Acral Metastasis in a Patient with Ampullary Carcinoma
3
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Although skin metastasis from a malignant tumor of an internal organ usually occurs at an advanced disease stage, there has been no prior report of a cutaneous acral metastasis from ampullary carcinoma to date. We report a 71-year old male patient with cutaneous metastasis from an ampullary adenocarcinoma. The patient had a history of pylorus preserving pancreaticoduodenectomy for carcinoma of the ampulla of Vater two years prior to presentation. Physical examination revealed ill-defined, painful and hard erythematous nodules at the left thumb and distal phalanx of the right middle finger. The computed tomography scan showed low density masses in the retroperitoneum; the histological examination of a nodule from the right middle finger showed a metastatic adenocarcinoma. This case illustrates that cutaneous metastasis from ampullary carcinoma has a poor prognosis.
Abstract
Although skin metastasis from a malignant tumor of an internal organ usually occurs at an advanced disease stage, there has been no prior report of a cutaneous acral metastasis from ampullary carcinoma to date. We report a 71-year old male patient with cutaneous metastasis from an ampullary adenocarcinoma. The patient had a history of pylorus preserving pancreaticoduodenectomy for carcinoma of the ampulla of Vater two years prior to presentation. Physical examination revealed ill-defined, painful and hard erythematous nodules at the left thumb and distal phalanx of the right middle finger. The computed tomography scan showed low density masses in the retroperitoneum; the histological examination of a nodule from the right middle finger showed a metastatic adenocarcinoma. This case illustrates that cutaneous metastasis from ampullary carcinoma has a poor prognosis.
참고문헌 (14)
- "Cutaneous metastases from internal carcinoma", pp.162~168 (1966)
- "Skin metastases in cancer patients", pp.119~39 121 (1987)
- "Cutaneous metastases in patients with metastatic carcinoma a retrospective study of 4020 patients", pp.228~236 (1993)
- "Patterns of cutaneous metastasis", pp.862~868 (1972)
- Takeuchi H, "Cutaneous metastasis from pancreatic adenocarcinoma: a case report and a review of the literature", 20, pp.275~277 (2003)
- Saeed S, "Cutaneous metastasis: a clinical, pathological, and immunohistochemical appraisal", 31, pp.419~430 (2004)
- Stein RH, "Painful cutaneous metastases from esophageal carcinoma", 70, pp.230~232 (2002)
- Howe JR, "Factors predictive of survival in ampullary carcinoma", 228, pp.87~94 (1998)
- Todoroki T, "Patterns and predictors of failure after curative resections of carcinoma of the ampulla of Vater", 10, pp.1176~1183 (2003)
- Le Pessot F, "Cytokeratins 7 and 20 immunohistochemistry in ampullary carcinomas", 24, pp.312~318 (2004)
- Zhou H, "Carcinoma of the ampulla of Vater: comparative histologic", immunohistochemical classification and follow-up, 2004, pp.28, 875~882
- Chu PG, "Immunohistochemical staining in the diagnosis of pancreatobiliary and ampulla of Vater adenocarcinoma: application of CDX2, CK17, MUC1, and MUC2", 29, pp.359~367 (2005)
- Braverman IM, "Skin manifestations of internal malignancy", 18, pp.1~19 (2002)
- DiSpaltro FX, "Cutaneous acral metastasis in a patient with primary gastric adenocarcinoma", pp.117~118 (1992)