Vitamin D-Cathelicidin Axis: at the Crossroads between Protective Immunity and Pathological Inflammation during Infection

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참고문헌 (132)

1. Watkins RR, "An update on the association of vitamin D deficiency with common infectious diseases", Can J Physiol Pharmacol, 93, pp.363~368 (2015)
2. Korf H, "Vitamin D for infections", Curr Opin Endocrinol Diabetes Obes, 21, pp.431~436 (2014)
3. 신동민, "Antimicrobial Peptides in Innate Immunity against Mycobacteria", Immune Network, 11(5), pp.245~252 (2011), 대한면역학회
4. Afacan NJ, "Therapeutic potential of host defense peptides in antibiotic-resistant infections", Curr Pharm Des, 18, pp.807~819 (2012)
5. Hasan M, "Elementary processes and mechanisms of interactions of antimicrobial peptides with membranes-single giant unilamellar vesicle studies", Adv Exp Med Biol, 1117, pp.17~32 (2019)
6. Mandal SM, "Transcriptional regulation of human defense peptides : a new direction in infection control", Biol Chem, 399, pp.1277~1284 (2018)
7. Dimitrov V, "Species-specific regulation of innate immunity by vitamin D signaling", J Steroid Biochem Mol Biol, 164, pp.246~253 (2016)
8. Liu PT, "Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response", Science, 311, pp.1770~1773 (2006)
9. Vandamme D, "A comprehensive summary of LL-37, the factotum human cathelicidin peptide", Cell Immunol, 280, pp.22~35 (2012)
10. Bikle DD, "Vitamin D metabolism, mechanism of action, and clinical applications", Chem Biol, 21, pp.319~329 (2014)
11. Yuk JM, "Vitamin D3 induces autophagy in human monocytes", macrophages via cathelicidin, 2009, pp.6, 231~243
12. Shin DM, "Mycobacterial lipoprotein activates autophagy via TLR2", 1, Cell Microbiol, pp.2010, 12[DOI]
13. Fabri M, "Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages", Sci Transl Med, 3, pp.104~ (2011)
14. Campbell GR, "Toll-like receptor 8 ligands activate a vitamin D mediated autophagic response that inhibits human immunodeficiency virus type 1", PLoS Pathog, 8, pp.e1003017~ (2012)
15. Yang R, "IL-12+IL-18 cosignaling in human macrophages and lung epithelial cells activates cathelicidin and autophagy, inhibiting intracellular mycobacterial growth", J Immunol, 200, pp.2405~2417 (2018)
16. Zittermann A, "Vitamin D and airway infections : a European perspective", Eur J Med Res, 21, pp.14~ (2016)
17. Clark A, "Role of vitamin D in the hygiene hypothesis : the interplay between vitamin D, vitamin D receptors, gut microbiota, and immune response", Front Immunol, 7, pp.627~ (2016)
18. Fan D, "Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization", Nat Med, 21, pp.808~814 (2015)
19. Nizet V, "Innate antimicrobial peptide protects the skin from invasive bacterial infection", Nature, 414, pp.454~457 (2001)
20. Svensson D, "Vitamin D-induced up-regulation of human keratinocyte cathelicidin anti-microbial peptide expression involves retinoid X receptor α", Cell Tissue Res, 366, pp.353~362 (2016)
21. Schrumpf JA, "Interleukin 13 exposure enhances vitamin D-mediated expression of the human cathelicidin antimicrobial peptide 18", LL-37 in bronchial epithelial cells, 2012, pp.80, 4485~4494
22. Gombart AF, "Human cathelicidin antimicrobial peptide(CAMP)gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1, 25-dihydroxyvitamin D3", FASEB J, 19, pp.1067~1077 (2005)
23. Wu S, "Vitamin D, vitamin D receptor, and macroautophagy in inflammation and infection", Discov Med, 11, pp.325~335 (2011)
24. Kahlenberg JM, "Little peptide, big effects : the role of LL-37 in inflammation and autoimmune disease", J Immunol, 191, pp.4895~4901 (2013)
25. Fabisiak A, "LL-37 : cathelicidin-related antimicrobial peptide with pleiotropic activity", Pharmacol Rep, 68, pp.802~808 (2016)
26. Dürr UH, "LL-37, the only human member of the cathelicidin family of antimicrobial peptides", Biochim Biophys Acta, 1758, pp.1408~1425 (2006)
27. Eissa A, "Kallikrein-related peptidase-8(KLK8)is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade", J Biol Chem, 286, pp.687~706 (2011)
28. Lee CC, "Transmembrane pores formed by human antimicrobial peptide LL-37", Biophys J, 100, pp.1688~1696 (2011)
29. Zhu Y, "Rigidification of the Escherichia coli cytoplasm by the human antimicrobial peptide LL-37 revealed by superresolution fluorescence microscopy", Proc Natl Acad Sci U S A, 116, pp.1017~1026 (2019)
30. Wang G, "Design of antimicrobial peptides : progress made with human cathelicidin LL-37", Adv Exp Med Biol, 1117, pp.215~240 (2019)
31. Martineau AR, "IFN-gamma-and TNF-independent vitamin D-inducible human suppression of mycobacteria : the role of cathelicidin LL-37", J Immunol, 178, pp.7190~7198 (2007)
32. Campbell GR, "Autophagy induction by vitamin D inhibits both Mycobacterium tuberculosis and human immunodeficiency virus type 1", Autophagy, 8, pp.1523~1525 (2012)
33. Campbell GR, "Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy", PLoS Pathog, 8, pp.e1002689~ (2012)
34. Kim EW, "Vitamin D status contributes to the antimicrobial activity of macrophages against Mycobacterium leprae", PLoS Negl Trop Dis, 12, pp.e0006608~ (2018)
35. Saleh M, "Differential modulation of hepatitis C virus replication and innate immune pathways by synthetic calcitriol-analogs", J Steroid Biochem Mol Biol, 183, pp.142~151 (2018)
36. Verway M, "Vitamin D induces interleukin-1β expression : paracrine macrophage epithelial signaling controls M. tuberculosis infection", PLoS Pathog, 9, pp.e1003407~ (2013)
37. Tang X, "P2X7 receptor regulates internalization of antimicrobial peptide LL-37 by human macrophages that promotes intracellular pathogen clearance", J Immunol, 195, pp.1191~1201 (2015)
38. Sørensen OE, "Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3", Blood, 97, pp.3951~3959 (2001)
39. Smyth D, "DrsG from Streptococcus dysgalactiae subsp. equisimilis inhibits the antimicrobial peptide LL-37", Infect Immun, 82, pp.2337~2344 (2014)
40. Li Y, "Human metapneumovirus infection inhibits cathelicidin antimicrobial peptide expression in human macrophages", Front Immunol, 9, pp.902~ (2018)
41. Woods EC, "The C. difficile clnRAB operon initiates adaptations to the host environment in response to LL-37", PLoS Pathog, 14, pp.e1007153~ (2018)
42. Talat N, "Vitamin D deficiency and tuberculosis progression", Emerg Infect Dis, 16, pp.853~855 (2010)
43. Dao CN, "Low vitamin D among HIV-infected adults : prevalence of and risk factors for low vitamin D levels in a cohort of HIV-infected adults and comparison to prevalence among adults in the US general population", Clin Infect Dis, 52, pp.396~405 (2011)
44. Bishwal SC, "Sputum proteomics reveals a shift in vitamin D-binding protein and antimicrobial protein axis in tuberculosis patients", Sci Rep, 9, pp.1036~ (2019)
45. Ashenafi S, "Vitamin D3 status and the association with human cathelicidin expression in patients with different clinical forms of active tuberculosis", Nutrients, 10, pp.721~ (2018)
46. Fujita K, "Association between Mycobacterium avium complex lung disease and serum vitamin D status, antimicrobial peptide levels, and bone mineral density", Medicine(Baltimore), 97, pp.e12463~ (2018)
47. Georgieva V, "Association between vitamin D, antimicrobial peptides and urinary tract infection in infants and young children", Acta Paediatr, 108, pp.551~556 (2019)
48. Thursfield RM, "Children with cystic fibrosis demonstrate no respiratory immunological, infective or physiological, consequences of vitamin D deficiency", J Cyst Fibros, 17, pp.657~665 (2018)
49. Yamamoto K, "Antimalarial activity of vitamin D3(VD3)does not result from VD3-induced antimicrobial agents including nitric oxide or cathelicidin", Exp Parasitol, 201, pp.67~77 (2019)
50. Yamamoto K, "Dual antiplasmodial activity of vitamin D3 and its analog, 22-oxacalcitriol, by direct and indirect mechanisms", Parasitol Int, 66, pp.89~99 (2017)
51. Goncalves-Mendes N, "Impact of vitamin D supplementation on influenza vaccine response and immune functions in deficient elderly persons : a randomized placebo-controlled trial", Front Immunol, 10, pp.65~ (2019)
52. Serré J, "Airway infection with nontypeable Haemophilus influenzae is more rapidly eradicated in vitamin D deficient mice", J Steroid Biochem Mol Biol, 187, pp.42~51 (2019)
53. Deretic V, "Autophagy balances inflammation in innate immunity", Autophagy, 14, pp.243~251 (2018)
54. Hu W, "Vitamin D3 activates the autolysosomal degradation function against Helicobacter pylori through the PDIA3 receptor in gastric epithelial cells", Autophagy, 15, pp.707~725 (2019)
55. Rekha RS, "Phenylbutyrate induces LL-37-dependent autophagy and intracellular killing of Mycobacterium tuberculosis in human macrophages", Autophagy, 11, pp.1688~1699 (2015)
56. Xu G, "Insights into battles between Mycobacterium tuberculosis and macrophages", Protein Cell, 5, pp.728~736 (2014)
57. Jo EK, "Innate immunity to mycobacteria : vitamin D and autophagy", Cell Microbiol, 12, pp.1026~1035 (2010)
58. Estrella JL, "A novel in vitro human macrophage model to study the persistence of Mycobacterium tuberculosis using vitamin D(3)and retinoic acid activated THP-1 macrophages", Front Microbiol, 2, pp.67~ (2011)
59. Huang FC, "Vitamin D differentially regulates Salmonella-induced intestine epithelial autophagy and interleukin-1β expression", World J Gastroenterol, 22, pp.10353~10363 (2016)
60. Dai J, "Vitamin D enhances resistance to Aspergillus fumigatus in mice via inhibition of excessive autophagy", Am J Transl Res, 10, pp.381~391 (2018)
61. Campbell GR, "Hormonally active vitamin D3(1alpha, 25-dihydroxycholecalciferol)triggers autophagy in human macrophages that inhibits HIV-1 infection", J Biol Chem, 286, pp.18890~18902 (2011)
62. Abdel-Mohsen MA, "Autophagy, apoptosis, vitamin D, and vitamin D receptor in hepatocellular carcinoma associated with hepatitis C virus", Medicine(Baltimore), 97, pp.e0172~ (2018)
63. Tian G, "Vitamin D3 supplementation alleviates rotavirus infection in pigs and IPEC-J2 cells via regulating the autophagy signaling pathway", J Steroid Biochem Mol Biol, 163, pp.157~163 (2016)
64. Choi Y, "Autophagy during viral infection-a double-edged sword", Nat Rev Microbiol, 16, pp.341~354 (2018)
65. Lei GS, "Mechanisms of action of vitamin D as supplemental therapy for Pneumocystis pneumonia", Antimicrob Agents Chemother, 61, pp.e01226~ (2017)
66. Hipolito VE, "Lysosome remodelling and adaptation during phagocyte activation", Cell Microbiol, 20, pp.e12824~ (2018)
67. Jo EK, "AMPK-targeted effector networks in mycobacterial infection", Front Microbiol, 10, pp.520~ (2019)
68. Alvarez JA, "Vitamin D deficiency is associated with an oxidized plasma cysteine redox potential in critically Ill children", J Steroid Biochem Mol Biol, 175, pp.164~169 (2018)
69. Alvarez JA, "Vitamin D status is independently associated with plasma glutathione and cysteine thiol", disulphide redox status in adults, 2014, pp.81, 458~466
70. Scherz-Shouval R, "Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4", EMBO J, 26, pp.1749~1760 (2007)
71. Sly LM, "1alpha, 25-dihydroxyvitamin D3-induced monocyte antimycobacterial activity is regulated by phosphatidylinositol 3-kinase and mediated by the NADPH-dependent phagocyte oxidase", J Biol Chem, 276, pp.35482~35493 (2001)
72. Yang CS, "NADPH oxidase 2 interaction with TLR2 is required for efficient innate immune responses to mycobacteria via cathelicidin expression", J Immunol, 182, pp.3696~3705 (2009)
73. Yan Y, "Autophagy as a regulator of cardiovascular redox homeostasis", Free Radic Biol Med, 109, pp.108~113 (2017)
74. Sato E, "Vitamin D-dependent cathelicidin inhibits Mycobacterium marinum infection in human monocytic cells", J Dermatol Sci, 70, pp.166~172 (2013)
75. Chun RF, "Impact of vitamin D on immune function : lessons learned from genome-wide analysis", Front Physiol, 5, pp.151~ (2014)
76. Afsal K, "Effect of 1, 25-dihydroxyvitamin D3 on the expression of mannose receptor, DC-SIGN and autophagy genes in pulmonary tuberculosis", Tuberculosis(Edinb), 99, pp.1~10 (2016)
77. Jiang P, "Autophagy and human diseases", Cell Res, 24, pp.69~79 (2014)
78. Wan M, "Prostaglandin E2 suppresses hCAP18", LL-37 expression in human macrophages via EP2, FASEB J, pp.2018, 32[DOI]
79. Gubatan J, "Vitamin D in inflammatory bowel disease : more than just a supplement", Curr Opin Gastroenterol, 34, pp.217~225 (2018)
80. Berridge MJ, "Vitamin D deficiency and diabetes", Biochem J, 474, pp.1321~1332 (2017)
81. Bennett AL, "Vitamin D metabolism and the implications for atherosclerosis", Adv Exp Med Biol, 996, pp.185~192 (2017)
82. Czaja AJ, "Evolving role of vitamin D in immune-mediated disease and its implications in autoimmune hepatitis", Dig Dis Sci, 64, pp.324~344 (2019)
83. Lu M, "Genomic effects of the vitamin D receptor : potentially the link between vitamin D, immune cells, and multiple sclerosis", Front Immunol, 9, pp.477~ (2018)
84. Takahashi T, "Cathelicidin promotes inflammation by enabling binding of self-RNA to cell surface scavenger receptors", Sci Rep, 8, pp.4032~ (2018)
85. Hurtado P, "LL-37 promotes rapid sensing of CpG oligodeoxynucleotides by B lymphocytes and plasmacytoid dendritic cells", J Immunol, 184, pp.1425~1435 (2010)
86. Zhang Z, "Mitochondrial DNA-LL-37 complex promotes atherosclerosis by escaping from autophagic recognition", Immunity, 43, pp.1137~1147 (2015)
87. Lande R, "Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus", Sci Transl Med, 3, pp.73~ (2011)
88. Yang CY, "The implication of vitamin D and autoimmunity : a comprehensive review", Clin Rev Allergy Immunol, 45, pp.217~226 (2013)
89. McHugh BJ, "Cathelicidin is a"fire alarm", generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa", PLoS Pathog, 15, pp.e1007694~ (2019)
90. Barlow PG, "The human cathelicidin LL-37 preferentially promotes apoptosis of infected airway epithelium", Am J Respir Cell Mol Biol, 43, pp.692~702 (2010)
91. Fremond CM, "IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection", J Immunol, 179, pp.1178~1189 (2007)
92. Persson LJ, "Antimicrobial peptide levels are linked to airway inflammation, bacterial colonisation and exacerbations in chronic obstructive pulmonary disease", Eur Respir J, 49, pp.1601328~ (2017)
93. Greulich T, "Altered blood levels of vitamin D, cathelicidin and parathyroid hormone in patients with sepsis-a pilot study", Anaesth Intensive Care, 45, pp.36~45 (2017)
94. Parekh D, "Vitamin D deficiency in human and murine sepsis", Crit Care Med, 45, pp.282~289 (2017)
95. 박복원, "A Study on Vitamin D and Cathelicidin Status in Patients with Rosacea: Serum Level and Tissue Expression", Annals of Dermatology, 30(2), pp.136~142 (2018), 대한피부과학회
96. Schrumpf JA, "Proinflammatory cytokines impair vitamin D-induced host defense in cultured airway epithelial cells", Am J Respir Cell Mol Biol, 56, pp.749~761 (2017)
97. Korf H, "1, 25-dihydroxyvitamin D3 curtails the inflammatory and T cell stimulatory capacity of macrophages through an IL-10-dependent mechanism", Immunobiology, 217, pp.1292~1300 (2012)
98. Zhang Y, "Vitamin D inhibits monocyte", macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1, 2012, pp.188, 2127~2135
99. Selvaraj P, "Effect of vitamin D3 on chemokine expression in pulmonary tuberculosis", Cytokine, 60, pp.212~219 (2012)
100. Harishankar M, "1, 25-Dihydroxy vitamin D3 downregulates pro-inflammatory cytokine response in pulmonary tuberculosis", Int Immunopharmacol, 23, pp.148~152 (2014)
101. Harishankar M, "Effect of vitamin D3 on chemokine levels and regulatory T-cells in pulmonary tuberculosis", Int Immunopharmacol, 34, pp.86~91 (2016)
102. Heulens N, "1, 25-dihydroxyvitamin D modulates antibacterial and inflammatory response in human cigarette smoke-exposed macrophages", PLoS One, 11, pp.e0160482~ (2016)
103. Coussens AK, "Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment", Proc Natl Acad Sci U S A, 109, pp.15449~15454 (2012)
104. Jolliffe DA, "Adjunctive vitamin D in tuberculosis treatment : meta-analysis of individual participant data", Eur Respir J, 53, pp.53~ (2019)
105. Wu S, "Vitamin D receptor pathway is required for probiotic protection in colitis", Am J Physiol Gastrointest Liver Physiol, 309, pp.G341~ (2015)
106. Marin M, "Cathelicidin modulates synthesis of toll-like receptors(TLRs)4 and 9 in colonic epithelium", Mol Immunol, 91, pp.249~258 (2017)
107. Kusaka S, "Expression of human cathelicidin peptide LL-37 in inflammatory bowel disease", Clin Exp Immunol, 191, pp.96~106 (2018)
108. Ta A, "Double-stranded RNA induces cathelicidin expression in the intestinal epithelial cells through phosphatidylinositol 3-kinase-protein kinase Cζ-Sp1 pathway and ameliorates shigellosis in mice", Cell Signal, 35, pp.140~153 (2017)
109. Yoshimura T, "The antimicrobial peptide CRAMP is essential for colon homeostasis by maintaining microbiota balance", J Immunol, 200, pp.2174~2185 (2018)
110. Rahman S, "Pulmonary tuberculosis patients with a vitamin D deficiency demonstrate low local expression of the antimicrobial peptide LL-37 but enhanced FoxP3+ regulatory T cells and IgG-secreting cells", Clin Immunol, 156, pp.85~97 (2015)
111. Steiger J, "Imatinib triggers phagolysosome acidification and antimicrobial activity against Mycobacterium bovis bacille Calmette-Guérin in glucocorticoid-treated human macrophages", J Immunol, 197, pp.222~232 (2016)
112. Tateosian NL, "IL17A augments autophagy in Mycobacterium tuberculosis-infected monocytes from patients with active tuberculosis in association with the severity of the disease", Autophagy, 13, pp.1191~1204 (2017)
113. Edfeldt K, "T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism", Proc Natl Acad Sci U S A, 107, pp.22593~22598 (2010)
114. Dang AT, "Autophagy links antimicrobial activity with antigen presentation in Langerhans cells", JCI Insight, 4, pp.126955~ (2019)
115. Klug-Micu GM, "CD40 ligand and interferon-γ induce an antimicrobial response against Mycobacterium tuberculosis in human monocytes", Immunology, 139, pp.121~128 (2013)
116. Baeke F, "Vitamin D : modulator of the immune system", Curr Opin Pharmacol, 10, pp.482~496 (2010)
117. "Vitamin D in ventilated ICU patients (R21 HL-110044)"[URL]
118. "Cholecalciferol supplementation for sepsis in the ICU (CSI)"[URL]
119. "Effect of high-dose vitamin D3 in smokers and non-smokers with and without HIV"[URL]
120. Rekha RS, "Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D3 as host directed therapy", BMC Infect Dis, 18, pp.303~ (2018)
121. Bartley J, "Vitamin D3 supplementation in adults with bronchiectasis : a pilot study", Chron Respir Dis, 15, pp.384~392 (2018)
122. Mily A, "Oral intake of phenylbutyrate with or without vitamin D3 upregulates the cathelicidin LL-37 in human macrophages : a dose finding study for treatment of tuberculosis", BMC Pulm Med, 13, pp.23~ (2013)
123. Camargo CA Jr, "Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia", Pediatrics, 130, pp.e561~ (2012)
124. Urashima M, "Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren", Am J Clin Nutr, 91, pp.1255~1260 (2010)
125. Mily A, "Significant effects of oral phenylbutyrate and vitamin D3 adjunctive therapy in pulmonary tuberculosis : a randomized controlled trial", PLoS One, 10, pp.e0138340~ (2015)
126. . A randomized, placebo-controlled, clinical trial of vitamin D supplementation in patients with pulmonary tuberculosis', "BMC Infect Dis", 2013, 22~
127. Borella E, "Vitamin D : a new anti-infective agent", Ann N Y Acad Sci, 1317, pp.76~83 (2014)
128. Anandaiah A, "Vitamin D rescues impaired Mycobacterium tuberculosis-mediated tumor necrosis factor release in macrophages of HIV-seropositive individuals through an enhanced Toll-like receptor signaling pathway in vitro", Infect Immun, 81, pp.2~10 (2013)
129. Paik S, "Autophagy : a new strategy for host-directed therapy of tuberculosis", Virulence, 10, pp.448~459 (2019)
130. Ganmaa D, "Vitamin D, tuberculin skin test conversion, and latent tuberculosis in Mongolian school-age children : a randomized, double-blind, placebo-controlled feasibility trial", Am J Clin Nutr, 96, pp.391~396 (2012)
131. Martineau AR, "High-dose vitamin D(3)during intensive-phase antimicrobial treatment of pulmonary tuberculosis : a double-blind randomised controlled trial", Lancet, 377, pp.242~250 (2011)
132. Daley P, "Adjunctive vitamin D for treatment of active tuberculosis in India : a randomised, double-blind, placebo-controlled trial", Lancet Infect Dis, 15, pp.528~534 (2015)