Multiple Cardiovascular Manifestations in a Patient with Autosomal Dominant Polycystic Kidney Disease
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초록
Autosomal dominant polycystic kidney disease (ADPKD) is a systemic disorder associated with various extrarenal complications. The major cardiovascular complications of ADPKD include valvulopathies and vascular ectasia. A 64-year-old man who was diagnosedwith ADPKD seven years previously was admitted to our hospital for heart failure. Pelvic computed tomography revealedmultiple variable-sized cysts in both kidneys. Transthoracic echocardiography showed enlargement of the left ventricle andleft atrium. Severe mitral regurgitation and moderate aortic regurgitation with annuloaortic ectasia were observed. The left maincoronary artery was dilated. The patient had various cardiovascular features associated with ADPKD.
Abstract
Autosomal dominant polycystic kidney disease (ADPKD) is a systemic disorder associated with various extrarenal complications. The major cardiovascular complications of ADPKD include valvulopathies and vascular ectasia. A 64-year-old man who was diagnosedwith ADPKD seven years previously was admitted to our hospital for heart failure. Pelvic computed tomography revealedmultiple variable-sized cysts in both kidneys. Transthoracic echocardiography showed enlargement of the left ventricle andleft atrium. Severe mitral regurgitation and moderate aortic regurgitation with annuloaortic ectasia were observed. The left maincoronary artery was dilated. The patient had various cardiovascular features associated with ADPKD.
참고문헌 (12)
- Gabow PA, "Autosomal dominant polycystic kidney disease", N Engl J Med, 329, pp.332~342 (1993)
- Perrone RD, "Extrarenal manifestations of ADPKD", Kidney Int, 51, pp.2022~2036 (1997)
- Hossack KF, "Echocardiographic findings in autosomal dominant polycystic kidney disease", N Engl J Med, 319, pp.907~912 (1988)
- Leier CV, "Cardiovascular abnormalities associated with adult polycystic kidney disease", Ann Intern Med, 100, pp.683~688 (1984)
- Hadimeri H, "Coronary aneurysms in patients with autosomal dominant polycystic kidney disease", J Am Soc Nephrol, 9, pp.837~841 (1998)
- Basile C, "Spontaneous coronary artery dissection: one more extrarenal manifestation of autosomal dominant polycystic kidney disease?", J Nephrol, 22, pp.414~416 (2009)
- Helal I, "Prevalence of cardiovascular events in patients with autosomal dominant polycystic kidney disease", Am J Nephrol, 36, pp.362~370 (2012)
- Lumiaho A, "Mitral valve prolapse and mitral regurgitation are common in patients with polycystic kidney disease type 1", Am J Kidney Dis, 38, pp.1208~1216 (2001)
- Torres VE, "Autosomal dominant polycystic kidney disease : the last 3 years", Kidney Int, 76, pp.149~168 (2009)
- 김정근, "A Case of Severe Aortic Valve Regurgitation Caused by an Ascending Aortic Aneurysm in a Young Patient With Autosomal Dominant Polycystic Kidney Disease and Normal Renal Function", Korean Circulation Journal, 42(2), pp.136~139 (2012), 대한심장학회
- Paavola J, "Polycystin-2 mutations lead to impaired calcium cycling in the heart and predispose to dilated cardiomyopathy", J Mol Cell Cardiol, 58, pp.199~208 (2013)
- 최성준, "다낭성 신질환에 동반된 확장성 심근증 1예", Journal of Cardiovascular Ultrasound, 9(2), pp.152~156 (2001), 한국심초음파학회