감각기능 회복을 보인 피질하 뇌졸중 환자의 체성감각영역 활성화 양상
Activation Pattern of the Somatosensory Cortex in Subcortical Stroke Patients with Clinical Sensory Recovery of Hand
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Abstract
Objective: To investigate the activation pattern of somatosensory cortex in subcortical stroke patients underlying recovered somatosensory capacity of hand, using functional MRI (fMRI). Method: Four patients with subcortical cerebral hemorrhage or infarction and five normal healthy volunteers were investigated. Sensory task was given on the palm of hand by brushing as a frequency of 1 Hz. In fMRI study, ten slices were obtained using the Echo Planar Imaging technique, data was statistically analyzed using SPM-99 software. Results: During the tactile stimulation of affected hand, contralateral primary somatosensory cortex was activated inall the patients. In the two patients with full recovery of tactile sense, cortical activation for paretic hand was stronger than in nonparetic hand. On the other hand, the other two patients with incomplete recovery showed that cortical activation for nonparetic hand was stronger than in paretic hand and even normal control. Conclusion: Our result suggested that functional consequences of the somatosensory cortical area were not limited to the ipsilateral hemisphere to the lesion, but affect the contralateral, nonlesioned hemisphere, in subcortical stroke patients with recovered somatosensory capacity.
참고문헌 (19)
- "재활의학 분야에서 Functional MRI의 활용", 24, pp.349~362 (2000)
- "Behavioral and neuroplastic effects of focal endothelin-1 induced sensorimotor cortex lesions", 128, pp.473~486 (2004)
- "Thalamic metabolism and corticospinal tract integrity determine motor recovery in stroke", 39, pp.460~470 (1996)
- "Electrophysiological transcortical diaschisis after cortical photothrombosis in rat brain", 27, pp.1105~1109 (1996)
- "Rapid plasticity of human cortical movement representation induced by practice", 79, pp.1117~1123 (1998)
- "Functional recuperation following lesions of the primary somatosensory fields.Study of compensatory mechanisms", 47, pp.557~563 (2001)
- "A novel passive functional MRI paradigm for preoperative identification of the somatosensory cortex", 27, pp.106~112 (2004)
- "Improvement and decline in tactile discrimination behavior after cortical plasticity induced by passive tactile coactivation", 24, pp.442~446 (2004)
- "Use-dependent growth of pyramidal neurons after neocortical damage", 14, pp.2140~2152 (1994)
- "Cortical network reorganization guided by sensory input features", 87, pp.333~343 (2002)
- "Treatment-induced cortical reorganization after stroke in humans", 31, pp.1210~1216 (2000)
- "Activation in SI and SII the influence of vibrotactile amplitude during passive and task-relevant stimulation", pp.174~184 (2004)
- "The assessment and analysis of handedness:the Edinburgh inventory", 9, pp.97~113 (1971)
- "Integrated technology for evaluation of brain function and neural plasticity", 15, pp.263~306 (2004)
- "Brain plasticity for sensory and linguistic functions a functional imaging study using magnetoencephalography with children and young adults", constanti(uje), pp.241~252 (2001)
- "Induction of bilateral plasticity in sensory cortical maps by small unilateral cortical infarcts in rats", 17, pp.623~627 (2003)
- "Neuromagnetic integrated methods tracking human brain mechanisms of sensorimotor areas ‘plastic' reorganisation", 33, pp.131~154 (2000)
- "Interhemispheric differences of sensory hand areas after monohemispheric stroke:MEG", MRI integrative study, 2001, pp.14, 474~485
- "Enlargement of cortical vibrissa representations in the surround of an ischemic cortical lesion", 162, pp.6~13 (1999)