Hepatitis B virus X Protein Promotes Liver Cancer Progression through Autophagy Induction in Response to TLR4 Stimulation

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참고문헌 (45)

1. El-Serag HB, "Hepatocellular carcinoma : epidemiology and molecular carcinogenesis", Gastroenterology, 132, pp.2557~2576 (2007)
2. Marra M, "Molecular targets and oxidative stress biomarkers in hepatocellular carcinoma : an overview", J Transl Med, 9, pp.171~ (2011)
3. Kew MC, "Hepatitis B virus x protein in the pathogenesis of hepatitis B virus-induced hepatocellular carcinoma", J Gastroenterol Hepatol, 26(Suppl 1), pp.144~152 (2011)
4. Yang S, "New insights into autophagy in hepatocellular carcinoma : mechanisms and therapeutic strategies", Am J Cancer Res, 9, pp.1329~1353 (2019)
5. Liu L, "The role of autophagy in hepatocellular carcinoma : friend or foe", Oncotarget, 8, pp.57707~57722 (2017)
6. Huang F, "Role of autophagy in tumorigenesis, metastasis, targeted therapy and drug resistance of hepatocellular carcinoma", World J Gastroenterol, 24, pp.4643~4651 (2018)
7. Cui J, "The role of autophagy in liver cancer: crosstalk in signaling pathways and potential therapeutic targets", Pharmaceuticals(Basel), 13, pp.432~ (2020)
8. He C, "Regulation mechanisms and signaling pathways of autophagy", Annu Rev Genet, 43, pp.67~93 (2009)
9. Ravikumar B, "Regulation of mammalian autophagy in physiology and pathophysiology", Physiol Rev, 90, pp.1383~1435 (2010)
10. Funderburk SF, "The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond", Trends Cell Biol, 20, pp.355~362 (2010)
11. Marquez RT, "Bcl-2:Beclin 1 complex: multiple, mechanisms regulating autophagy", apoptosis toggle switch, 2012, pp.2, 214~221
12. Jiang GM, "The relationship between autophagy and the immune system and its applications for tumor immunotherapy", Mol Cancer, 18, pp.17~ (2019)
13. Janji B, "The multifaceted role of autophagy in tumor evasion from immune surveillance", Oncotarget, 7, pp.17591~17607 (2016)
14. Yang J, "Emerging role of Toll-like receptor 4 in hepatocellular carcinoma", J Hepatocell Carcinoma, 2, pp.11~17 (2015)
15. Chung C, "Crosstalks between inflammasome and autophagy in cancer", J Hematol Oncol, 13, pp.100~ (2020)
16. Wang Z, "Autophagy : a novel therapeutic target for hepatocarcinoma(Review)", Oncol Lett, 7, pp.1345~1351 (2014)
17. Lopes JA, "Innate immunity and hepatocarcinoma : can toll-like receptors open the door to oncogenesis", World J Hepatol, 8, pp.162~182 (2016)
18. Zhan Z, "Autophagy facilitates TLR4-and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination", Autophagy, 10, pp.257~268 (2014)
19. Min Y, "Inhibition of TRAF6 ubiquitin-ligase activity by PRDX1 leads to inhibition of NFKB activation and autophagy activation", Autophagy, 14, pp.1347~1358 (2018)
20. Kim MJ, "p62 is Negatively Implicated in the TRAF6-BECN1 signaling axis for autophagy activation and cancer progression by Toll-like receptor 4(TLR4)", Cells, 9, pp.1142~ (2020)
21. Kang R, "The Beclin 1 network regulates autophagy and apoptosis", Cell Death Differ, 18, pp.571~580 (2011)
22. Morris DH, "Beclin 1-VPS34 complex architecture: understanding the nuts and bolts of therapeutic targets", Front Biol(Beijing), 10, pp.398~426 (2015)
23. Maiuri MC, "Functional and physical interaction between Bcl-X(L)and a BH3-like domain in Beclin-1", EMBO J, 26, pp.2527~2539 (2007)
24. Sir D, "The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication", Proc Natl Acad Sci U S A, 107, pp.4383~4388 (2010)
25. Tang H, "Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression", Hepatology, 49, pp.60~71 (2009)
26. Park S, "Suppression of hepatocyte nuclear factor 4 α by long-term infection of hepatitis B virus contributes to tumor cell proliferation", Int J Mol Sci, 21, pp.948~ (2020)
27. Kim MJ, "AMPKα1 regulates lung and breast cancer progression by regulating TLR4-mediated TRAF6-BECN1 signaling axis", Cancers(Basel), 12, pp.3289~ (2020)
28. 김미정, "p62 Negatively Regulates TLR4 Signaling via Functional Regulation of the TRAF6-ECSIT Complex", Immune Network, 19(3), pp.1~14 (2019), 대한면역학회
29. Kim MJ, "CRBN is a negative regulator of bactericidal activity and autophagy activation through inhibiting the ubiquitination of ECSIT and BECN1", Front Immunol, 10, pp.2203~ (2019)
30. Min Y, "Peroxiredoxin-6 negatively regulates bactericidal activity and NFκB activity by interrupting TRAF6-ECSIT complex", Front Cell Infect Microbiol, 7, pp.94~ (2017)
31. Borowicz S, "The soft agar colony formation assay", J Vis Exp, 92, pp.e51998~ (2014)
32. Franken NA, "Clonogenic assay of cells in vitro", Nat Protoc, 1, pp.2315~2319 (2006)
33. Shi CS, "TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy", Sci Signal, 3, pp.ra42~ (2010)
34. Decuypere JP, "Regulation of the autophagic bcl-2", beclin 1 interaction, 2012, pp.1, 284~312
35. Gearhart TL, "The hepatitis B virus HBx protein modulates cell cycle regulatory proteins in cultured primary human hepatocytes", Virus Res, 155, pp.363~367 (2011)
36. Wang P, "HBx induces HepG-2 cells autophagy through PI3K", Akt-mTOR pathway, 2013, pp.372, 161~168
37. Kowalik MA, "Induction of autophagy promotes the growth of early preneoplastic rat liver nodules", Oncotarget, 7, pp.5788~5799 (2016)
38. Huo X, "Identification of an autophagy-related gene signature that can improve prognosis of hepatocellular carcinoma patients", BMC Cancer, 20, pp.771~ (2020)
39. Li J, "Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial-mesenchymal transition", Carcinogenesis, 34, pp.1343~1351 (2013)
40. Liu B, "Hepatitis B virus X protein inhibits autophagic degradation by impairing lysosomal maturation", Autophagy, 10, pp.416~430 (2014)
41. Zhang Y, "HBx-associated long non-coding RNA activated by TGF-β promotes cell invasion and migration by inducing autophagy in primary liver cancer", Int J Oncol, 56, pp.337~347 (2020)
42. Luo MX, "Autophagy mediates HBx-induced nuclear factor-κB activation and release of IL-6, IL-8, and CXCL2 in hepatocytes", J Cell Physiol, 230, pp.2382~2389 (2015)
43. Fu S, "Crosstalk between hepatitis B virus X and high-mobility group box 1 facilitates autophagy in hepatocytes", Mol Oncol, 12, pp.322~338 (2018)
44. García-Aranda M, "Bcl-2 inhibition to overcome resistance to chemo-and immunotherapy", Int J Mol Sci, 19, pp.3950~ (2018)
45. Thomas S, "Targeting the Bcl-2 family for cancer therapy", Expert Opin Ther Targets, 17, pp.61~75 (2013)

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