Global longitudinal strain manually measured from mid‑myocardial lengths is a reliable alternative to speckle tracking global longitudinal strain
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Background Global longitudinal strain (GLS) is a useful marker for the echocardiographic evaluation of left ventricular (LV) systolic dysfunction. Presently GLS is derived from speckle tracking of LV images, but speckle tracking software is not always available. We seek to determine if manually measured GLS (MM-GLS) by assessing mid-myocardial lengths can be a reliable alternative to speckle tracking GLS (ST-GLS). Methods Transthoracic echocardiogram images of a tertiary hospital in Australia were retrospectively analyzed to study the relationships between ST-GLS, MM-GLS, and LV ejection fraction (LVEF). We further evaluated the impact of image quality and regional wall motion abnormalities on those relationships. Results Echocardiography studies from 154 patients were included (female sex, 36%; mean age, 61.7 ± 14.8 years). The average LVEF was 51.3% ± 11.3% and the average ST-GLS was 16.7 ± 3.8. MM-GLS strongly correlated with ST-GLS (intraclass correlation coefficient, 0.986; P < 0.001) and with LVEF regardless of the presence of regional wall motion abnormalities. If using GLS cutoff of more than 18% as normal, 97.5% of studies with normal ST-GLS had normal MM-GLS. If using GLS cutoff as less than 16% as abnormal, 95.5% of studies with abnormal ST-GLS had abnormal MM-GLS. There was no case with ST-GLS > 18% and MM-GLS < 16%, nor were there any case in with ST-GLS < 16% and MM-GLS > 18%. Conclusions MM-GLS correlates strongly with ST-GLS. If ST-GLS cannot be accurately assessed, MM-GLS may be a useful alternative to provide GLS values in both clinical and research studies.
Abstract
Background Global longitudinal strain (GLS) is a useful marker for the echocardiographic evaluation of left ventricular (LV) systolic dysfunction. Presently GLS is derived from speckle tracking of LV images, but speckle tracking software is not always available. We seek to determine if manually measured GLS (MM-GLS) by assessing mid-myocardial lengths can be a reliable alternative to speckle tracking GLS (ST-GLS). Methods Transthoracic echocardiogram images of a tertiary hospital in Australia were retrospectively analyzed to study the relationships between ST-GLS, MM-GLS, and LV ejection fraction (LVEF). We further evaluated the impact of image quality and regional wall motion abnormalities on those relationships. Results Echocardiography studies from 154 patients were included (female sex, 36%; mean age, 61.7 ± 14.8 years). The average LVEF was 51.3% ± 11.3% and the average ST-GLS was 16.7 ± 3.8. MM-GLS strongly correlated with ST-GLS (intraclass correlation coefficient, 0.986; P < 0.001) and with LVEF regardless of the presence of regional wall motion abnormalities. If using GLS cutoff of more than 18% as normal, 97.5% of studies with normal ST-GLS had normal MM-GLS. If using GLS cutoff as less than 16% as abnormal, 95.5% of studies with abnormal ST-GLS had abnormal MM-GLS. There was no case with ST-GLS > 18% and MM-GLS < 16%, nor were there any case in with ST-GLS < 16% and MM-GLS > 18%. Conclusions MM-GLS correlates strongly with ST-GLS. If ST-GLS cannot be accurately assessed, MM-GLS may be a useful alternative to provide GLS values in both clinical and research studies.
참고문헌 (18)
- Klaeboe LG, "Echocardiographic assessment of left ventricular systolic function", J Echocardiogr, 17, pp.10~16 (2019)
- Haji K, "Improving the characterization of stage A and B heart failure by adding global longitudinal strain", JACC Cardiovasc Imaging, 15, pp.1380~1387 (2022)
- Leitman M, "Two-dimensional strain-a novel software for real-time quantitative echocardiographic assessment of myocardial function", J Am Soc Echocardiogr, 17, pp.1021~1029 (2004)
- Collier P, "A test in context : myocardial strain measured by speckle-tracking echocardiography", J Am Coll Cardiol, 69, pp.1043~1056 (2017)
- Nagata Y, "Intervendor variability of two-dimensional strain using vendor-specific and vendor-independent software", J Am Soc Echocardiogr, 28, pp.630~641 (2015)
- Kobayashi Y, "Comparison of left ventricular manual versus automated derived longitudinal strain : implications for clinical practice and research", Int J Cardiovasc Imaging, 32, pp.429~437 (2016)
- Okada K, "Left ventricular global longitudinal strain calculated from manually traced endocardial border lengths utilizing the images for routine ejection fraction measurement by biplane method of disks", J Med Ultrason, 2020(47), pp.91~96 (2001)
- Yang H, "Research to practice : assessment of left ventricular global longitudinal strain for surveillance of cancer chemotherapeutic-related cardiac dysfunction", JACC Cardiovasc Imaging, 11, pp.1196~1201 (2018)
- Stanton T, "Prediction of all-cause mortality from global longitudinal speckle strain : comparison with ejection fraction and wall motion scoring", Circ Cardiovasc Imaging, 2, pp.356~364 (2009)
- Fallah-Rad N, "The utility of cardiac biomarkers, tissue velocity and strain imaging, and cardiac magnetic resonance imaging in predicting early left ventricular dysfunction in patients with human epidermal growth factor receptor II-positive breast cancer treated with adjuvant trastuzumab therapy", J Am Coll Cardiol, 57, pp.2263~2270 (2011)
- Poterucha JT, "Changes in left ventricular longitudinal strain with anthracycline chemotherapy in adolescents precede subsequent decreased left ventricular ejection fraction", J Am Soc Echocardiogr, 25, pp.733~740 (2012)
- Phelan D, "Relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography is both sensitive and specific for the diagnosis of cardiac amyloidosis", Heart, 98, pp.1442~1448 (2012)
- Mohty D, "Cardiac amyloidosis : updates in diagnosis and management", Arch Cardiovasc Dis, 106, pp.528~540 (2013)
- Kurt M, "Impact of contrast echocardiography on evaluation of ventricular function and clinical management in a large prospective cohort", J Am Coll Cardiol, 53, pp.802~810 (2009)
- Nagata Y, "Impact of image quality on reliability of the measurements of left ventricular systolic function and global longitudinal strain in 2D echocardiography", Echo Res Pract, 5, pp.27~39 (2018)
- Zhao L, "Epicardial adipose tissue is associated with left atrial dysfunction in people without obstructive coronary artery disease or atrial fibrillation", Can J Cardiol, 34, pp.1019~1025 (2018)
- Lee JH, "Strain analysis of the right ventricle using two-dimensional echocardiography", J Cardiovasc Imaging, 26, pp.111~124 (2018)
- Voigt JU, "How to do LA strain", Eur Heart J Cardiovasc Imaging, 21, pp.715~717 (2020)