Three-Dimensional Myocardial Strain for the Prediction of Clinical Events in Patients With ST-Segment Elevation Myocardial Infarction
1
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
BACKGROUND: Two-dimensional (2D) strain provides more predictive power than ejection fraction (EF) in patients with ST-elevation myocardial infarction (STEMI). 3D strain and EF are also expected to have better clinical usefulness and overcome several inherent limitations of 2D strain. We aimed to clarify the prognostic significance of 3D strain analysis in patients with STEMI. METHODS: Patients who underwent successful revascularization for STEMI were retrospectively recruited. In addition to conventional parameters, 3D EF, global longitudinal strain (GLS), global area strain (GAS), as well as 2D GLS were obtained. We constructed a composite outcome consisting of all-cause death or re-hospitalization for acute heart failure or ventricular arrhythmia. RESULTS: Of 632 STEMI patients, 545 patients (86.2%) had a reliable 3D strain analysis. During median follow-up of 49.5 months, 55 (10.1%) patients experienced the adverse outcome. Left ventricle EF, 2D GLS, 3D EF, 3D GLS, and 3D GAS were significantly associated with poor outcomes. (all, p < 0.001) The maximum likelihood-ratio test was performed to evaluate the additional prognostic value of 2D GLS or 3D GLS over the prognostic model consisting of clinical characteristics and EF, and the likelihood ratio was 15.9 for 2D GLS (p < 0.001) and 1.49 for 3D GLS (p = 0.22). CONCLUSIONS: The predictive power of 3D strain was slightly lower than the 2D strain. Although we can obtain 3D strains, volume, and EF simultaneously in same cycle, the clinical implications of 3D strains in STEMI need to be investigated further.
Abstract
BACKGROUND: Two-dimensional (2D) strain provides more predictive power than ejection fraction (EF) in patients with ST-elevation myocardial infarction (STEMI). 3D strain and EF are also expected to have better clinical usefulness and overcome several inherent limitations of 2D strain. We aimed to clarify the prognostic significance of 3D strain analysis in patients with STEMI. METHODS: Patients who underwent successful revascularization for STEMI were retrospectively recruited. In addition to conventional parameters, 3D EF, global longitudinal strain (GLS), global area strain (GAS), as well as 2D GLS were obtained. We constructed a composite outcome consisting of all-cause death or re-hospitalization for acute heart failure or ventricular arrhythmia. RESULTS: Of 632 STEMI patients, 545 patients (86.2%) had a reliable 3D strain analysis. During median follow-up of 49.5 months, 55 (10.1%) patients experienced the adverse outcome. Left ventricle EF, 2D GLS, 3D EF, 3D GLS, and 3D GAS were significantly associated with poor outcomes. (all, p < 0.001) The maximum likelihood-ratio test was performed to evaluate the additional prognostic value of 2D GLS or 3D GLS over the prognostic model consisting of clinical characteristics and EF, and the likelihood ratio was 15.9 for 2D GLS (p < 0.001) and 1.49 for 3D GLS (p = 0.22). CONCLUSIONS: The predictive power of 3D strain was slightly lower than the 2D strain. Although we can obtain 3D strains, volume, and EF simultaneously in same cycle, the clinical implications of 3D strains in STEMI need to be investigated further.
참고문헌 (28)
- Gorcsan J 3rd, "Echocardiographic assessment of myocardial strain", J Am Coll Cardiol, 58, pp.1401~1413 (2011)
- Mollema SA, "Viability assessment with global left ventricular longitudinal strain predicts recovery of left ventricular function after acute myocardial infarction", Circ Cardiovasc Imaging, 3, pp.15~23 (2010)
- Antoni ML, "Time course of global left ventricular strain after acute myocardial infarction", Eur Heart J, 31, pp.2006~2013 (2010)
- Hung CL, "Longitudinal and circumferential strain rate, left ventricular remodeling, and prognosis after myocardial infarction", J Am Coll Cardiol, 56, pp.1812~1822 (2010)
- Ersbøll M, "Prediction of all-cause mortality and heart failure admissions from global left ventricular longitudinal strain in patients with acute myocardial infarction and preserved left ventricular ejection fraction", J Am Coll Cardiol, 61, pp.2365~2373 (2013)
- Cha MJ, "Prognostic power of global 2D strain according to left ventricular ejection fraction in patients with ST elevation myocardial infarction", PLoS One, 12, pp.e0174160~ (2017)
- Antoni ML, "Prognostic importance of strain and strain rate after acute myocardial infarction", Eur Heart J, 31, pp.1640~1647 (2010)
- Wang N, "Regional cardiac dysfunction and outcome in patients with left ventricular dysfunction, heart failure, or both after myocardial infarction", Eur Heart J, 37, pp.466~472 (2016)
- Kalam K, "Prognostic implications of global LV dysfunction : a systematic review and meta-analysis of global longitudinal strain and ejection fraction", Heart, 100, pp.1673~1680 (2014)
- Yoshihiro Seo, "Current Status of 3-Dimensional Speckle Tracking Echocardiography: A Review from Our Experiences", Journal of Cardiovascular Imaging, 22(2), pp.49~57 (2014), 한국심초음파학회
- Badano LP, "Use of three-dimensional speckle tracking to assess left ventricular myocardial mechanics : inter-vendor consistency and reproducibility of strain measurements", Eur Heart J Cardiovasc Imaging, 14, pp.285~293 (2013)
- Negishi K, "Role of temporal resolution in selection of the appropriate strain technique for evaluation of subclinical myocardial dysfunction", Echocardiography, 29, pp.334~339 (2012)
- O’Gara PT, "2013 ACCF", AHA guideline for the management of ST-elevation myocardial infarction : a report of the American College of Cardiology Foundation, J Am Coll Cardiol, pp.2013, 61[DOI]
- Lang RM, "EAE", ASE recommendations for image acquisition and display using three-dimensional echocardiography, 2012, pp.13, 1~46
- Hicks KA, "2014 ACC", AHA key data elements and definitions for cardiovascular endpoint events in clinical trials : a report of the American College of Cardiology, Circulation, pp.2015, 132[DOI]
- Abate E, "Value of three-dimensional speckle-tracking longitudinal strain for predicting improvement of left ventricular function after acute myocardial infarction", Am J Cardiol, 110, pp.961~967 (2012)
- Shin SH, "Impact of area strain by 3D speckle tracking on clinical outcome in patients after acute myocardial infarction", Echocardiography, 33, pp.1854~1859 (2016)
- Jasaityte R, "Comparison of a new methodology for the assessment of 3D myocardial strain from volumetric ultrasound with 2D speckle tracking", Int J Cardiovasc Imaging, 28, pp.1049~1060 (2012)
- Reant P, "Evaluation of global left ventricular systolic function using three-dimensional echocardiography speckle-tracking strain parameters", J Am Soc Echocardiogr, 25, pp.68~79 (2012)
- Hayat D, "Comparison of real-time three-dimensional speckle tracking to magnetic resonance imaging in patients with coronary heart disease", Am J Cardiol, 109, pp.180~186 (2012)
- Saito K, "Comprehensive evaluation of left ventricular strain using speckle tracking echocardiography in normal adults : comparison of three-dimensional and two-dimensional approaches", J Am Soc Echocardiogr, 22, pp.1025~1030 (2009)
- Luis SA, "Use of three-dimensional speckle-tracking echocardiography for quantitative assessment of global left ventricular function : a comparative study to three-dimensional echocardiography", J Am Soc Echocardiogr, 27, pp.285~291 (2014)
- Muraru D, "Left ventricular myocardial strain by three-dimensional speckle-tracking echocardiography in healthy subjects : reference values and analysis of their physiologic and technical determinants", J Am Soc Echocardiogr, 27, pp.858~871 (2014)
- Gayat E, "Reproducibility and inter-vendor variability of left ventricular deformation measurements by three-dimensional speckle-tracking echocardiography", J Am Soc Echocardiogr, 24, pp.878~885 (2011)
- Jasaityte R, "Current state of three-dimensional myocardial strain estimation using echocardiography", J Am Soc Echocardiogr, 26, pp.15~28 (2013)
- Prastaro M, "Expert review on the prognostic role of echocardiography after acute myocardial infarction", J Am Soc Echocardiogr, 30, pp.431~443 (2017)
- Huttin O, "Global and regional myocardial deformation mechanics of microvascular obstruction in acute myocardial infarction : a three dimensional speckle-tracking imaging study", Int J Cardiovasc Imaging, 31, pp.1337~1346 (2015)
- Munk K, "Global left ventricular longitudinal systolic strain for early risk assessment in patients with acute myocardial infarction treated with primary percutaneous intervention", J Am Soc Echocardiogr, 25, pp.644~651 (2012)