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Heart Rate Variability Among Children With Acquired Brain Injury

김윤|전하라|김성우|김지영
대한재활의학회 (Korean Academy Of Rehabilitation Medicine)|2017.12|Annals of Rehabilitation Medicine|제41권 제6호|pp. 951-960

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참고문헌

키워드

Heart rateAutonomic nervous systemSympathetic nervous systemBrain injuriesParasympathetic nervous system
주제분류재활의학

초록

Objective To find evidence of autonomic imbalance and present the heart rate variability (HRV) parameters that reflect the severity of paroxysmal sympathetic hyperactivity (PSH) in children with acquired brain injury (ABI).Methods Thirteen children with ABI were enrolled and age- and sex-matched children with cerebral palsy were selected as the control group (n=13). The following HRV parameters were calculated: time-domain indices including the mean heart rate, standard deviation of all average R-R intervals (SDNN), root mean square of the successive differences (RMSSD), physical stress index (PSI), approximate entropy (ApEn); successive R-R interval difference (SRD), and frequency domain indices including total power (TP), high frequency (HF), low frequency (LF), normalized HF, normalized LF, and LF/HF ratio.Results There were significant differences between the ABI and control groups in the mean heart rate, RMSSD, PSI and all indices of the frequency domain analysis. The mean heart rate, PSI, normalized LF, and LF/HF ratio increased in the ABI group. The presence of PSH symptoms in the ABI group demonstrated a statistically significant decline of the SDNN, TP, ln TP.Conclusion The differences in the HRV parameters and presence of PSH symptoms are noted among ABI children compared to an age- and sex-matched control group with cerebral palsy. Within the ABI group, the presence of PSH symptoms influenced the parameters of HRV such as SDNN, TP and ln TP.

Abstract

Objective To find evidence of autonomic imbalance and present the heart rate variability (HRV) parameters that reflect the severity of paroxysmal sympathetic hyperactivity (PSH) in children with acquired brain injury (ABI).Methods Thirteen children with ABI were enrolled and age- and sex-matched children with cerebral palsy were selected as the control group (n=13). The following HRV parameters were calculated: time-domain indices including the mean heart rate, standard deviation of all average R-R intervals (SDNN), root mean square of the successive differences (RMSSD), physical stress index (PSI), approximate entropy (ApEn); successive R-R interval difference (SRD), and frequency domain indices including total power (TP), high frequency (HF), low frequency (LF), normalized HF, normalized LF, and LF/HF ratio.Results There were significant differences between the ABI and control groups in the mean heart rate, RMSSD, PSI and all indices of the frequency domain analysis. The mean heart rate, PSI, normalized LF, and LF/HF ratio increased in the ABI group. The presence of PSH symptoms in the ABI group demonstrated a statistically significant decline of the SDNN, TP, ln TP.Conclusion The differences in the HRV parameters and presence of PSH symptoms are noted among ABI children compared to an age- and sex-matched control group with cerebral palsy. Within the ABI group, the presence of PSH symptoms influenced the parameters of HRV such as SDNN, TP and ln TP.

참고문헌 (33)

  1. "Traumatic brain injury in the United States: emergency department visits, hospitalizations, and deaths 2002-2006 (blue book)" (2016)[URL]
  2. Schaller AL, "Pediatric traumatic brain injury", S D Med, 68, pp.457~461 (2015)
  3. DeMatteo CA, "Quality-of-life after brain injury in childhood: time, not severity, is the significant factor", Brain Inj, 28, pp.114~121 (2014)
  4. Baguley IJ, "Pharmacological management of dysautonomia following traumatic brain injury", Brain Inj, 18, pp.409~417 (2004)
  5. Baguley IJ, "Dysautonomia and heart rate variability following severe traumatic brain injury", Brain Inj, 20, pp.437~444 (2006)
  6. Baguley IJ, "The incidence of dysautonomia and its relationship with autonomic arousal following traumatic brain injury", Brain Inj, 21, pp.1175~1181 (2007)
  7. Hendricks HT, "Brain injury severity and autonomic dysregulation accurately predict heterotopic ossification in patients with traumatic brain injury", Clin Rehabil, 21, pp.545~553 (2007)
  8. Baguley IJ, "Dysautonomia after traumatic brain injury: a forgotten syndrome?", J Neurol Neurosurg Psychiatry, 67, pp.39~43 (1999)
  9. Raithel DS, "Morphine: an effective abortive therapy for pediatric paroxysmal sympathetic hyperactivity after hypoxic brain injury", J Pediatr Pharmacol Ther, 20, pp.335~340 (2015)
  10. Israeli-Mendlovic H, "Heart rate and heart rate variability parameters at rest, during activity and passive standing among children with cerebral palsy GMFCS IV-V", Dev Neurorehabil, 17, pp.398~402 (2014)
  11. Scott JS, "Autonomic dysfunction associated with locked-in syndrome in a child", Am J Phys Med Rehabil, 76, pp.200~203 (1997)
  12. Lemke DM, "Riding out the storm: sympathetic storming after traumatic brain injury", J Neurosci Nurs, 36, pp.4~9 (2004)
  13. Jarrin DC, "Short-term heart rate variability in a population-based sample of 10-year-old children", Pediatr Cardiol, 36, pp.41~48 (2015)
  14. Biswas AK, "Heart rate variability after acute traumatic brain injury in children", Crit Care Med, 28, pp.3907~3912 (2000)
  15. Baguley IJ, "Paroxysmal sympathetic hyperactivity after acquired brain injury: consensus on conceptual definition, nomenclature, and diagnostic criteria", J Neurotrauma, 31, pp.1515~1520 (2014)
  16. Fleming S, "Normal ranges of heart rate and respiratory rate in children from birth to 18 years of age: a systematic review of observational studies", Lancet, 377, pp.1011~1018 (2011)
  17. "Temperature measurement in paediatrics" (2016)[URL]
  18. "Blood pressure tables for children and adolescents: from the fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents" (2004)[URL]
  19. 심선희, "Baseline heart rate variability in children and adolescents with vasovagal syncope", Korean Journal of Pediatrics, 57(4), pp.193~198 (2014), 대한소아과학회
  20. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology, "Heart rate variability: standards of measurement, physiological interpretation, and clinical use", Eur Heart J, 17, pp.354~381 (1996)
  21. Ponnusamy A, "Comparison of heart rate variability parameters during complex partial seizures and psychogenic nonepileptic seizures", Epilepsia, 53, pp.1314~1321 (2012)
  22. Benarroch EE, "The central autonomic network: functional organization, dysfunction, and perspective", Mayo Clin Proc, 68, pp.988~1001 (1993)
  23. Lv LQ, "Prognostic influence and magnetic resonance imaging findings in paroxysmal sympathetic hyperactivity after severe traumatic brain injury", J Neurotrauma, 27, pp.1945~1950 (2010)
  24. Pignolo L, "Decreasing incidence of paroxysmal sympathetic hyperactivity syndrome in the vegetative state", J Rehabil Med, 44, pp.502~504 (2012)
  25. Baguley IJ, "Gabapentin in the management of dysautonomia following severe traumatic brain injury:a case series", J Neurol Neurosurg Psychiatry, 78, pp.539~541 (2007)
  26. Do D, "Treatment of paroxysmal sympathetic storm with labetalol", J Neurol Neurosurg Psychiatry, 69, pp.832~833 (2000)
  27. Thorley RR, "Acute hypothalamic instability in traumatic brain injury: a case report", Arch Phys Med Rehabil, 82, pp.246~249 (2001)
  28. Boeve BF, "Paroxysmal sympathetic storms (“diencephalic seizures”)after severe diffuse axonal head injury", Mayo Clin Proc, 73, pp.148~152 (1998)
  29. Baguley IJ, "The excitatory:inhibitory ratio model (EIR model): an integrative explanation of acute autonomic overactivity syndromes", Med Hypotheses, 70, pp.26~35 (2008)
  30. King ML, "Heart-rate variability in chronic traumatic brain injury", Brain Inj, 11, pp.445~453 (1997)
  31. Katz-Leurer M, "Heart rate and heart rate variability at rest and during exercise in boys who suffered a severe traumatic brain injury and typically-developed controls", Brain Inj, 24, pp.110~114 (2010)
  32. Baguley IJ, "A critical review of the pathophysiology of dysautonomia following traumatic brain injury", Neurocrit Care, 8, pp.293~300 (2008)
  33. Bonafide CP, "Development of heart and respiratory rate percentile curves for hospitalized children", Pediatrics, 131, pp.e1150~1157 (2013)

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