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Updated risk assessments for sudden cardiac death in hypertrophic cardiomyopathy patients with implantable cardioverter-defibrillator

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초록

Hypertrophic cardiomyopathy (HCM) is a genetic disease associated with a risk of malignant ventricular tachyarrhythmias and sudden cardiac death (SCD). Assessment of the SCD risk is crucial for its clinical management, and there has been considerable interest in developing risk stratification strategies. An implantable cardioverter-defibrillator (ICD) is a life-saving treatment for patients with HCM who are at a high-risk of ventricular tachyarrhythmias and SCD. However, a substantial number of ICD recipients experience adverse effects arising from inappropriate device therapy and implant-related complications. This has led to numerous investigations of the risk of SCD and the indications for ICD implantation. American guidelines were recently updated to include new risk markers, including left ventricular systolic dysfunction, apical aneurysm, and extensive late gadolinium enhancement, while European guidelines recommend individualized estimated 5-year SCD risk assessment models. Studies evaluating other risk factors for SCD in patients with HCM have also been published. Drawing on recent guidelines and publications on clinical risk factors, we focus this review on updated risk assessments for SCD with ICD therapy in patients with HCM.

Abstract

Hypertrophic cardiomyopathy (HCM) is a genetic disease associated with a risk of malignant ventricular tachyarrhythmias and sudden cardiac death (SCD). Assessment of the SCD risk is crucial for its clinical management, and there has been considerable interest in developing risk stratification strategies. An implantable cardioverter-defibrillator (ICD) is a life-saving treatment for patients with HCM who are at a high-risk of ventricular tachyarrhythmias and SCD. However, a substantial number of ICD recipients experience adverse effects arising from inappropriate device therapy and implant-related complications. This has led to numerous investigations of the risk of SCD and the indications for ICD implantation. American guidelines were recently updated to include new risk markers, including left ventricular systolic dysfunction, apical aneurysm, and extensive late gadolinium enhancement, while European guidelines recommend individualized estimated 5-year SCD risk assessment models. Studies evaluating other risk factors for SCD in patients with HCM have also been published. Drawing on recent guidelines and publications on clinical risk factors, we focus this review on updated risk assessments for SCD with ICD therapy in patients with HCM.

참고문헌 (59)

  1. Elliott P, "Classification of the cardiomyopathies : a position statement from the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases", Eur Heart J, 29, pp.270~276 (2008)
  2. Trivedi A, "ICD therapy for primary prevention in hypertrophic cardiomyopathy", Arrhythm Electrophysiol Rev, 5, pp.188~196 (2016)
  3. Maron MS, "Enhanced American College of Cardiology", American Heart Association strategy for prevention of sudden cardiac death in high-risk patients with hypertrophic cardiomyopathy, 2019, pp.4, 644~657
  4. Maron BJ, "Efficacy of implantable cardioverter-defibrillators for the prevention of sudden death in patients with hypertrophic cardiomyopathy", N Engl J Med, 342, pp.365~373 (2000)
  5. Maron BJ, "Hypertrophic cardiomyopathy in adulthood associated with low cardiovascular mortality with contemporary management strategies", J Am Coll Cardiol, 65, pp.1915~1928 (2015)
  6. Maron BJ, "Risk stratification and outcome of patients with hypertrophic cardiomyopathy >=60years of age", Circulation, 127, pp.585~593 (2013)
  7. Maron BJ, "Management of hypertrophic cardiomyopathy : JACC state-of-the-art review", J Am Coll Cardiol, 79, pp.390~414 (2022)
  8. Schinkel AF, "Outcome and complications after implantable cardioverter defibrillator therapy in hypertrophic cardiomyopathy : systematic review and meta-analysis", Circ Heart Fail, 5, pp.552~559 (2012)
  9. Maron BJ, "Implantable cardioverter-defibrillators and prevention of sudden cardiac death in hypertrophic cardiomyopathy", JAMA, 298, pp.405~412 (2007)
  10. Vriesendorp PA, "Implantable cardioverter-defibrillators in hypertrophic cardiomyopathy : patient outcomes, rate of appropriate and inappropriate interventions, and complications", Am Heart J, 166, pp.496~502 (2013)
  11. O’Mahony C, "The long-term survival and the risks and benefits of implantable cardioverter defibrillators in patients with hypertrophic cardiomyopathy", Heart, 98, pp.116~125 (2012)
  12. Ommen SR, "2020 AHA", ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy : a report of the American College of Cardiology, J Am Coll Cardiol, pp.2020, 76[DOI]
  13. Authors, "Task Force members", 2014 ESC guidelines on diagnosis and management of hypertrophic cardiomyopathy : the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology(ESC), 2014, pp.35, 2733~2779
  14. Wang W, "Prognostic implications of nonsustained ventricular tachycardia in high-risk patients with hypertrophic cardiomyopathy", Circ Arrhythm Electrophysiol, 10, pp.e004604~ (2017)
  15. Dong Y, "Validation of the 2020 AHA", ACC risk stratification for sudden cardiac death in Chinese patients with hypertrophic cardiomyopathy, 2021, pp.8, 691653~
  16. O’Mahony C, "A novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy(HCM risk-SCD)", Eur Heart J, 35, pp.2010~2020 (2014)
  17. Spirito P, "Syncope and risk of sudden death in hypertrophic cardiomyopathy", Circulation, 119, pp.1703~1710 (2009)
  18. Priori SG, "2015ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death : the Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology(ESC). Endorsed by : Association for European Paediatric and Congenital Cardiology(AEPC)", Eur Heart J, 36, pp.2793~2867 (2015)
  19. Choi YJ, "Validation of the hypertrophic cardiomyopathy risk-sudden cardiac death calculator in Asians", Heart, 105, pp.1892~1897 (2019)
  20. Maron BJ, "Epidemiology of hypertrophic cardiomyopathy-related death : revisited in a large non-referral-based patient population", Circulation, 102, pp.858~864 (2000)
  21. Park YM, "Ventricular fibrillation and sudden cardiac arrest in apical hypertrophic cardiomyopathy : two case reports", World J Clin Cases, 9, pp.11102~11107 (2021)
  22. Xu J, "MRI T1 mapping in hypertrophic cardiomyopathy : evaluation in patients without late gadolinium enhancement and hemodynamic obstruction", Radiology, 294, pp.275~286 (2020)
  23. McLellan AJ, "Diffuse ventricular fibrosis on cardiac magnetic resonance imaging associates with ventricular tachycardia in patients with hypertrophic cardiomyopathy", J Cardiovasc Electrophysiol, 27, pp.571~580 (2016)
  24. O’Hara RP, "Personalized computational heart models with T1-mapped fibrotic remodeling predict sudden death risk in patients with hypertrophic cardiomyopathy", Elife, 11, pp.e73325~ (2022)
  25. Androulakis AF, "Entropy as a novel measure of myocardial tissue heterogeneity for prediction of ventricular arrhythmias and mortality in post-infarct patients", JACC Clin Electrophysiol, 5, pp.480~489 (2019)
  26. Ye Y, "Mean scar entropy by late gadolinium enhancement cardiac magnetic resonance is associated with ventricular arrhythmias events in hypertrophic cardiomyopathy", Front Cardiovasc Med, 8, pp.758635~ (2021)
  27. Sedaghat-Hamedani F, "Clinical outcomes associated with sarcomere mutations in hypertrophic cardiomyopathy : a meta-analysis on 7675 individuals", Clin Res Cardiol, 107, pp.30~41 (2018)
  28. Coppini R, "Clinical phenotype and outcome of hypertrophic cardiomyopathy associated with thin-filament gene mutations", J Am Coll Cardiol, 64, pp.2589~2600 (2014)
  29. Moolman JC, "Sudden death due to troponin T mutations", J Am Coll Cardiol, 29, pp.549~555 (1997)
  30. Varnava AM, "Hypertrophic cardiomyopathy : histopathological features of sudden death in cardiac troponin T disease", Circulation, 104, pp.1380~1384 (2001)
  31. Watkins H, "Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy", N Engl J Med, 332, pp.1058~1064 (1995)
  32. Shafaattalab S, "Mechanisms of arrhythmogenicity of hypertrophic cardiomyopathy-associated troponin T(TNNT2)variant I79N", Front Cell Dev Biol, 9, pp.787581~ (2021)
  33. Burns C, "Multiple gene variants in hypertrophic cardiomyopathy in the era of next-generation sequencing", Circ Cardiovasc Genet, 10, pp.e001666~ (2017)
  34. Girolami F, "Clinical features and outcome of hypertrophic cardiomyopathy associated with triple sarcomere protein gene mutations", J Am Coll Cardiol, 55, pp.1444~1453 (2010)
  35. Sadoul N, "Prospective prognostic assessment of blood pressure response during exercise in patients with hypertrophic cardiomyopathy", Circulation, 96, pp.2987~2991 (1997)
  36. Herrera-Rodriguez DL, "Genes frequently associated with sudden death in primary hypertrophic cardiomyopathy", Arch Cardiol Mex, 90, pp.58~68 (2020)
  37. Christiaans I, "The yield of risk stratification for sudden cardiac death in hypertrophic cardiomyopathy myosin-binding protein C gene mutation carriers : focus on predictive screening", Eur Heart J, 31, pp.842~848 (2010)
  38. Magri D, "Cardiopulmonary exercise test and sudden cardiac death risk in hypertrophic cardiomyopathy", Heart, 102, pp.602~609 (2016)
  39. Masri A, "Predictors of longterm outcomes in patients with hypertrophic cardiomyopathy undergoing cardiopulmonary stress testing and echocardiography", Am Heart J, 169, pp.684~692 (2015)
  40. Bayonas-Ruiz A, "Cardiopulmonary exercise test in patients with hypertrophic cardiomyopathy : a systematic review and meta-analysis", J Clin Med, 10, pp.2312~ (2021)
  41. Magri D, "Heart failure progression in hypertrophic cardiomyopathy : possible insights from cardiopulmonary exercise testing", Circ J, 80, pp.2204~2211 (2016)
  42. Lee JM, "The impact of cardiopulmonary exercise-derived scoring on prediction of cardio-cerebral outcome in hypertrophic cardiomyopathy", PLoS One, 17, pp.e0259638~ (2022)
  43. Eriksson MJ, "Long-term outcome in patients with apical hypertrophic cardiomyopathy", J Am Coll Cardiol, 39, pp.638~645 (2002)
  44. Yamaguchi H, "Hypertrophic nonobstructive cardiomyopathy with giant negative T waves(apical hypertrophy) : ventriculographic and echocardiographic features in 30 patients", Am J Cardiol, 44, pp.401~412 (1979)
  45. Kubo T, "Clinical significance of new-onset atrial fibrillation in patients with hypertrophic cardiomyopathy", ESC Heart Fail, 8, pp.5022~5030 (2021)
  46. Liao MT, "Atrial fibrillation and the risk of sudden cardiac arrest in patients with hypertrophic cardiomyopathy : a nationwide cohort study", EClinicalMedicine, 34, pp.100802~ (2021)
  47. Sugrue A, "Utility of T-wave amplitude as a non-invasive risk marker of sudden cardiac death in hypertrophic cardiomyopathy", Open Heart, 4, pp.e000561~ (2017)
  48. Biagini E, "Usefulness of electrocardiographic patterns at presentation to predict long-term risk of cardiac death in patients with hypertrophic cardiomyopathy", Am J Cardiol, 118, pp.432~439 (2016)
  49. Debonnaire P, "QRS fragmentation and QTc duration relate to malignant ventricular tachyarrhythmias and sudden cardiac death in patients with hypertrophic cardiomyopathy", J Cardiovasc Electrophysiol, 26, pp.547~555 (2015)
  50. Akboga MK, "Tp-e interval and Tp-e", QTc ratio as novel surrogate markers for prediction of ventricular arrhythmic events in hypertrophic cardiomyopathy, 2017, pp.18, 48~53
  51. Guner A, "Impaired repolarization parameters may predict fatal ventricular arrhythmias in patients with hypertrophic cardiomyopathy(from the CILICIA Registry)", J Electrocardiol, 63, pp.83~90 (2020)
  52. Song MK, "Relationship between life-threatening events and electromechanical window in patients with hypertrophic cardiomyopathy : a novel parameter for risk stratification of sudden cardiac death", Heart Rhythm, 19, pp.588~594 (2022)
  53. Serri K, "Global and regional myocardial function quantification by two-dimensional strain : application in hypertrophic cardiomyopathy", J Am Coll Cardiol, 47, pp.1175~1181 (2006)
  54. Lee HJ, "Supplementary role of left ventricular global longitudinal strain for predicting sudden cardiac death in hypertrophic cardiomyopathy", Eur Heart J Cardiovasc Imaging, 23, pp.1108~1116 (2022)
  55. Candan O, "Mechanical dispersion and global longitudinal strain by speckle tracking echocardiography : predictors of appropriate implantable cardioverter defibrillator therapy in hypertrophic cardiomyopathy", Echocardiography, 34, pp.835~842 (2017)
  56. Negri F, "Prognostic role of global longitudinal strain by feature tracking in patients with hypertrophic cardiomyopathy : the STRAIN-HCM study", Int J Cardiol, 345, pp.61~67 (2021)
  57. Geske JB, "B-type natriuretic peptide and survival in hypertrophic cardiomyopathy", J Am Coll Cardiol, 61, pp.2456~2460 (2013)
  58. Minami Y, "B-type natriuretic peptide and risk of sudden death in patients with hypertrophic cardiomyopathy", Heart Rhythm, 15, pp.1484~1490 (2018)
  59. Wu G, "N-terminal pro-brain natriuretic peptide and sudden cardiac death in hypertrophic cardiomyopathy", Heart, 107, pp.1576~1583 (2021)

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