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Association between high sensitivity C-reactive protein and dietary intake in Vietnamese young women

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BACKGROUND/OBJECTIVES: High sensitivity C-reactive protein (hsCRP) is a strong independent predictor of future cardiovasculardisease (CVD) risk. We evaluated the relationship between hsCRP and dietary intake in apparently healthy young women livingin southern Vietnam. SUBJECTS/METHODS: Serum hsCRP was measured and dietary intake data were obtained using the 1-day 24-hour recall methodin women (n = 956; mean age, 25.0 ± 5.7 years) who participated in the International Collaboration Study for the Constructionof Asian Cohort of the Korean Genome and Epidemiology Study (KoGES) in 2011. RESULTS: Women in the high risk group (> 3 mg/L) consumed fewer fruits and vegetables, total plant food, potassium, andfolate than those in the low risk group (< 1 mg/L). A multiple regression analysis after adjusting for covariates revealed asignificant negative association between hsCRP and fruit and vegetable consumption. A logistic regression analysis showedthat the odds ratio (OR) of having a high hsCRP level in women with the highest quartiles of consumption of fruits andvegetables [OR, 0.391; 95% confidence interval (CI), 0.190-0.807], potassium [OR, 0.425; 95% CI, 0.192-0.939] and folate [OR,0.490; 95% CI, 0.249-0.964] were significantly lower than those in the lowest quartiles. CONCLUSIONS: These results suggest that, in young Vietnamese women, an increased consumption of fruit and vegetablesmight be beneficial for serum hsCRP, a risk factor for future CVD events.

Abstract

BACKGROUND/OBJECTIVES: High sensitivity C-reactive protein (hsCRP) is a strong independent predictor of future cardiovasculardisease (CVD) risk. We evaluated the relationship between hsCRP and dietary intake in apparently healthy young women livingin southern Vietnam. SUBJECTS/METHODS: Serum hsCRP was measured and dietary intake data were obtained using the 1-day 24-hour recall methodin women (n = 956; mean age, 25.0 ± 5.7 years) who participated in the International Collaboration Study for the Constructionof Asian Cohort of the Korean Genome and Epidemiology Study (KoGES) in 2011. RESULTS: Women in the high risk group (> 3 mg/L) consumed fewer fruits and vegetables, total plant food, potassium, andfolate than those in the low risk group (< 1 mg/L). A multiple regression analysis after adjusting for covariates revealed asignificant negative association between hsCRP and fruit and vegetable consumption. A logistic regression analysis showedthat the odds ratio (OR) of having a high hsCRP level in women with the highest quartiles of consumption of fruits andvegetables [OR, 0.391; 95% confidence interval (CI), 0.190-0.807], potassium [OR, 0.425; 95% CI, 0.192-0.939] and folate [OR,0.490; 95% CI, 0.249-0.964] were significantly lower than those in the lowest quartiles. CONCLUSIONS: These results suggest that, in young Vietnamese women, an increased consumption of fruit and vegetablesmight be beneficial for serum hsCRP, a risk factor for future CVD events.

참고문헌 (49)

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