수부냉증 진단을 위한 조갑모세혈관 혈류속도 측정 예비연구
The Role of Nail-fold Capillary Blood Velocity in Evaluating Cold Hypersensitivity in the Hands: A Pilot Study
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
This study aims to compare nail-fold capillary blood velocity (CBV) according to the presence or absence of cold hypersensitivity in the hands (CHH) using nail-fold capillaroscopy under cold stress conditions. Eleven participants were taken from the cohort study for observing long-term health status of the faculty of Semyung university. Seven of the participants displayed CHH while four showed signs of non-CHH. CBV between 0 and 60 seconds (S1) and between 240 and 300 seconds (S2) was measured under cold stress for 5 minutes, respectively, and the average value was used to compare non-CHH group and CHH group. Body mass index, Nogung (PC8) temperature and temperature difference between Nogung (PC8) and Hyeopbaek (LU4) were significantly lower in CHH group compared to non-CHH group. The S2-S1 CBV difference was negatively correlated with PC8 temperature and PC8-LU4 temperature, and positively correlated with cold pattern score and cold hypersensitivity visual analog scale. The CHH group had a lower CBV overall than non-CHH group, and the S2-S1 CBV difference was significantly higher in the CHH group than in non-CHH group. This study suggests that CBV measured by nail-fold capillarosopy might be a useful indicator of cold hypersensitivity properties.
Abstract
This study aims to compare nail-fold capillary blood velocity (CBV) according to the presence or absence of cold hypersensitivity in the hands (CHH) using nail-fold capillaroscopy under cold stress conditions. Eleven participants were taken from the cohort study for observing long-term health status of the faculty of Semyung university. Seven of the participants displayed CHH while four showed signs of non-CHH. CBV between 0 and 60 seconds (S1) and between 240 and 300 seconds (S2) was measured under cold stress for 5 minutes, respectively, and the average value was used to compare non-CHH group and CHH group. Body mass index, Nogung (PC8) temperature and temperature difference between Nogung (PC8) and Hyeopbaek (LU4) were significantly lower in CHH group compared to non-CHH group. The S2-S1 CBV difference was negatively correlated with PC8 temperature and PC8-LU4 temperature, and positively correlated with cold pattern score and cold hypersensitivity visual analog scale. The CHH group had a lower CBV overall than non-CHH group, and the S2-S1 CBV difference was significantly higher in the CHH group than in non-CHH group. This study suggests that CBV measured by nail-fold capillarosopy might be a useful indicator of cold hypersensitivity properties.
참고문헌 (36)
- Jang JB, "Study on the definition of the Female`s Part-Coldness Syndrome", J Korean Med, 15(2), pp.397~411 (1994)
- 배광호, "Perception of cold and heat pattern identification in diseases: a survey of Korean medicine doctors", Integrative Medicine Research, 6(1), pp.26~32 (2017), 한국한의학연구원[DOI]
- Bae KH, "The Relationship between Cold Hypersensitivity in the Hands and Feet and Health-Related Quality of Life in Koreans: A Nationwide Population Survey", Evid Based Complement Alternat Med, 2019, pp.6217036~ (2019)
- Bae KH, "Cold Hypersensitivity in the Hands and Feet May Be Associated with Functional Dyspepsia : Results of a Multicenter Survey Study", Evid Based Complement Alternat Med, 2016, pp.8948690~ (2016)
- Yoshino T, "Statistical analysis of hie(cold sensation)and hiesho(cold disorder)in kampo clinic", Evid Based Complement Alternat Med, 2013, pp.398458~ (2013)
- 배경미, "부인과 환자의 냉증과의 관계에 대한 조사 연구", 대한한방부인과학회지, 15(2), pp.101~113 (2002), 대한한방부인과학회
- Bae KH, "The association between cold hypersensitivity in the hands and feet and chronic disease : results of a multicentre study", BMC Complement Altern Med, 18(1), pp.40~ (2018)
- "Korean Medicine Clinical Practice Guideline for Coldness of Hands and Feet Se" (2020)[URL]
- 조준영, "적외선 체열 촬영을 이용한 수부냉증 진단의 절단값 산정", 대한한방부인과학회지, 25(3), pp.95~102 (2012), 대한한방부인과학회[DOI]
- Kim DH, "Standardization of diagnosis of cold hypersensitivity of hands and feet by D.I.T.I", J Korean Obstet Gynecol, 14(2), pp.129~134 (2001)
- 고승우, "수부냉증 진단방법에 관한 기초연구", 대한한방내과학회지, 36(3), pp.228~235 (2015), 대한한방내과학회
- 박연경, "수족냉증 환자의 HRV 특성연구", 대한한방부인과학회지, 28(1), pp.92~101 (2015), 대한한방부인과학회
- 이미주, "강남경희한방병원에 내원한 냉증을 호소하는 여성의 Heart Rate Variability 특성 연구", 대한한방부인과학회지, 24(3), pp.109~115 (2011), 대한한방부인과학회
- Pache M, "Cold feet and prolonged sleep-onset latency in vasospastic syndrome", Lancet, 358(9276), pp.125~126 (2001)
- Wang D, "Observations of upper-extremity skin temperature and corresponding overall-body thermal sensations and comfort", Building and Environment, 42(12), pp.3933~3943 (2007)
- Han JY, "Cold stress test for the diagnosis of cold hypersensitivity on hands", J of Orlental Medlcal Thermology, 2(1), pp.17~23 (2003)
- Ingegnoli F, "A systematic overview on the use and relevance of capillaroscopy in systemic sclerosis", Expert Rev Clin Immunol, 9(11), pp.1091~1097 (2013)
- 김현숙, "전신경화증의 새로운 분류기준", 대한내과학회지, 87(4), pp.395~400 (2014), 대한내과학회[DOI]
- Gasser P, "Capillary blood cell velocity in finger nailfold : characteristics and reproducibility of the local cold response", Microvasc Res, 40(1), pp.29~35 (1990)
- Cousins CC, "Resting nailfold capillary blood flow in primary open-angle glaucoma", Br J Ophthalmol, 103(2), pp.203~207 (2019)
- Jo IA, "A study on the blood flow measurement system for the diagnosis of Raynaud's phenomenon using nail-fold capillaries", pp.2012
- 배장한, "냉자극에 대한 맥율 변화 예비 연구", 동의생리병리학회지, 28(6), pp.668~673 (2014), 한의병리학회[DOI]
- Hazewinkel M., "Encyclopedia of mathematics", pp.1~ (2001)
- 배광호, "평소 증상 기반 한열변증 설문지의 신뢰도 및 타당도 연구", 동의생리병리학회지, 32(5), pp.341~346 (2018), 한의병리학회[DOI]
- Tsuboi S, "Are cold extremities an issue in women's health? Epidemiological evaluation of cold extremities among Japanese women", Int J Womens Health, 11, pp.31~39 (2019)
- Kwang-Ho Bae, "The definition and diagnosis of cold hypersensitivity in the hands and feet: Finding from the experts survey", Integrative Medicine Research, 7(1), pp.61~67 (2018), 한국한의학연구원[DOI]
- 김현숙, "류마티스 질환에서 손톱주름 모세혈관경의 임상적 유용성", 대한내과학회지, 90(6), pp.494~500 (2016), 대한내과학회[DOI]
- 김현숙, "레이노현상에서 손톱주름 모세혈관경의 유용성", 대한류마티스학회지, 22(2), pp.69~75 (2015), 대한류마티스학회
- Brown GE, "Skin capillaries in scleroderma", Archives of internal medicine, 36(1), pp.73~88 (1925)
- 이동녕, "한의표준임상진료지침 개발을 위한 수족냉증에 대한 한의사의 인식과 치료현황", 대한한방부인과학회지, 30(3), pp.92~116 (2017), 대한한방부인과학회[DOI]
- 김경철, "인체를 대상으로 하는 血虛 血瘀證 모델 개발을 위한 손톱 주름살의 모세혈관에 대한 영상장치 연구(Ⅰ)", 동의생리병리학회지, 18(3), pp.789~791 (2004), 한의병리학회
- 김구, "설문지와 의료기기 자료 분석을 통한 사상체질별 피로 특성 연구", 사상체질의학회지, 25(4), pp.306~319 (2013), 사상체질의학회[DOI]
- Cankar K, "Gender differences in cutaneous vascular and autonomic nervous response to local cooling", Clin Auton Res, 13(3), pp.214~220 (2003)
- Coffman JD, "Total and capillary fingertip blood flow in Raynaud's phenomenon", N Engl J Med, 285(5), pp.259~263 (1971)
- Bartelink ML, "A standardized finger cooling test for Raynaud's phenomenon : diagnostic value and sex differences", European heart journal, 14(5), pp.614~622 (1993)
- Cutolo M, "Raynaud's phenomenon and the role of capillaroscopy", Arthritis Rheum, 48(11), pp.3023~3030 (2003)
