Sleep quality in rheumatoid arthritis, and its association with disease activity in a Korean population
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Background/Aims: The aim of this study was to compare the sleep quality between rheumatoid arthritis (RA) patients and healthy controls; and to evaluate the relationship between RA disease activity and sleep quality in Korea. Methods: A total of 130 RA patients and 67 age- and sex-matched healthy controls were enrolled in a comparative study of sleep quality using the Pittsburgh Sleep Quality Index (PSQI). Age, gender, concomitant medication, erythrocyte sedimentation rate, serum C-reactive protein, Beck Depression Inventory second edition (BDI-II), 28 joints disease activity score (DAS28), pain visual analog scale (VAS), and PSQI were analyzed as covariates. We also analyzed the sleep quality of RA patients according to the disease activity (DAS28 ≤ 3.2, 3.2 < DAS28 < 5.1, and DAS28 ≥ 5.1, respectively). Results: The total PSQI score and the frequency of poor sleep quality, were higher in the RA patients (5.62 ± 4.19, 38.5%) than in the control subjects (3.57 ± 2.17, 13.4%). The patients with poor sleep quality (PSQI > 5) were older and had a higher BDI-II and VAS score than the patients without sleep disturbance (PSQI ≤ 5). The score in subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbance, daytime dysfunction, total PSQI, and frequency of poor sleep quality were increased when RA activity was high. Conclusions: Sleep disturbance was observed in RA patients (38.5%), and high RA disease activity was associated with poor sleep quality in Korea.
Abstract
Background/Aims: The aim of this study was to compare the sleep quality between rheumatoid arthritis (RA) patients and healthy controls; and to evaluate the relationship between RA disease activity and sleep quality in Korea. Methods: A total of 130 RA patients and 67 age- and sex-matched healthy controls were enrolled in a comparative study of sleep quality using the Pittsburgh Sleep Quality Index (PSQI). Age, gender, concomitant medication, erythrocyte sedimentation rate, serum C-reactive protein, Beck Depression Inventory second edition (BDI-II), 28 joints disease activity score (DAS28), pain visual analog scale (VAS), and PSQI were analyzed as covariates. We also analyzed the sleep quality of RA patients according to the disease activity (DAS28 ≤ 3.2, 3.2 < DAS28 < 5.1, and DAS28 ≥ 5.1, respectively). Results: The total PSQI score and the frequency of poor sleep quality, were higher in the RA patients (5.62 ± 4.19, 38.5%) than in the control subjects (3.57 ± 2.17, 13.4%). The patients with poor sleep quality (PSQI > 5) were older and had a higher BDI-II and VAS score than the patients without sleep disturbance (PSQI ≤ 5). The score in subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbance, daytime dysfunction, total PSQI, and frequency of poor sleep quality were increased when RA activity was high. Conclusions: Sleep disturbance was observed in RA patients (38.5%), and high RA disease activity was associated with poor sleep quality in Korea.
참고문헌 (27)
- Choy EH, "Cytokine pathways and joint inflammation in rheumatoid arthritis", N Engl J Med, 344, pp.907~916 (2001)
- Luyster FS, "Sleep quality and functional disability in patients with rheumatoid arthritis", J Clin Sleep Med, 7, pp.49~55 (2011)
- Kojima M, "Psychosocial factors, disease status, and quality of life in patients with rheumatoid arthritis", J Psychosom Res, 67, pp.425~431 (2009)
- Sariyildiz MA, "Sleep quality in rheumatoid arthritis: relationship between the disease severity, depression, functional status and the quality of life", J Clin Med Res, 6, pp.44~52 (2014)
- Abad VC, "Sleep and rheumatologic disorders", Sleep Med Rev, 12, pp.211~228 (2008)
- Westhovens R, "Sleep problems in patients with rheumatoid arthritis", J Rheumatol, 41, pp.31~40 (2014)
- Drewes AM., "Pain and sleep disturbances with special reference to fibromyalgia and rheumatoid arthritis", Rheumatology (Oxford), 38, pp.1035~1038 (1999)
- Ulus Y, "Sleep quality in fibromyalgia and rheumatoid arthritis:associations with pain, fatigue, depression, and disease activity", Clin Exp Rheumatol, 29(6 Suppl 69), pp.S92~S96 (2011)
- Nicassio PM, "Confirmatory factor analysis of the Pittsburgh Sleep Quality Index in rheumatoid arthritis patients", Behav Sleep Med, 12, pp.1~12 (2014)
- Wells G, "Responsiveness of patient reported outcomes including fatigue, sleep quality, activity limitation, and quality of life following treatment with abatacept for rheumatoid arthritis", Ann Rheum Dis, 67, pp.260~265 (2008)
- Wells G, "Investigation into the impact of abatacept on sleep quality in patients with rheumatoid arthritis, and the validity of the MOS-Sleep questionnaire Sleep Disturbance Scale", Ann Rheum Dis, 69, pp.1768~1773 (2010)
- Kim KS, "A study on sleep in rheumatoid arthritis patients", J Korean Acad Fundam Nurs, 6, pp.198~210 (1999)
- Oh DH, "Depression and its associated factors with rheumatoid arthritis", J Korean Rheum Assoc, 7, pp.232~242 (2000)
- Arnett FC, "The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis", Arthritis Rheum, 31, pp.315~324 (1988)
- Prevoo ML, "Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis", Arthritis Rheum, 38, pp.44~48 (1995)
- Sohn SI, "The reliability and validity of the Korean version of the Pittsburgh Sleep Quality Index", Sleep Breath, 16, pp.803~812 (2012)
- 성형모, "한국어판 백 우울 설문지 2판의 신뢰도 및 타당도 연구", 생물치료정신의학, 14(2), pp.201~212 (2008), 대한생물치료정신의학회
- Ohayon MM, "Prevalence of insomnia and associated factors in South Korea", J Psychosom Res, 53, pp.593~600 (2002)
- Kushida CA, "Practice parameters for the indications for polysomnography and related procedures: an update for 2005", Sleep, 28, pp.499~521 (2005)
- Smolen JS, "Treating rheumatoid arthritis to target: recommendations of an international task force", Ann Rheum Dis, 69, pp.631~637 (2010)
- Vgontzas AN, "Marked decrease in sleepiness in patients with sleep apnea by etanercept, a tumor necrosis factor-alpha antagonist", J Clin Endocrinol Metab, 89, pp.4409~4413 (2004)
- Zamarron C, "Effect of the first infliximab infusion on sleep and alertness in patients with active rheumatoid arthritis", Ann Rheum Dis, 63, pp.88~90 (2004)
- Fragiadaki K, "Fragiadaki K, Tektonidou MG, Konsta M, Chrousos GP, Sfikakis PP. Sleep disturbances and interleukin 6 receptor inhibition in rheumatoid arthritis", J Rheumatol, 39, pp.60~62 (2012)
- Matcham F, "The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis", Rheumatology (Oxford), 52, pp.2136~2148 (2013)
- Dickens C, "Depression in rheumatoid arthritis: a systematic review of the literature with meta-analysis", Psychosom Med, 64, pp.52~60 (2002)
- Buysse DJ, "The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research", Psychiatry Res, 28, pp.193~213 (1989)
- Wells GA, "Assessing quality of sleep in patients with rheumatoid arthritis", J Rheumatol, 36, pp.2077~2086 (2009)