Albumin for End-Stage Liver Disease
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초록
Albumin has been widely used in patients with cirrhosis in an attempt to improve circulatory and renal functions. The benefits of albumin infusions in preventing the deterioration in renal function associated with large-volume paracentesis,spontaneous bacterial peritonitis, and established hepatorenal syndrome in conjunction with a vasoconstrictor are well established. While some of these indications are supported by the results of randomized studies, others are based only on clinical experience and have not been proved in prospective studies. The paucity of well-designed trials, the high cost of albumin, the lack of a clear-cut survival benefit, and fear of transmitting unknown infections make the use of albumin controversial. The recent development of the molecular adsorbent recirculating system, an albumin dialysis,is an example of the capacity of albumin to act by mechanisms other than its oncotic effect. Efforts should be made to define the indications for albumin use, the dose required, and predictors of response, so that patients gain the maximum benefit from its administration.
Abstract
Albumin has been widely used in patients with cirrhosis in an attempt to improve circulatory and renal functions. The benefits of albumin infusions in preventing the deterioration in renal function associated with large-volume paracentesis,spontaneous bacterial peritonitis, and established hepatorenal syndrome in conjunction with a vasoconstrictor are well established. While some of these indications are supported by the results of randomized studies, others are based only on clinical experience and have not been proved in prospective studies. The paucity of well-designed trials, the high cost of albumin, the lack of a clear-cut survival benefit, and fear of transmitting unknown infections make the use of albumin controversial. The recent development of the molecular adsorbent recirculating system, an albumin dialysis,is an example of the capacity of albumin to act by mechanisms other than its oncotic effect. Efforts should be made to define the indications for albumin use, the dose required, and predictors of response, so that patients gain the maximum benefit from its administration.
참고문헌 (43)
- Gines P, "Is there still a need for albumin infusions to treat patients with liver disease?", Gut, 46, pp.588~590 (2000)
- Rena NM, "Albumin infusion in liver cirrhotic patients", Acta Med Indones, 42, pp.162~168 (2010)
- "Human albumin administration in critically ill patients: systematic review of randomised controlled trials. Cochrane Injuries Group Albumin Reviewers", BMJ, 317, pp.235~240 (1998)
- Kragh-Hansen U, "Practical aspects of the ligand-binding and enzymatic properties of human serum albumin", Biol Pharm Bull, 25, pp.695~704 (2002)
- Evans TW, "Review article: albumin as a drug-biological effects of albumin unrelated to oncotic pressure", Aliment Pharmacol Ther, 16(Suppl 5), pp.6~11 (2002)
- Wong F, "Drug insight: the role of albumin in the management of chronic liver disease", Nat Clin Pract Gastroenterol Hepatol, 4, pp.43~51 (2007)
- Quinlan GJ, "Administration of albumin to patients with sepsis syndrome: a possible beneficial role in plasma thiol repletion", Clin Sci, 95, pp.459~465 (1998)
- Quinlan GJ, "Albumin: biochemical properties and therapeutic potential", Hepatology, 41, pp.1211~1219 (2005)
- Martin PY, "Nitric oxide as a mediator of hemodynamic abnormalities and sodium and water retention in cirrhosis", N Engl J Med, 339, pp.533~541 (1998)
- Bosch J, "The splanchnic circulation in cirrhosis, In Ascites and renal dysfunction in liver disease: pathogenesis, diagnosis and treatment", pp.330~350 (1999), Blackwell Science
- Arroyo V, "Review article: albumin in the treatment of liver diseases- new features of a classical treatment", Aliment Pharmacol Ther, 16(Suppl 5), pp.1~5 (2002)
- Mendez CM, "Albumin therapy in clinical practice", Nutr Clin Pract, 20, pp.314~320 (2005)
- Soni N, "Albumin, where are we now?", Curr Anaesth Crit Care, 15, pp.61~68 (2004)
- Finfer S, "A comparison of albumin and saline for fluid resuscitation in the intensive care unit", N Engl J Med, 350, pp.2247~2256 (2004)
- Wilkes MM, "Patient survival after human albumin administration: a meta-analysis of randomized, controlled trials", Ann Intern Med, 135, pp.149~164 (2001)
- Laub R, "Parvoviruses and blood products", Pathol Biol, 50, pp.339~348 (2002)
- Laffi G, "Is the use of albumin of value in the treatment of ascites in cirrhosis? The case in favour", Dig Liver Dis, 35, pp.660~663 (2003)
- Gentilini P, "Albumin improves the response to diuretics in patients with cirrhosis and ascites: results of a randomized, controlled trial", J Hepatol, 30, pp.639~645 (1999)
- Avidan B, "The use of albumin in all patients with decompensated cirrhosis is not justified", Isr Med Assoc J, 7, pp.118~120 (2005)
- Runyon BA, "Historical aspects of treatment of patients with cirrhosis and ascites", Semin Liver Dis, 17, pp.163~173 (1997)
- Gines P, "Randomized comparative study of therapeutic paracentesis with and without intravenous albumin in cirrhosis", Gastroenterology, 94, pp.1493~1502 (1988)
- Gines A, "Randomized trial comparing albumin, dextran 70, and polygeline in cirrhotic patients with ascites treated by paracentesis", Gastroenterology, 111, pp.1002~1010 (1996)
- Peltekian KM, "Cardiovascular, renal, and neurohumoral responses to single large-volume paracentesis in patients with cirrhosis and diuretic-resistant ascites", Am J Gastroenterol, 92, pp.394~399 (1997)
- Runyon BA, "Management of adult patients with ascites caused by cirrhosis", Hepatology, 27, pp.264~272 (1998)
- Follo A, "Renal impairment after spontaneous bacterial peritonitis in cirrhosis: incidence, clinical course, predictive factors and prognosis", Hepatology, 20, pp.1495~1501 (1994)
- Sort P, "Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis", N Engl J Med, 341, pp.403~409 (1999)
- Fernandez J, "A randomized unblinded pilot study comparing albumin versus hydroxyethyl starch in spontaneous bacterial peritonitis", Hepatology, 42, pp.627~634 (2005)
- Haynes GR, "Albumin administrationwhat is the evidence of clinical benefit? A systematic review of randomized controlled trials", Eur J Anaesthesiol, 20, pp.771~793 (2003)
- Faloon WW, "The effect of human serum albumin, mercurial diuretics, and a low sodium diet on sodium excretion in patients with cirrhosis of the liver", J Clin Invest, 28, pp.595~602 (1949)
- McCloy RM, "Effects of changing plasma volume, serum albumin concentration, and plasma osmolality on renal function in cirrhosis", Gastroenterology, 53, pp.229~239 (1967)
- Wong PY, "Studies on the renin-angiotensin-aldosterone system in patients with cirrhosis and ascites: effect of saline and albumin infusion", Gastroenterology, 77, pp.1171~1176 (1979)
- Angeli P, "Cirrhosis and muscle cramps: evidence of a causal relationship", Hepatology, 23, pp.264~273 (1996)
- Bataller R, "Hepatorenal syndrome", Semin Liver Dis, 17, pp.233~247 (1997)
- Guevara M, "Reversibility of hepatorenal syndrome by prolonged administration of ornipressin and plasma volume expansion", Hepatology, 27, pp.35~41 (1998)
- Duvoux C, "Effects of noradrenalin and albumin in patients with type I hepatorenal syndrome: a pilot study", Hepatology, 36, pp.374~380 (2002)
- Ortega R, "Terlipressin therapy with and without albumin for patients with hepatorenal syndrome: results of a prospective, nonrandomized study", Hepatology, 36(4), pp.941~948 (2002)
- Mitzner SR, "Extracorporeal detoxification using the molecular adsorbent recirculating system for critically ill patients with liver failure", J Am Soc Nephrol, 12(Suppl 17), pp.S75~S82 (2001)
- Jalan R, "Improvement in cerebral perfusion after MARS therapy: further clues about the pathogenesis of hepatic encephalopathy?", Liver Transpl, 7, pp.713~715 (2001)
- Mitzner SR, "Improvement of hepatorenal syndrome with extracorporeal albumin dialysis MARS: results of a prospective, randomized, controlled clinical trial", Liver Transpl, 6, pp.277~286 (2000)
- Schmidt LE, "Hemodynamic changes during a single treatment with the molecular adsorbents recirculating system in patients with acute-on-chronic liver failure", Liver Transpl, 7, pp.1034~1039 (2001)
- Sen S, "Pathophysiological effects of albumin dialysis in acute-on-chronic liver failure: a randomized controlled study", Liver Transpl, 10, pp.1109~1119 (2004)
- McCormick PA, "Intravenous albumin infusion is an effective therapy for hyponatraemia in cirrhotic patients with ascites", Gut, 31, pp.204~207 (1990)
- Jalan R, "Reversal of diuretic-induced hepatic encephalopathy with infusion of albumin but not colloid", Clin Sci, 106, pp.467~474 (2004)