Cytokines in Follicular Helper T Cell Biology in Physiologic and Pathologic Conditions

키워드

참고문헌 (104)

1. Crotty S, "T follicular helper cell biology : a decade of discovery and diseases", Immunity, 50, pp.1132~1148 (2019)
2. Victora GD, "Germinal centers", Annu Rev Immunol, 40, pp.413~442 (2022)
3. Linterman MA, "IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses", J Exp Med, 207, pp.353~363 (2010)
4. Weinstein JS, "TFH cells progressively differentiate to regulate the germinal center response", Nat Immunol, 17, pp.1197~1205 (2016)
5. Ozaki K, "Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6", J Immunol, 173, pp.5361~5371 (2004)
6. Zotos D, "IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism", J Exp Med, 207, pp.365~378 (2010)
7. Quast I, "Interleukin-21, acting beyond the immunological synapse, independently controls T follicular helper and germinal center B cells", Immunity, 55, pp.1414~1430 (2022)
8. Zotos D, "The concerted change in the distribution of cell cycle phases and zone composition in germinal centers is regulated by IL-21", Nat Commun, 12, pp.7160~ (2021)
9. Vinuesa CG, "Follicular helper T cells", Annu Rev Immunol, 34, pp.335~368 (2016)
10. Kwon H, "Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors", Immunity, 31, pp.941~952 (2009)
11. Scheeren FA, "STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression", Nat Immunol, 6, pp.303~313 (2005)
12. Crotty S, "Effectors and memories : Bcl-6 and Blimp-1 in T and B lymphocyte differentiation", Nat Immunol, 11, pp.114~120 (2010)
13. Chen Z, "Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation", Sci Immunol, 8, pp.eadd1728~ (2023)
14. Moens L, "Cytokine-mediated regulation of plasma cell generation : IL-21 takes center stage", Front Immunol, 5, pp.65~ (2014)
15. Zhang Y, "Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells", J Exp Med, 215, pp.1227~1243 (2018)
16. Luo W, "IL-21R signal reprogramming cooperates with CD40 and BCR signals to select and differentiate germinal center B cells", Sci Immunol, 8, pp.eadd1823~ (2023)
17. Suto A, "Interleukin 21 prevents antigen-induced IgE production by inhibiting germ line C(ε)transcription of IL-4-stimulated B cells", Blood, 100, pp.4565~4573 (2002)
18. Yang Z, "IL-21 is a broad negative regulator of IgE class switch recombination in mouse and human B cells", J Exp Med, 217, pp.e20190472~ (2020)
19. Meli AP, "T follicular helper cell-derived IL-4 is required for IgE production during intestinal helminth infection", J Immunol, 199, pp.244~252 (2017)
20. Ise W, "T follicular helper cell-germinal center B cell interaction strength regulates entry into plasma cell or recycling germinal center cell fate", Immunity, 48, pp.702~715 (2018)
21. Kallies A, "Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1", Immunity, 26, pp.555~566 (2007)
22. Diehl SA, "STAT3-mediated up-regulation of BLIMP1 is coordinated with BCL6 down-regulation to control human plasma cell differentiation", J Immunol, 180, pp.4805~4815 (2008)
23. Klein U, "Germinal centres : role in B-cell physiology and malignancy", Nat Rev Immunol, 8, pp.22~33 (2008)
24. Nurieva RI, "Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages", Immunity, 29, pp.138~149 (2008)
25. Vogelzang A, "A fundamental role for interleukin-21 in the generation of T follicular helper cells", Immunity, 29, pp.127~137 (2008)
26. Eto D, "IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell(Tfh)differentiation", PLoS One, 6, pp.e17739~ (2011)
27. Rasheed MAU, "Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells", J Virol, 87, pp.7737~7746 (2013)
28. Fazilleau N, "The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding", Nat Immunol, 10, pp.375~384 (2009)
29. Linterman MA, "Signals that influence T follicular helper cell differentiation and function", Semin Immunopathol, 32, pp.183~196 (2010)
30. Morita R, "Human blood CXCR5(+)CD4(+)T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion", Immunity, 34, pp.108~121 (2011)
31. Dardalhon V, "IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3(-)effector T cells", Nat Immunol, 9, pp.1347~1355 (2008)
32. Hiramatsu Y, "c-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-beta inhibits c-Maf-induced IL-21 production in CD4+ T cells", J Leukoc Biol, 87, pp.703~712 (2010)
33. Bocharnikov AV, "PD-1hiCXCR5-T peripheral helper cells promote B cell responses in lupus via MAF and IL-21", JCI Insight, 4, pp.e130062~ (2019)
34. Bauquet AT, "The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells", Nat Immunol, 10, pp.167~175 (2009)
35. Ise W, "The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells", Nat Immunol, 12, pp.536~543 (2011)
36. Kroenke MA, "Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation", J Immunol, 188, pp.3734~3744 (2012)
37. Suto A, "Development and characterization of IL-21-producing CD4+ T cells", J Exp Med, 205, pp.1369~1379 (2008)
38. Schmitt N, "The cytokine TGF-β co-opts signaling via STAT3-STAT4 to promote the differentiation of human TFH cells", Nat Immunol, 15, pp.856~865 (2014)
39. Locci M, "Activin A programs the differentiation of human TFH cells", Nat Immunol, 17, pp.976~984 (2016)
40. Ma CS, "Early commitment of naïve human CD4(+)T cells to the T follicular helper(T(FH))cell lineage is induced by IL-12", Immunol Cell Biol, 87, pp.590~600 (2009)
41. Ma CS, "Functional STAT3 deficiency compromises the generation of human T follicular helper cells", Blood, 119, pp.3997~4008 (2012)
42. Schmitt N, "Blood Tfh cells come with colors", Immunity, 39, pp.629~630 (2013)
43. Choi J, "Bcl-6 is the nexus transcription factor of T follicular helper cells via repressor-of-repressor circuits", Nat Immunol, 21, pp.777~789 (2020)
44. Choi J, "Bcl6-mediated transcriptional regulation of follicular helper T cells(TFH)", Trends Immunol, 42, pp.336~349 (2021)
45. Olson WJ, "Orphan nuclear receptor NR2F6 suppresses T follicular helper cell accumulation through regulation of IL-21", Cell Reports, 28, pp.2878~2891 (2019)
46. Kim YJ, "The transcription factor Mef2d regulates B : T synapse-dependent GC-TFH differentiation and IL-21-mediated humoral immunity", Sci Immunol, 8, pp.eadf2248~ (2023)
47. Crotty S, "Follicular helper CD4 T cells(TFH)", Annu Rev Immunol, 29, pp.621~663 (2011)
48. Lee SK, "B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells", J Exp Med, 208, pp.1377~1388 (2011)
49. Miyauchi K, "Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells", Nat Commun, 12, pp.3789~ (2021)
50. Duan L, "Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation", Immunity, 54, pp.2256~2272 (2021)
51. "IL-4 downregulates BCL6 to promote memory B cell selection in germinal centers" (2023)[URL]
52. Kubo M, "The role of IL-4 derived from T follicular helper cells and TH2 cells", Int Immunol, 33, pp.717~772 (2021)
53. Yusuf I, "Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor(CD150)", J Immunol, 185, pp.190~202 (2010)
54. Kim JI, "The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines", Immunity, 10, pp.745~751 (1999)
55. Zhu J, "Differentiation of effector CD4 T cell populations(*)", Annu Rev Immunol, 28, pp.445~489 (2010)
56. Harada Y, "The 3′ enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper T cells", Immunity, 36, pp.188~200 (2012)
57. Vijayanand P, "Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V", Immunity, 36, pp.175~187 (2012)
58. Sahoo A, "Batf is important for IL-4 expression in T follicular helper cells", Nat Commun, 6, pp.7997~ (2015)
59. Li B, "Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation", EMBO J, 18, pp.420~432 (1999)
60. Rengarajan J, "Interferon regulatory factor 4(IRF4)interacts with NFATc2 to modulate interleukin 4 gene expression", J Exp Med, 195, pp.1003~1012 (2002)
61. Kuwahara M, "Bach2-Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop", Nat Commun, 7, pp.12596~ (2016)
62. Wu H, "An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells", J Immunol, 195, pp.2080~2089 (2015)
63. Naoe Y, "Repression of interleukin-4 in T helper type 1 cells by Runx", Cbf beta binding to the Il4 silencer, 2007, pp.204, 1749~1755
64. Rasheed AU, "Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi)CD4 T cells and is independent of CD57 expression", Eur J Immunol, 36, pp.1892~1903 (2006)
65. Bryant VL, "Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells : predominant role of IL-21 produced by CXCR5+ T follicular helper cells", J Immunol, 179, pp.8180~8190 (2007)
66. Xin G, "Single-cell RNA sequencing unveils an IL-10-producing helper subset that sustains humoral immunity during persistent infection", Nat Commun, 9, pp.5037~ (2018)
67. Almanan M, "IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression", Sci Adv, 6, pp.eabb0806~ (2020)
68. Wang Y, "Germinal-center development of memory B cells driven by IL-9 from follicular helper T cells", Nat Immunol, 18, pp.921~930 (2017)
69. Takatsuka S, "IL-9 receptor signaling in memory B cells regulates humoral recall responses", Nat Immunol, 19, pp.1025~1034 (2018)
70. Do-Thi VA, "Crosstalk between the producers and immune targets of IL-9", Immune Netw, 20, pp.e45~ (2020)
71. Ballesteros-Tato A, "Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation", Immunity, 36, pp.847~856 (2012)
72. DiToro D, "Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells", Science, 361, pp.eaao2933~ (2018)
73. Papillion A, "Inhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-TFH cells", Sci Immunol, 4, pp.eaaw7636~ (2019)
74. Sheikh AA, "Transcription tipping points for T follicular helper cell and T-helper 1 cell fate commitment", Cell Mol Immunol, 18, pp.528~538 (2021)
75. Wang S, "IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE", Nat Commun, 9, pp.1758~ (2018)
76. Herber D, "IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R. Fc reduces disease progression", J Immunol, 178, pp.3822~3830 (2007)
77. Odegard JM, "ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity", J Exp Med, 205, pp.2873~2886 (2008)
78. Choi JY, "Disruption of pathogenic cellular networks by IL-21 blockade leads to disease amelioration in murine lupus", J Immunol, 198, pp.2578~2588 (2017)
79. Wu H, "The IL-21-TET2-AIM2-c-MAF pathway drives the T follicular helper cell response in lupus-like disease", Clin Transl Med, 12, pp.e781~ (2022)
80. Park JS, "Interleukin-21-mediated suppression of the Pax3-Id3 pathway exacerbates the development of Sjögren’s syndrome via follicular helper T cells", Cytokine, 125, pp.154834~ (2020)
81. Zhang H, "IL-21-producing effector Tfh cells promote B cell alloimmunity in lymph nodes and kidney allografts", JCI Insight, 8, pp.e169793~ (2023)
82. Agrawal S, "Impact of IL-21-associated peripheral and brain crosstalk on the Alzheimer’s disease neuropathology", Cell Mol Life Sci, 79, pp.331~ (2022)
83. Ren HM, "IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection", Sci Immunol, 5, pp.eabb5590~ (2020)
84. Reinhardt RL, "Cytokine-secreting follicular T cells shape the antibody repertoire", Nat Immunol, 10, pp.385~393 (2009)
85. Liang HE, "Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity", Nat Immunol, 13, pp.58~66 (2011)
86. Olatunde AC, "Cytokine-skewed Tfh cells : functional consequences for B cell help", Trends Immunol, 42, pp.536~550 (2021)
87. Akiyama M, "Number of circulating follicular helper 2 T cells correlates with IgG4 and interleukin-4 levels and plasmablast numbers in IgG4-related disease", Arthritis Rheumatol, 67, pp.2476~2481 (2015)
88. Kim CJ, "The transcription factor Ets1 suppresses T follicular helper type 2 cell differentiation to halt the onset of systemic lupus erythematosus", Immunity, 49, pp.1034~1048 (2018)
89. Gowthaman U, "Identification of a T follicular helper cell subset that drives anaphylactic IgE", Science, 365, pp.eaaw6433~ (2019)
90. Pan Z, "Role of the CXCL13", CXCR5 axis in autoimmune diseases, 2022, pp.13, 850998~
91. Bombardieri M, "Ectopic lymphoid neogenesis in rheumatic autoimmune diseases", Nat Rev Rheumatol, 13, pp.141~154 (2017)
92. Bugatti S, "High expression levels of the B cell chemoattractant CXCL13 in rheumatoid synovium are a marker of severe disease", Rheumatology(Oxford), 53, pp.1886~1895 (2014)
93. Colafrancesco S, "CXCL13 as biomarker for histological involvement in Sjögren’s syndrome", Rheumatology(Oxford), 59, pp.165~170 (2020)
94. Gu-Trantien C, "CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer", JCI Insight, 2, pp.e91487~ (2017)
95. Manzo A, "Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint", Arthritis Rheum, 58, pp.3377~3387 (2008)
96. Serafini B, "Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis", Brain Pathol, 14, pp.164~174 (2004)
97. Steinmetz OM, "Analysis and classification of B-cell infiltrates in lupus and ANCA-associated nephritis", Kidney Int, 74, pp.448~457 (2008)
98. Hoellwerth M, "Revisiting the role of the CXCL13", CXCR5-associated immune axis in melanoma : potential implications for anti-PD-1-related biomarker research, 2023, pp.13, 553~
99. Li JP, "PD-1+CXCR5-CD4+ Th-CXCL13 cell subset drives B cells into tertiary lymphoid structures of nasopharyngeal carcinoma", J Immunother Cancer, 9, pp.e002101~ (2021)
100. Hao H, "IL-2 drives conversion of T follicular helper cells to T follicular regulatory cells through transcriptional regulation in systemic lupus erythematosus", Arthritis Rheumatol, 73, pp.132~142 (2020)
101. He J, "Low-dose interleukin-2 treatment selectively modulates CD4(+)T cell subsets in patients with systemic lupus erythematosus", Nat Med, 22, pp.991~993 (2016)
102. Facciotti F, "Evidence for a pathogenic role of extrafollicular, IL-10-producing CCR6+B helper T cells in systemic lupus erythematosus", Proc Natl Acad Sci U S A, 117, pp.7305~7316 (2020)
103. Crotty S, "Do memory CD4 T cells keep their cell-type programming : plasticity versus fate commitment? complexities of interpretation due to the heterogeneity of memory CD4 T cells, including T follicular helper cells", Cold Spring Harb Perspect Biol, 10, pp.a032102~ (2018)
104. Friedman MJ, "Transcriptional and epigenetic regulation of context-dependent plasticity in T-helper lineages", Immune Netw, 23, pp.e5~ (2023)

관련 논문AI추천