냉자극에 대한 맥율 변화 예비 연구
A Feasibility Study of Pulse Rate Per Respiration as an Indicator for the Reaction to Cold Stress
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초록
Cold and Heat pattern identification(CHPI) in traditional East Asian medicine(TEAM) is one of the major indicator to distinguish characteristics of disease and to determine treatment method. Basic parameters to determine CHPI include the pulse rate, respiration rate, and pulse power. Studies to associate physiological responses of human body by cold stress(CS) with CHPI in TEAM were rarely done so far. This study aims to explore the effects of cold stress on pulse signal via a feasibility study for three subjects and investigate some indices which can reflect autonomic nerve reaction(ANR). We measured radial pulse signals and respiration signal of the investigated subjects before the CS, during the CS which continues for 5 minutes, and immediately after the CS, respectively. Finally, we analyzed the pulse rate (P), respiration rate (R), pulse power, pulse depth, and pulse rate per respiration (P/R ratio). As a result, the P/R ratio showed a consistently decreasing tendency through the CS stimulation process, while other parameters behaved more complex and in subject-specific ways. It implies that, among candidate parameters, the P/R ratio is a simple but the most probable parameter that can be used as the ANR indicator. This result is also consistent with the theory in TEAM scripts, in which the P/R ratio is predicted to be a direct indicator for the CHPI. This pilot study shows that P/R ratio can be more appropriately associated with the ANR than heart rate or respiration rate alone. Extensive studies will be necessary to verify or confirm the P/R ratio as an appropriate and well defined parameter for ANR.
Abstract
Cold and Heat pattern identification(CHPI) in traditional East Asian medicine(TEAM) is one of the major indicator to distinguish characteristics of disease and to determine treatment method. Basic parameters to determine CHPI include the pulse rate, respiration rate, and pulse power. Studies to associate physiological responses of human body by cold stress(CS) with CHPI in TEAM were rarely done so far. This study aims to explore the effects of cold stress on pulse signal via a feasibility study for three subjects and investigate some indices which can reflect autonomic nerve reaction(ANR). We measured radial pulse signals and respiration signal of the investigated subjects before the CS, during the CS which continues for 5 minutes, and immediately after the CS, respectively. Finally, we analyzed the pulse rate (P), respiration rate (R), pulse power, pulse depth, and pulse rate per respiration (P/R ratio). As a result, the P/R ratio showed a consistently decreasing tendency through the CS stimulation process, while other parameters behaved more complex and in subject-specific ways. It implies that, among candidate parameters, the P/R ratio is a simple but the most probable parameter that can be used as the ANR indicator. This result is also consistent with the theory in TEAM scripts, in which the P/R ratio is predicted to be a direct indicator for the CHPI. This pilot study shows that P/R ratio can be more appropriately associated with the ANR than heart rate or respiration rate alone. Extensive studies will be necessary to verify or confirm the P/R ratio as an appropriate and well defined parameter for ANR.
참고문헌 (30)
- Park, Y. B., "Detection and interpretation of wan-maeck by the pulse diagnostic apparatus – on the pulse", resperatio rate -, 1997, pp.18(1), 143~156
- Kang, D.W., "Diagnostic method in Korean medicine :Pulse diagnosis", Animal Clinical Medicine, 8(2), pp.58~64 (2010)
- Park, Y.B., "A Study on Pulse Rate Detection System", Journal of the Institute of Electronics Engineers of Korea, 20(1), pp.437~440 (1997)
- Lee, H. J., "A Study of Correlation between Pulse-Respiration Ratio and Characteristics of Thermal Temperature", The Journal Of The Korea Institute Of Oriental Medicinal Diagnostics, 12(1), pp.103~130 (2008)
- Bae, N.S., "Correlation analysis for 9 respiratory indices and the Cold and Heat score", The Journal Of The Korea Institute Of Oriental Medical Diagnostics, 12(2), pp.96~106 (2009)
- Kreh, A., "Vascular reactions correlated with pain due to cold", Exp. Neurol, 85, pp.533~546 (1984)
- Kellogg, D.L., "In vivo mechanisms of cutaneous vasodilation and vasoconstriction in humans during thermoregulatory challenges", Journal of Applied Physiology, 100(5), pp.709~1718 (2006)
- Bader, M.E., "Effect of local cooling on finger blood flow in individuals exposed to warm ambient temperature", Journal of Applied Physiology, 3, pp.508~512 (1950)
- Safar, M.E., "Disturbance of macro- and microcirculation: relations with pulse pressure and cardiac organ damage", American Journal of Physiology, 293(1), pp.H1~H7 (2007)
- Jiang, X.-H., "Sympathetic nervous system mediates cold stress-induced suppression of natural killer cytotoxicity in rats", Neuroscience Letters, 357(1), pp.1~4 (2004)
- Harada, N., "Cold-stress tests involving finger skin temperature measurement for evaluation of vascular disorders in hand-arm vibration syndrome: review of the literature", Int Arch Occup Environ Health, 75, pp.14~19 (2002)
- Selkurt, E.E.., "Basic Physiology for the Health Sciences", pp.554~557 (1975), Littel, Brown and Co.
- Park, W. G., "Differences of Cardiovascular Responses to Hand Cooling between Male and Female", The Keimyung Univ. Med. J, 3(2), pp.175~186 (1984)
- Parashos, G., "Effect of Cold, Isometric Exercise, and Combination of Both on Aoric Pulse in Healthy Subjects", The American Journal of Cardiology, 93, pp.265~267 (2004)
- Huang, C.M., "Evidence-Baced Complementary and Alternative Medicine: Article ID 751317", ~ (2011)
- Jatoi, N.A., "The acute effects of mental arithmetic, cold pressor and maximal voluntary contraction on arterial stiffness in young healthy subjects", Artery Research, 8, pp.44~50 (2014)
- Fisher, A.N., "Temperature and Press Threshold Measurements in Trigger Points", Thermology, 1(4), pp.212~215 (1986)
- Park, Y.J., "A Study on Correlation between Bian Zheng with Autonomic Functions –Based on Skin Resistance Variability, Han Zheng, Re Zheng and Xu Zheng-.", The Journal Of The Korea Institute Of Oriental Medical Diagnostics, 6(1), pp.123~134 (2002)
- Mitchell, L.A., "Temperature and the cold pressor test", Journal of Pain, 5(4), pp.233~237 (2004)
- 김병조, "다양한 찬물 온도에서 손가락 추위유발성혈관확장의 재생산 반응", 항공우주기술, 9(1), pp.143~150 (2010), 한국항공우주연구원
- Krogstad, A.L., "Arteriovenous anastomoses and the thermoregulatory shift between cauaneous vasoconstrictor and vasodilator reflexes", J Auton Nerv Syst, 53, pp.215~222 (1995)
- Oberle, J, "Temperature-dependent interaction between vasoconstictor and vasodilator mechanisms in human skin", Acta Physiol Scand, 132, pp.459~469 (1988)
- Rodrigues, L., "Basal transepidermal water loss: right", left forearm difference and motoric dominance, 1998, pp.4(3), 135~137
- 배장한, "연속 가압방식의 맥파 측정방법을 위한시작점 검출 알고리즘 개발", 전자공학회논문지 - SC, 49(2), pp.46~54 (2012), 대한전자공학회
- Bae, J.H., "New Assessment Model of Pulse Depth Based on Sensor Displacement in Pulse Diagnostic Devices. Evidence-Based Complememtary and Alternative Medicine: Article ID 938641", ~ (2013)
- Elsner, R.W., "Circulation of heat to the hands of Arctic Indians", Journal of Applied Physiology, 15, pp.662~666 (1960)
- Park, W. G., "Effects of Cold Stimulation on Systemic and Local Blood Circulation(I)", The Keimyung Univ. Med. J, 2(2), pp.166~178 (1983)
- Park, W.G., "Cold Pressor Response to Seasonal Variation in Winter and Summer", The Korean Journal of Physiology, 17(2), pp.93~101 (1983)
- 임성근, "정상인의 한냉자극에 대한 심박변이도 및 도플러 초음파 혈류계를 이용한 말초 혈류관찰", 대한한의학회지, 31(2), pp.114~123 (2010), 대한한의학회
- Zaproudina, N., "Measurements of skin temperature responses to cold exposure of foot and face in healthy individuals: variability and influencing factors", Clin Physiol Funct Imaging, 31, pp.307~314 (2011)