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Hyponatremia in acute heart failure: a marker of poor condition or a mediator of poor outcome?

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초록

Heart failure is a growing issue around the world; there are currently more than 20 million affected patients. Hospitalization for acute heart failure (AHF) is associated with poor prognosis; the 1-year mortality rate for AHF patients is roughly 10 times that for healthy individuals.

Abstract

Heart failure is a growing issue around the world; there are currently more than 20 million affected patients. Hospitalization for acute heart failure (AHF) is associated with poor prognosis; the 1-year mortality rate for AHF patients is roughly 10 times that for healthy individuals.

참고문헌 (10)

  1. Shahar E, "Hospitalized heart failure: rates and long-term mortality", J Card Fail, 10, pp.374~379 (2004)
  2. Upadhyay A, "Incidence and prevalence of hyponatremia", Am J Med, 119(7 Suppl 1), pp.S30~S35 (2006)
  3. Abraham WT, "Predictors of in-hospital mortality in patients hospitalized for heart failure: insights from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)", J Am Coll Cardiol, 52, pp.347~356 (2008)
  4. Klein L, "Lower serum sodium is associated with increased short-term mortality in hospitalized patients with worsening heart failure:results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) study", Circulation, 111, pp.2454~2460 (2005)
  5. Lee SE, "Improvement of hyponatraemia during hospitalisation for acute heart failure is not associated with improvement of prognosis: an analysis from the Korean Heart Failure (KorHF) registry", Heart, 98, pp.1798~1804 (2012)
  6. Szatalowicz VL, "Radioimmunoassay of plasma arginine vasopressin in hyponatremic patients with congestive heart failure", N Engl J Med, 305, pp.263~266 (1981)
  7. Hoorn EJ, "Hyponatremia and mortality: moving beyond associations", Am J Kidney Dis, 62, pp.139~149 (2013)
  8. Waikar SS, "Mortality associated with low serum sodium concentration in maintenance hemodialysis", Am J Med, 124, pp.77~84 (2011)
  9. Madan VD, "Impact of change in serum sodium concentration on mortality in patients hospitalized with heart failure and hyponatremia", Circ Heart Fail, 4, pp.637~643 (2011)
  10. 유병수, "Prognostic value of hyponatremia in heart failure patients: an analysis of the Clinical Characteristics and Outcomes in the Relation with Serum Sodium Level in Asian Patients Hospitalized for Heart Failure (COAST) study", The Korean Journal of Internal Medicine, 30(4), pp.460~470 (2015), 대한내과학회[DOI]

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