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Exercise-Induced Intrapulmonary Arteriovenous Shunt in a Patient Complaining of Dyspnea during Strenuous Exercise

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초록

A 51-year-old highly fit man presented for dyspnea with strenuous aerobic exercise. The patient was asymptomatic and all tests werenormal at rest. With increasing exercise intensity, he suddenly complained of dyspnea and showed a severe exercise-inducedhypoxemia with an excessive alveolar-arterial oxygen tension difference. In agitated saline contrast echocardiography at peak exercise,a large amount of left to right shunt was identified after > 5 cardiac cycles, which suggests the presence of exercise-inducedintrapulmonary arteriovenous shunt in this patient.

Abstract

A 51-year-old highly fit man presented for dyspnea with strenuous aerobic exercise. The patient was asymptomatic and all tests werenormal at rest. With increasing exercise intensity, he suddenly complained of dyspnea and showed a severe exercise-inducedhypoxemia with an excessive alveolar-arterial oxygen tension difference. In agitated saline contrast echocardiography at peak exercise,a large amount of left to right shunt was identified after > 5 cardiac cycles, which suggests the presence of exercise-inducedintrapulmonary arteriovenous shunt in this patient.

참고문헌 (7)

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  4. Vogiatzis I, "The contribution of intrapulmonary shunts to the alveolar-to-arterial oxygen difference during exercise is very small", J Physiol, 586, pp.2381~2391 (2008)
  5. Lovering AT, "Direct demonstration of 25- and 50-microm arteriovenous pathways in healthy human and baboon lungs", Am J Physiol Heart Circ Physiol, 292, pp.H1777~H1781 (2007)
  6. Stickland MK, "Exercise-induced intrapulmonary arteriovenous shunting and pulmonary gas exchange", Exerc Sport Sci Rev, 34, pp.99~106 (2006)
  7. Laurie SS, "Hypoxia-induced intrapulmonary arteriovenous shunting at rest in healthy humans", J Appl Physiol, 109, pp.1072~1079 (2010)

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