009)
  43. Fonseca V, "An analysis of early insulin glargine added to metformin with or without sulfonylurea:impact on glycaemic control and hypoglycaemia", Diabetes Obes Metab, 13, pp.814~822 (2011)
  44. Park CY, "Comparison between the therapeutic effect of metformin, glimepiride and their combination as an add-on treatment to insulin glargine in uncontrolled patients with type 2 diabetes", PLoS One, 9, pp.e87799~ (2014)
  45. Zhong X, "Effects of three injectable antidiabetic agents on glycaemic control, weight change and drop-out in type 2 diabetes suboptimally controlled with metformin and", or a sulfonylurea: a network meta-analysis, 2015, pp.109, 451~460
  46. Horvath K, "Long-acting insulin analogues versus NPH insulin (human isophane insulin)for type 2 diabetes mellitus", Cochrane Database Syst Rev, (2), pp.CD005613~ (2007)
  47. Russell-Jones D, "Insulin degludec results in lower rates of nocturnal hypoglycaemia and fasting plasma glucose vs. insulin glargine: a meta-analysis of seven clinical trials", Nutr Metab Cardiovasc Dis, 25, pp.898~905 (2015)
  48. Marso SP, "Efficacy and safety of degludec versus glargine in type 2 diabetes", N Engl J Med, 377, pp.723~732 (2017)
  49. Yki-Jarvinen H, "Effects of adding linagliptin to basal insulin regimen for inadequately controlled type 2 diabetes: a ≥52-week randomized, double-blind study", Diabetes Care, 36, pp.3875~3881 (2013)
  50. Kothny W, "Improved glycaemic control with vildagliptin added to insulin, with or without metformin, in patients with type 2 diabetes mellitus", Diabetes Obes Metab, 15, pp.252~257 (2013)
  51. Hong ES, "Comparison between sitagliptin as add-on therapy to insulin and insulin dose-increase therapy in uncontrolled Korean type 2 diabetes:CSI study", Diabetes Obes Metab, 14, pp.795~802 (2012)
  52. Min SH, "Comparison between SGLT2 inhibitors and DPP4 inhibitors added to insulin therapy in type 2 diabetes: a systematic review with indirect comparison meta-analysis", Diabetes Metab Res Rev, 33, pp.e2818~ (2017)
  53. Giugliano D, "Intensification of insulin therapy with basal-bolus or premixed insulin regimens in type 2 diabetes:a systematic review and meta-analysis of randomized controlled trials", Endocrine, 51, pp.417~428 (2016)
  54. Diamant M, "Glucagon-like peptide 1 receptor agonist or bolus insulin with optimized basal insulin in type 2 diabetes", Diabetes Care, 37, pp.2763~2773 (2014)
  55. Eng C, "Glucagon-like peptide-1 receptor agonist and basal insulin combination treatment for the management of type 2diabetes: a systematic review and meta-analysis", Lancet, 384, pp.2228~2234 (2014)
  56. Mathieu C, "A comparison of adding liraglutide versus a single daily dose of insulin aspart to insulin degludec in subjects with type 2 diabetes (BEGIN: VICTOZA ADD-ON)", Diabetes Obes Metab, 16, pp.636~644 (2014)
  57. 최성희, "Comparison of Antidiabetic Regimens in Patients with Type 2 Diabetes Uncontrolled by Combination Therapy of Sulfonylurea and Metformin: Results of the MOHAS Disease Registry in Korea", Diabetes and Metabolism Journal, 41(3), pp.170~178 (2017), 대한당뇨병학회[DOI]

관련 논문AI추천

Insulin therapy for adult patients with type 2 diabetes mellitus: a position statement of the Korean Diabetes Association, 2017고승현, 김난희, 김진화, 김현진, 문민경, 박석오, 이병완, 이상열, 최경묵, 허규연, the Committee of Clinical Practice Guideline of KDA대한내과학회 · The Korean Journal of Internal Medicine2017 · 제32권 제6호Combination therapy of oral hypoglycemic agents in patients with type 2 diabetes mellitus고승현, 김난희, 김진화, 김현진, 문민경, 박석오, 이병완, 이상열, 최경묵, 허규연, the Committee of Clinical Practice Guideline of KDA대한내과학회 · The Korean Journal of Internal Medicine2017 · 제32권 제6호제2형 당뇨병 환자에서 Metformin과 병용한 Sodium-Glucose Cotransporter 2 Inhibitors와 Dipeptidyl Peptidase 4 Inhibitors의 효능 비교권은영, 권지은, 박소연, 유다혜, 윤정이, 황보신이한국병원약사회 · 병원약사회지2020 · 제37권 제3호Lipid Management in Korean People With Type 2 Diabetes Mellitus: Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement김상현, 김학령, 문민경, 양예슬한국지질동맥경화학회 · 지질·동맥경화학회지2023 · 제12권 제1호Monotherapy in patients with type 2 diabetes mellitus고승현, 김난희, 김진화, 김현진, 문민경, 박석오, 이병완, 이상열, 최경묵, 허규연, the Committee of Clinical Practice Guideline of KDA대한내과학회 · The Korean Journal of Internal Medicine2017 · 제32권 제6호Effect of Dapagliflozin in Combination with Lobeglitazone and Metformin in Korean Patients with Type 2 Diabetes in Real-World Clinical Practice김소헌, 서다혜, 서성하, 서영주, 안성희, 이용호, 이은직, 조용인, 최영주, 홍성빈연세대학교의과대학 · Yonsei Medical Journal2022 · 제63권 제9호

이 간행물의 다른 논문 (27건)