Long-term vegetarians have low oxidative stress, body fat, and cholesterol levels
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Excessive oxidative stress and abnormal blood lipids may cause chronic diseases. This risk can be reduced by consuming an antioxidant- and fiber-rich vegetarian diet. We compared biomarkers of oxidative stress, antioxidant capacity, and lipid profiles of sex- and age-matched long-term vegetarians and omnivores in Korea. Forty-five vegetarians (23 men and 22 women; mean age, 49.5 ± 5.3 years), who had maintained a vegetarian diet for a minimum of 15 years, and 30 omnivores (15 men and 15 women; mean age, 48.9 ± 3.6 years) participated in this study. Their 1-day,24-h recall, and 2-day dietary records were analyzed. Oxidative stress was measured by the levels of diacron reactive oxygen metabolites (d-ROM). Antioxidant status was determined by the biological antioxidant potential (BAP) and levels of endogenous antioxidant enzymes such as superoxide dismutase, catalase, and glutathione peroxidase. We observed that vegetarians had a significantly lower body fat percentage (21.6 ± 6.4%) than that of omnivores (25.4 ± 4.6%; P < 0.004). d-ROM levels were significantly lower in vegetarians than those in omnivores (331.82 ± 77.96 and 375.80± 67.26 Carratelli units; P < 0.011). Additionally, total cholesterol levels in the vegetarians and omnivores were 173.73 ± 31.42 mg/dL and 193.17± 37.89 mg/dL, respectively (P < 0.018). Low-density lipoprotein cholesterol was 101.36 ± 23.57 mg/dL and 120.60 ± 34.62 mg/dL (P < 0.005) in the vegetarians and omnivores, respectively, indicating that vegetarians had significantly lower lipid levels. Thus, oxidative stress, body fat, and cholesterol levels were lower in long-term vegetarians than those in omnivores.
Abstract
Excessive oxidative stress and abnormal blood lipids may cause chronic diseases. This risk can be reduced by consuming an antioxidant- and fiber-rich vegetarian diet. We compared biomarkers of oxidative stress, antioxidant capacity, and lipid profiles of sex- and age-matched long-term vegetarians and omnivores in Korea. Forty-five vegetarians (23 men and 22 women; mean age, 49.5 ± 5.3 years), who had maintained a vegetarian diet for a minimum of 15 years, and 30 omnivores (15 men and 15 women; mean age, 48.9 ± 3.6 years) participated in this study. Their 1-day,24-h recall, and 2-day dietary records were analyzed. Oxidative stress was measured by the levels of diacron reactive oxygen metabolites (d-ROM). Antioxidant status was determined by the biological antioxidant potential (BAP) and levels of endogenous antioxidant enzymes such as superoxide dismutase, catalase, and glutathione peroxidase. We observed that vegetarians had a significantly lower body fat percentage (21.6 ± 6.4%) than that of omnivores (25.4 ± 4.6%; P < 0.004). d-ROM levels were significantly lower in vegetarians than those in omnivores (331.82 ± 77.96 and 375.80± 67.26 Carratelli units; P < 0.011). Additionally, total cholesterol levels in the vegetarians and omnivores were 173.73 ± 31.42 mg/dL and 193.17± 37.89 mg/dL, respectively (P < 0.018). Low-density lipoprotein cholesterol was 101.36 ± 23.57 mg/dL and 120.60 ± 34.62 mg/dL (P < 0.005) in the vegetarians and omnivores, respectively, indicating that vegetarians had significantly lower lipid levels. Thus, oxidative stress, body fat, and cholesterol levels were lower in long-term vegetarians than those in omnivores.
참고문헌 (38)
- Li Y, "Oxidative stress-related genotypes, fruit and vegetable consumption and breast cancer risk", Carcinogenesis, 30, pp.777~784 (2009)
- Krajcovicová-Kudlácková M, "Effects of diet and age on oxidative damage products in healthy subjects", Physiol Res, 57, pp.647~651 (2008)
- Komatsu F, "Investigation of oxidative stress and dietary habits in Mongolian people, compared to Japanese people", Nutr Metab (Lond), 3, pp.21~ (2006)
- Valko M, "Free radicals, metals and antioxidants in oxidative stress-induced cancer", Chem Biol Interact, 160, pp.1~40 (2006)
- Rauma AL, "Antioxidant status in vegetarians versus omnivores", Nutrition, 16, pp.111~119 (2000)
- Hu Y, "Relations of glycemic index and glycemic load with plasma oxidative stress markers", Am J Clin Nutr, 84, pp.70~76 (2006)
- Roberts CK, "Effect of diet and exercise intervention on blood pressure, insulin, oxidative stress, and nitric oxide availability", Circulation, 106, pp.2530~2532 (2002)
- Sabaté J, "Publication trends of vegetarian nutrition articles in biomedical literature, 1966-1995", Am J Clin Nutr, 70, pp.601~607 (1999)
- Key TJ, "Dietary habits and mortality in 11,000 vegetarians and health conscious people: results of a 17 year follow up", BMJ, 313, pp.775~779 (1996)
- Barnard ND, "A low-fat vegan diet elicits greater macronutrient changes, but is comparable in adherence and acceptability, compared with a more conventional diabetes diet among individuals with type 2 diabetes", J Am Diet Assoc, 109, pp.263~272 (2009)
- Rizzo NS, "Vegetarian dietary patterns are associated with a lower risk of metabolic syndrome: the adventist health study 2", Diabetes Care, 34, pp.1225~1227 (2011)
- Key TJ, "Mortality in British vegetarians: review and preliminary results from EPIC-Oxford", Am J Clin Nutr, 78, pp.533~538 (2003)
- Key TJ, "Mortality in British vegetarians: results from the European Prospective Investigation into Cancer and Nutrition (EPIC-Oxford)", Am J Clin Nutr, 89, pp.1613~1619 (2009)
- Szeto YT, "Effects of a long-term vegetarian diet on biomarkers of antioxidant status and cardiovascular disease risk", Nutrition, 20, pp.863~866 (2004)
- Garcia AL, "Long-term strict raw food diet is associated with favourable plasma beta-carotene and low plasma lycopene concentrations in Germans", Br J Nutr, 99, pp.1293~1300 (2008)
- Koebnick C, "Long-term consumption of a raw food diet is associated with favorable serum LDL cholesterol and triglycerides but also with elevated plasma homocysteine and low serum HDL cholesterol in humans", J Nutr, 135, pp.2372~2378 (2005)
- Huang CJ, "Characteristics and nutrient intake of Taiwanese elderly vegetarians: evidence from a national survey", Br J Nutr, 106, pp.451~460 (2011)
- Yen CE, "Dietary intake and nutritional status of vegetarian and omnivorous preschool children and their parents in Taiwan", Nutr Res, 28, pp.430~436 (2008)
- 이유진, "The nutritional status of iron, folate, and vitamin B-12 of Buddhist vegetarians", ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION, 20(1), pp.42~49 (2011), H E C PRESS
- 이유진, "Body composition and nutrient intake of Buddhist vegetarians", ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION, 18(2), pp.265~271 (2009), H E C PRESS
- Kim MH, "Bone mineral density of Korean postmenopausal women is similar between vegetarians and nonvegetarians", Nutr Res, 27, pp.612~617 (2007)
- Lee MJ, "The unique aspects of the nutrition transition in South Korea: the retention of healthful elements in their traditional diet", Public Health Nutr, 5, pp.197~203 (2002)
- Kim DH, "Trends in the Health Status of Older Koreans", JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 58, pp.592~598 (2010), AGS
- Hirose H, "Relations between serum reactive oxygen metabolites (ROMs) and various inflammatory and metabolic parameters in a Japanese population", J Atheroscler Thromb, 16, pp.77~82 (2009)
- Cornelli U, "Bioavailability and antioxidant activity of some food supplements in men and women using the D-Roms test as a marker of oxidative stress", J Nutr, 131, pp.3208~3211 (2001)
- Komatsu F, "The association of very high hair manganese accumulation and high oxidative stress in Mongolian people", Curr Aging Sci, 2, pp.28~42 (2009)
- Komatsu F, "Relationship of dietary habits and obesity to oxidative stress in Palauan people: compared with Japanese and Mongolian people", Curr Aging Sci, 2, pp.214~222 (2009)
- Nakayama K, "Reduction of serum antioxidative capacity during hemodialysis", Clin Exp Nephrol, 11, pp.218~224 (2007)
- Lea EJ, "Public views of the benefits and barriers to the consumption of a plant-based diet", Eur J Clin Nutr, 60, pp.828~837 (2006)
- 김미현, "채식을 하는 중 ？ 노년기 여성의 영양소 섭취 상태와 식사의 질 평가", 대한지역사회영양학회지, 10(6), pp.869~879 (2005), 대한지역사회영양학회
- Kim HH, "Association of estrogen receptor-alpha gene polymorphism with pathogenesis of osteoporosis in Korean vegetarian men", Med Princ Pract, 19(3), pp.200~205 (2010), KARGER
- Miller WC, "Dietary fat, sugar, and fiber predict body fat content", J Am Diet Assoc, 94, pp.612~615 (1994)
- Spencer EA, "Diet and body mass index in 38000 EPIC-Oxford meat-eaters, fish-eaters, vegetarians and vegans", Int J Obes Relat Metab Disord, 27, pp.728~734 (2003)
- Willcox DC, "The Okinawan diet: health implications of a low-calorie, nutrient-dense, antioxidantrich dietary pattern low in glycemic load", J Am Coll Nutr, 28(Suppl), pp.500~516 (2009)
- Wilson AK, "Nutrient intake and iron status of Australian male vegetarians", Eur J Clin Nutr, 53, pp.189~194 (1999)
- Crujeiras AB, "A role for fruit content in energy-restricted diets in improving antioxidant status in obese women during weight loss", Nutrition, 22, pp.593~599 (2006)
- Vassalle C, "Determinants of oxidative stress related to gender: relevance of age and smoking habit", Clin Chem Lab Med, 49, pp.1509~1513 (2011)
- Haldar S, "Influence of habitual diet on antioxidant status: a study in a population of vegetarians and omnivores", Eur J Clin Nutr, 61, pp.1011~1022 (2007)