당뇨병성 신경병증에서 신경전도검사와 이학적 변수와의 연관성
Relation of Nerve Conduction Study and Physical Parameters in Diabetic Polyneuropathy
2
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Objective: To determine the relations of parameters of nerve conduction study (NCS) and total symptom score (TSS), neuropathy impairment score (NIS) in diabetic polyneuropathy patients. Method: Seventy three patients with diabetes mellitus were included in the study. The NIS, TSS was scored in each patient by a single examiner. NCS was performed on median, ulnar, tibial, peroneal and sural nerves. Distal latencies, amplitudes and conduction velocities of compound muscles and nerves were used as parameters of NCS. The transformed individual amplitudes and nerve conduction velocities were graded in relation to the mean values and standard deviations of our control group study. Then, composite score (CS) was calculated in each individual and was correlated to the NIS, TSS using correlation analysis. Results: There was a significant linear relationship between CS and NIS-LL (neuropathy impairment score-lower limb) (r=0.718, p＜0.01) Conclusion: This study showed significant correlations between composite score and NIS-LL. Thus, composite score appears to reliably represent the objective neurologic findings. In addition, NIS-LL would be useful in determining the progression of peripheral polyneuropathy in diabetic patients.
Abstract
Objective: To determine the relations of parameters of nerve conduction study (NCS) and total symptom score (TSS), neuropathy impairment score (NIS) in diabetic polyneuropathy patients. Method: Seventy three patients with diabetes mellitus were included in the study. The NIS, TSS was scored in each patient by a single examiner. NCS was performed on median, ulnar, tibial, peroneal and sural nerves. Distal latencies, amplitudes and conduction velocities of compound muscles and nerves were used as parameters of NCS. The transformed individual amplitudes and nerve conduction velocities were graded in relation to the mean values and standard deviations of our control group study. Then, composite score (CS) was calculated in each individual and was correlated to the NIS, TSS using correlation analysis. Results: There was a significant linear relationship between CS and NIS-LL (neuropathy impairment score-lower limb) (r=0.718, p＜0.01) Conclusion: This study showed significant correlations between composite score and NIS-LL. Thus, composite score appears to reliably represent the objective neurologic findings. In addition, NIS-LL would be useful in determining the progression of peripheral polyneuropathy in diabetic patients.
참고문헌 (14)
- Llewelyn JG, "Diabetic neuropathies. in: Peripheral neuropathy, 4th ed", pp.1951~1991 (2005), Elsevier Saunders
- Pirart J, "Diabetes mellitus and its degenerative complications. A prospective study of 4,400 patients observed between 1947 and 1973", Diabetes Metab, 3, pp.97~107 (1977)
- Lamontagne A, "Electrophysiological studies in diabetic neuropathy", J Neurol Neurosurg Psychiatry, 33, pp.442~452 (1970)
- Daube JR, "Electrophysiologic testing in diabetic neuropathy. in: Diabetic neuropathy, 2nd ed", pp.222~238 (1999), Saunders
- Dyck PJ, "Detection, characterization, and staging of polyneuropathy: assessed in diabetics", Muscle Nerve, 11, pp.21~32 (1988)
- Dyck PJ, "Longitudinal assessment of diabetic polyneuropathy using a composite score in the Rochester diabetic neuropathy study cohort", Neurology, 49, pp.229~239 (1997)
- Cornblath DR, "Total neuropathy score: validation and reliability study", Neurology, 53, pp.1660~1664 (1999)
- Dyck PJ, "Use of percentiles and normal deviates to express nerve conduction and other test abnormalities", Muscle Nerve, 24, pp.307~310 (2001)
- Dyck PJ, "Individual attributes versus composite scores of nerve conduction abnormality: sensitivity, reproducibility, and concordance with impairment", Muscle Nerve, 27, pp.202~210 (2003)
- Ahn TS, "Electrophysiologic findings and clinical correlations in diabetic polyneuropathy", J Korean Rehab Med, 18, pp.99~109 (1994)
- Chang CW, "Correlation of HbA1c concentration and single-fiber EMG findings in diabetic neuropathy", Electromyogr Clin Neurophysiol, 36, pp.425~432 (1996)
- Tkac I, "Glycemic control is related to the electrophysiologic severity of diabetic peripheral sensorimotor polyneuropathy", Diabetes Care, 21, pp.1749~1752 (1998)
- Meijer JW, "Clnical diagnosis of diabetic polyneuropathy with the diabetic neuropathy symptom and diabetic neuropathy examination scores", Diabetes Care, 26, pp.697~701 (2003)
- Yarnitsky D, "Thermal testing: normative data and repeatability for various test algorithms", J Neurol Sciences, 125, pp.39~45 (1994)