Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IV
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Background/Aims: Acute myocardial infarction (AMI) is conventionally recognized as an urgent medical condition requiring timely and effective reperfusion therapy. However, the results of studies on the clinical outcomes in AMI according to hospital visit timings are inconclusive. To explore the difference in long-term outcomes between off- and on-hour percutaneous coronary interventions (PCI) in patients with AMI of Killip functional classification III–IV (Killip III–IV AMI). Methods: Data on the characteristics and clinical outcomes of 1,751 patients with Killip III–IV AMI between November 2011 and June 2015 from the Korea Acute Myocardial Infarction Registry-National Institutes of Health registry were analyzed. All participants were allocated into two groups: off-hour (weekdays from 6:00 PM to 8:00 AM, weekends, and legal holidays) and on-hour (weekdays from 8:00 AM to 6:00 PM) groups. The incidence of major adverse cardiac and cerebrovascular events, defined as a composite of all-cause mortality, nonfatal myocardial infarction, any revascularization, cerebrovascular accident, and stent thrombosis, was the primary endpoint. Results: Among the 1,751 patients, 572 (39.1%) underwent PCI during on-hours and 892 (60.9%) during off-hours. At the 3-year follow-up, no significant difference was found in the clinical outcomes between the two groups in both the unadjusted and propensity-score weighing-adjusted analyses. Conclusions: The outcomes of patients with Killip III–IV AMI admitted during off- and on-hours were similar.
Abstract
Background/Aims: Acute myocardial infarction (AMI) is conventionally recognized as an urgent medical condition requiring timely and effective reperfusion therapy. However, the results of studies on the clinical outcomes in AMI according to hospital visit timings are inconclusive. To explore the difference in long-term outcomes between off- and on-hour percutaneous coronary interventions (PCI) in patients with AMI of Killip functional classification III–IV (Killip III–IV AMI). Methods: Data on the characteristics and clinical outcomes of 1,751 patients with Killip III–IV AMI between November 2011 and June 2015 from the Korea Acute Myocardial Infarction Registry-National Institutes of Health registry were analyzed. All participants were allocated into two groups: off-hour (weekdays from 6:00 PM to 8:00 AM, weekends, and legal holidays) and on-hour (weekdays from 8:00 AM to 6:00 PM) groups. The incidence of major adverse cardiac and cerebrovascular events, defined as a composite of all-cause mortality, nonfatal myocardial infarction, any revascularization, cerebrovascular accident, and stent thrombosis, was the primary endpoint. Results: Among the 1,751 patients, 572 (39.1%) underwent PCI during on-hours and 892 (60.9%) during off-hours. At the 3-year follow-up, no significant difference was found in the clinical outcomes between the two groups in both the unadjusted and propensity-score weighing-adjusted analyses. Conclusions: The outcomes of patients with Killip III–IV AMI admitted during off- and on-hours were similar.
참고문헌 (34)
- Sorita A, "Off-hour presentation and outcomes in patients with acute myocardial infarction : systematic review and meta-analysis", BMJ, 348, pp.f7393~ (2014)
- Henriques JP, "Outcome of primary angioplasty for acute myocardial infarction during routine duty hours versus during off-hours", J Am Coll Cardiol, 41, pp.2138~2142 (2003)
- Ogita M, "Off-hours presentation does not affect in-hospital mortality of Japanese patients with acute myocardial infarction : J-MINUET substudy", J Cardiol, 70, pp.553~558 (2017)
- Suwa S, "Admission during offhours does not affect long-term clinical outcomes of Japanese patients with acute myocardial infarction", Int Heart J, 61, pp.215~222 (2020)
- Kim JH, "Multicenter cohort study of acute myocardial infarction in Korea : interim analysis of the Korea Acute Myocardial Infarction Registry-National Institutes of Health Registry", Circ J, 80, pp.1427~1436 (2016)
- World Medical Association, "World Medical Association Declaration of Helsinki : ethical principles for medical research involving human subjects", JAMA, 310, pp.2191~2194 (2013)
- Ibanez B, "2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation : the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology(ESC)", Eur Heart J, 39, pp.119~177 (2018)
- Neumann FJ, "2018 ESC", EACTS guidelines on myocardial revascularization, 2019, pp.40, 87~165
- Stone GW, "Prospective, multicenter study of the safety and feasibility of primary stenting in acute myocardial infarction : in-hospital and 30-day results of the PAMI stent pilot trial. Primary Angioplasty in Myocardial Infarction Stent Pilot Trial Investigators", J Am Coll Cardiol, 31, pp.23~30 (1998)
- Oh SC, "Examination of the emergency medical response system in Korea and suggestions for improvements relating to transport", IATSS Res, 28, pp.32~40 (2004)
- Fu X, "Time-to-reperfusion in patients with acute myocardial infarction and mortality in prehospital emergency care : meta-analysis", BMC Emerg Med, 20, pp.65~ (2020)
- Kragholm K, "Improvement in care and outcomes for emergency medical service-transported patients with ST-elevation myocardial infarction(STEMI)with and without prehospital cardiac arrest : a mission. Lifeline STEMI Accelerator Study", J Am Heart Assoc, 6, pp.e005717~ (2017)
- Fosbol EL, "The impact of a statewide pre-hospital STEMI strategy to bypass hospitals without percutaneous coronary intervention capability on treatment times", Circulation, 127, pp.604~612 (2013)
- Kontos MC, "Cardiac arrest and clinical characteristics, treatments and outcomes among patients hospitalized with ST-elevation myocardial infarction in contemporary practice : a report from the National Cardiovascular Data Registry", Am Heart J, 169, pp.515~522 (2015)
- Seung Hun Lee, "Pre-hospital delay and emergency medical services in acute myocardial infarction", The Korean Journal of Internal Medicine, 35(1), pp.119~132 (2020), 대한내과학회[DOI]
- Kostis WJ, "Weekend versus weekday admission and mortality from myocardial infarction", N Engl J Med, 356, pp.1099~1109 (2007)
- Berger A, "Out of hours percutaneous coronary interventions in acute coronary syndromes : long-term outcome", Heart, 92, pp.1157~1158 (2006)
- Glaser R, "Factors associated with poorer prognosis for patients undergoing primary percutaneous coronary intervention during off-hours : biology or systems failure?", JACC Cardiovasc Interv, 1, pp.681~688 (2008)
- Ryan JW, "Optimal timing of intervention in non-ST-segment elevation acute coronary syndromes : insights from the CRUSADE(Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC", AHA guidelines)Registry, 2005, pp.112, 3049~3057
- Redelmeier DA, "Weekend worriers", N Engl J Med, 356, pp.1164~1165 (2007)
- Shah AP, "Physicians.", wake up! JACC Cardiovasc Interv, 1, pp.689~691 (2008)
- Gyenes GT, "Use and timing of coronary angiography and associated in-hospital outcomes in Canadian non-ST-segment elevation myocardial infarction patients : insights from the Canadian Global Registry of Acute Coronary Events", Can J Cardiol, 29, pp.1429~1435 (2013)
- Enezate TH, "Comparison of outcomes of ST-elevation myocardial infarction treated by percutaneous coronary intervention during off-hours versus onhours", Am J Cardiol, 120, pp.1742~1754 (2017)
- Lattuca B, "On-versus off-hours presentation and mortality of ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention", JACC Cardiovasc Interv, 12, pp.2260~2268 (2019)
- Seok Oh, "Long-term outcomes in ST-elevation myocardial infarction patients treated according to hospital visit time", The Korean Journal of Internal Medicine, 37(3), pp.605~617 (2022), 대한내과학회[DOI]
- Zijlstra F, "Clinical characteristics and outcome of patients with early(<2 h), intermediate(2-4 h)and late(>4 h)presentation treated by primary coronary angioplasty or thrombolytic therapy for acute myocardial infarction", Eur Heart J, 23, pp.550~557 (2002)
- Benjamin EJ, "Heart disease and stroke statistics : 2019 update. A report from the American Heart Association", Circulation, 139, pp.e56~e528 (2019)
- Jidong Sung, "Descriptive Study on the Korean Status of Percutaneous Coronary Intervention Using National Health Insurance Service-National Sample Cohort (NHIS-NSC) Database: Focused on Temporal Trend", Korean Circulation Journal, 49(12), pp.1155~1163 (2019), 대한심장학회[DOI]
- Dong-Ho Shin, "The Current Status of Percutaneous Coronary Intervention in Korea: Based on Year 2014 & 2016 Cohort of Korean Percutaneous Coronary Intervention (K-PCI) Registry", Korean Circulation Journal, 49(12), pp.1136~1151 (2019), 대한심장학회[DOI]
- Schomig A, "A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents", N Engl J Med, 334, pp.1084~1089 (1996)
- Bhatt DL, "Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events", N Engl J Med, 354, pp.1706~1717 (2006)
- 강지훈, "The Evolving Concept of Dual Antiplatelet Therapy after Percutaneous Coronary Intervention: Focus on Unique Feature of East Asian and “Asian Paradox”", Korean Circulation Journal, 48(7), pp.537~551 (2018), 대한심장학회[DOI]
- Costa F, "Derivation and validation of the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy(PRECISE-DAPT)score : a pooled analysis of individual-patient datasets from clinical trials", Lancet, 389, pp.1025~1034 (2017)
- van den Brink FS, "Veno-arterial extracorporeal membrane oxygenation in addition to primary PCI in patients presenting with ST-elevation myocardial infarction", Neth Heart J, 26, pp.76~84 (2018)