Bone metastasis in pulmonary sclerosing hemangioma
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Pulmonary sclerosing hemangioma is a rare neoplasm of the lungs first described in 1956 [1]. Recent immunohistochemical studies have revealed that these tumors are epithelial in origin and derived from primitive respiratory epithelium, incompletely differentiated type II pneumocytes, or Clara cells [2]. Although composed of mixed cell populations, clonal analysis has shown that these tumors are monoclonal [3]. However, there have been no reports of extrapulmonary metastases from these tumors to date. Herein, we describe a patient with bone metastasis from a pulmonary sclerosing hemangioma.
Abstract
Pulmonary sclerosing hemangioma is a rare neoplasm of the lungs first described in 1956 [1]. Recent immunohistochemical studies have revealed that these tumors are epithelial in origin and derived from primitive respiratory epithelium, incompletely differentiated type II pneumocytes, or Clara cells [2]. Although composed of mixed cell populations, clonal analysis has shown that these tumors are monoclonal [3]. However, there have been no reports of extrapulmonary metastases from these tumors to date. Herein, we describe a patient with bone metastasis from a pulmonary sclerosing hemangioma.
참고문헌 (5)
- Liebow AA, "Sclerosing hemangioma (histiocytoma, xanthoma) of the lung", Cancer, 9, pp.53~75 (1956)
- Devouassoux-Shisheboran M, "A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies: TTF-1 is expressed in both round and surface cells, suggesting an origin from primitive respiratory epithelium", Am J Surg Pathol, 24, pp.906~916 (2000)
- Niho S, "Monoclonality of both pale cells and cuboidal cells of sclerosing hemangioma of the lung", Am J Pathol, 152, pp.1065~1069 (1998)
- Neuman J, "Radiology-pathology conference: sclerosing hemangioma of the lung", Clin Imaging, 30, pp.409~412 (2006)
- Miyagawa-Hayashino A, "Pulmonary sclerosing hemangioma with lymph node metastases: report of 4 cases", Arch Pathol Lab Med, 127, pp.321~325 (2003)