Effects of calcium intake, milk and dairy product intake, and blood vitamin D level on osteoporosis risk in Korean adults: analysis of the 2008 and 2009 Korea National Health and Nutrition Examination Survey
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This study was performed to determine the effects of dietary calcium (Ca) intake, milk and dairy product intake, and serum vitamin D level on bone mineral density. The survey data from the 2008-2009 Korea National Health and Nutrition Examination Survey (KNHANES) for adults (3,819 males, 5,625 females) aged > 20 years were examined; osteoporosis was defined according to the standards for Asian populations (T-score < -2.5). The risk for osteoporosis significantly decreased as Ca intake increased; this effect persisted (quartile 4 vs. quartile 1 of Ca intake: odds ratio [OR] 0.66; 95% confidence interval [CI]: 0.50-0.87) even after adjustment for gender, age, and other factors (body mass index, serum vitamin D, menstruation, female hormone intake, menopausal status, and the number of days per week of muscular strength exercise). Additionally, the risk for osteoporosis significantly decreased as the Ca/P ratio increased (quartile 4 vs. quartile 1: OR 0.76; 95% CI: 0.58-0.98). The degree of risk was 0.96 (0.66-1.38) in those who consumed < 1 portion of milk or dairy products daily, and 0.71 (0.53-0.96) in those who consumed > 1portion per day, compared with those who had zero intake. The risk for osteoporosis significantly decreased as the serum 25(OH) vitamin D level increased. From these results, we advocate an increase in Ca, milk, and dairy product intake, and that serum 25(OH) vitamin D levels be maintained within the normal range, for the maintenance of bone health and the prevention of osteoporosis in adults.
Abstract
This study was performed to determine the effects of dietary calcium (Ca) intake, milk and dairy product intake, and serum vitamin D level on bone mineral density. The survey data from the 2008-2009 Korea National Health and Nutrition Examination Survey (KNHANES) for adults (3,819 males, 5,625 females) aged > 20 years were examined; osteoporosis was defined according to the standards for Asian populations (T-score < -2.5). The risk for osteoporosis significantly decreased as Ca intake increased; this effect persisted (quartile 4 vs. quartile 1 of Ca intake: odds ratio [OR] 0.66; 95% confidence interval [CI]: 0.50-0.87) even after adjustment for gender, age, and other factors (body mass index, serum vitamin D, menstruation, female hormone intake, menopausal status, and the number of days per week of muscular strength exercise). Additionally, the risk for osteoporosis significantly decreased as the Ca/P ratio increased (quartile 4 vs. quartile 1: OR 0.76; 95% CI: 0.58-0.98). The degree of risk was 0.96 (0.66-1.38) in those who consumed < 1 portion of milk or dairy products daily, and 0.71 (0.53-0.96) in those who consumed > 1portion per day, compared with those who had zero intake. The risk for osteoporosis significantly decreased as the serum 25(OH) vitamin D level increased. From these results, we advocate an increase in Ca, milk, and dairy product intake, and that serum 25(OH) vitamin D levels be maintained within the normal range, for the maintenance of bone health and the prevention of osteoporosis in adults.
참고문헌 (33)
- Korea National Health and Nutrition Examination Survey, "Ministry of Health and Welfare", Korea Centers for Disease Control and Prevention, ~ (2010)
- Health Insurance Review & Assessment Service Report Data, , Health Insurance Review & Assessment Service, ~ (2013)
- Weinsier RL, "Dairy foods and bone health: examination of the evidence", Am J Clin Nutr, 72, pp.681~689 (2000)
- Heaney RP, "Calcium, dairy products and osteoporosis", J Am Coll Nutr, 19, pp.83S~99S (2000)
- Ruiz JC, "Influence of spontaneous calcium intake and physical exercise on the vertebral and femoral bone mineral density of children and adolescents", J Bone Miner Res, 10, pp.675~682 (1995)
- Sentipal JM, "Influence of calcium intake and growth indexes on vertebral bone mineral density in young females", Am J Clin Nutr, 54, pp.425~428 (1991)
- Feskanich D, "Calcium, vitamin D, milk consumption, and hip fractures: a prospective study among postmenopausal women", Am J Clin Nutr, 77, pp.504~511 (2003)
- Lanou AJ, "Calcium, dairy products, and bone health in children and young adults: a reevaluation of the evidence", Pediatrics, 115, pp.736~743 (2005)
- Murphy S, "Milk consumption and bone mineral density in middle aged and elderly women", BMJ, 308, pp.939~941 (1994)
- 조현주, "Relationship of nutrient intakes and bone mineral density of elderly women in Daegu, Korea", Nutrition Research and Practice, 1(4), pp.328~334 (2007), 한국영양학회
- 윤의현, "Bone Mineral Density and Food-frequency in Korean Adults: The 2008 and 2009 Korea National Health and Nutrition Examination Survey", Korean Journal of Family Medicine, 33(5), pp.287~295 (2012), 대한가정의학회
- NIH Consensus conference, "Optimal calcium intake. NIH Consensus Development Panel on Optimal Calcium Intake", JAMA, 272, pp.1942~1948 (1994)
- Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, "Food and Nutrition Board; Institute of Medicine, In Dri Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride" (1997), National Academy Press
- Abelow BJ, "Cross-cultural association between dietary animal protein and hip fracture: a hypothesis", Calcif Tissue Int, 50, pp.14~18 (1992)
- Hegsted DM, "Fractures, calcium, and the modern diet", Am J Clin Nutr, 74, pp.571~573 (2001)
- Bischoff-Ferrari HA, "Dietary calcium and serum 25-hydroxyvitamin D status in relation to BMD among U.S. adults", J Bone Miner Res, 24, pp.935~942 (2009)
- Bischoff-Ferrari HA, "Positive association between 25-hydroxy vitamin D levels and bone mineral density: a population-based study of younger and older adults", Am J Med, 116, pp.634~639 (2004)
- Lips P, "The prevalence of vitamin D inadequacy amongst women with osteoporosis: an international epidemiological investigation", J Intern Med, 260, pp.245~254 (2006)
- Melhus H, "Plasma 25-hydroxyvitamin D levels and fracture risk in a community-based cohort of elderly men in Sweden", J Clin Endocrinol Metab, 95, pp.2637~2645 (2010)
- Kanis JA, "The diagnosis of osteoporosis", J Bone Miner Res, 9, pp.1137~1141 (1994)
- Włodarek D, "Calcium intake and osteoporosis: the influence of calcium intake from dairy products on hip bone mineral density and fracture incidence - a population-based study in women over 55 years of age", Public Health Nutr, pp.1~7 (2012)
- Kardinaal AF, "Dietary calcium and bone density in adolescent girls and young women in Europe", J Bone Miner Res, 14, pp.583~592 (1999)
- Jones G, "Association between urinary potassium, urinary sodium, current diet, and bone density in prepubertal children", Am J Clin Nutr, 73, pp.839~844 (2001)
- Moro M, "Body mass is the primary determinant of midfemoral bone acquisition during adolescent growth", Bone, 19, pp.519~526 (1996)
- Uusi-Rasi K, "Determinants of bone mineralization in 8 to 20 year old Finnish females", Eur J Clin Nutr, 51, pp.54~59 (1997)
- Higashiguchi M, "Calcium intake and associated factors in a general Japanese population: baseline data of NIPPON DATA 80", 90 and the National Nutrition Survey, 2010, pp.20(Suppl 3), S549~S556
- 유춘희, "한국 남자의 연령별 골밀도에 영향을 미치는 영양요인 분석", Journal of Nutrition and Health, 37(2), pp.132~142 (2004), 한국영양학회
- 유춘희, "한국 여자의 연령별 골밀도에 영향을 미치는 영양요인 분석", Journal of Nutrition and Health, 35(7), pp.779~790 (2002), 한국영양학회
- 이정숙, "여대생의 우유와 유제품 섭취실태 및 골밀도와의 관계 연구", Journal of Nutrition and Health, 39(5), pp.451~459 (2006), 한국영양학회
- Sahni S, "Milk and yogurt consumption are linked with higher bone mineral density but not with hip fracture: the Framingham Offspring Study", Arch Osteoporos, 8, pp.119~ (2013)
- Jakobsen A, "Clinical risk factors for osteoporosis are common among elderly people in Nuuk, Greenland", Int J Circumpolar Health, 72, pp.19596~ (2013)
- Warensjö E, "Dietary calcium intake and risk of fracture and osteoporosis: prospective longitudinal cohort study", BMJ, 342, pp.d1473~ (2011)
- Kruger MC, "High-calcium, vitamin D fortified milk is effective in improving bone turnover markers and vitamin D status in healthy postmenopausal Chinese women", Eur J Clin Nutr, 66, pp.856~861 (2012)