Effcacy and Safety of Lumen-Apposing Stents for Management of Pancreatic Fluid Collections in a Community Hospital Setting
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Background/Aims: Endoscopic ultrasound-guided transmural drainage and necrosectomy employing lumen-apposing metal stent(LAMS) are used for treating pancreatic fluid collections (PFCs) with excellent results from academic centers. Herein, we report theeffcacy and safety of LAMS in the treatment of PFCs at a community hospital. Methods: We retrospectively reviewed the etiology of pancreatitis, type and size of PFCs, length of procedure, technical success,clinical success, adverse events, and stent removal. The primary outcome was the rate of clinical success, and secondary outcomes weretechnical success and adverse events. Results: Twenty-seven patients with a mean age of 54.1±6.5 years were included, 44% of which were men. The mean size of the PFCswas 9.7±5.0 cm (range, 3–21). The most common etiology of pancreatitis was alcohol (44%) followed by idiopathic causes (30%) andpresence of gallstones (22%). The diagnosis was pseudocyst in 44.4% (12/27) and walled off necrosis in 55.6% (15/27) of patients. Therewas 100% technical success without any complications. Clinical success was achieved in 22 of 27 patients (81.5%) who underwent stentremoval. Conclusions: Our study is the first to report that endoscopic therapy of PFCs using LAMS is safe and effective even in a communityhospital setting with limited resources and support compared to large academic centers.
Abstract
Background/Aims: Endoscopic ultrasound-guided transmural drainage and necrosectomy employing lumen-apposing metal stent(LAMS) are used for treating pancreatic fluid collections (PFCs) with excellent results from academic centers. Herein, we report theeffcacy and safety of LAMS in the treatment of PFCs at a community hospital. Methods: We retrospectively reviewed the etiology of pancreatitis, type and size of PFCs, length of procedure, technical success,clinical success, adverse events, and stent removal. The primary outcome was the rate of clinical success, and secondary outcomes weretechnical success and adverse events. Results: Twenty-seven patients with a mean age of 54.1±6.5 years were included, 44% of which were men. The mean size of the PFCswas 9.7±5.0 cm (range, 3–21). The most common etiology of pancreatitis was alcohol (44%) followed by idiopathic causes (30%) andpresence of gallstones (22%). The diagnosis was pseudocyst in 44.4% (12/27) and walled off necrosis in 55.6% (15/27) of patients. Therewas 100% technical success without any complications. Clinical success was achieved in 22 of 27 patients (81.5%) who underwent stentremoval. Conclusions: Our study is the first to report that endoscopic therapy of PFCs using LAMS is safe and effective even in a communityhospital setting with limited resources and support compared to large academic centers.
참고문헌 (21)
- Banks PA, "Classification of acute pancreatitis--2012 : revision of the Atlanta classification and definitions by international consensus", Gut, 62, pp.102~111 (2013)
- Varadarajulu S, "Equal efficacy of endoscopic and surgical cystogastrostomy for pancreatic pseudocyst drainage in a randomized trial", Gastroenterology, 145, pp.583~590.e1 (2013)
- Varadarajulu S, "Prospective randomized trial comparing EUS and EGD for transmural drainage of pancreatic pseudocysts(with videos)", Gastrointest Endosc, 68, pp.1102~1111 (2008)
- Park DH, "Endoscopic ultrasound-guided versus conventional transmural drainage for pancreatic pseudocysts : a prospective randomized trial", Endoscopy, 41, pp.842~848 (2009)
- Mohan BP, "Adverse events with lumen-apposing metal stents in endoscopic gallbladder drainage : a systematic review and meta-analysis", Endosc Ultrasound, 8, pp.241~248 (2019)
- Mohan BP, "Efficacy and safety of endoscopic ultrasound-guided choledochoduodenostomy : a systematic review and meta-analysis", J Clin Gastroenterol, 53, pp.243~250 (2019)
- Mohan BP, "Lumen-apposing metal stents, fully covered self-expanding metal stents, and biodegradable stents in the management of benign of GI strictures : a systematic review and meta-analysis", J Clin Gastroenterol, 53, pp.560~573 (2019)
- Cotton PB, "A lexicon for endoscopic adverse events : report of an ASGE workshop", Gastrointest Endosc, 71, pp.446~454 (2010)
- Siddiqui AA, "EUS-guided drainage of peripancreatic fluid collections and necrosis by using a novel lumen-apposing stent : a large retrospective, multicenter U. S. experience(with videos)", Gastrointest Endosc, 83, pp.699~707 (2016)
- Vila JJ, "Pancreatic pseudocyst drainage guided by endoscopic ultrasound", World J Gastrointest Endosc, 2, pp.193~197 (2010)
- Siddiqui AA, "Outcomes of EUS-guided drainage of debris-containing pancreatic pseudocysts by using combined endoprosthesis and a nasocystic drain", Gastrointest Endosc, 78, pp.589~595 (2013)
- Tyberg A, "Management of pancreatic fluid collections : a comprehensive review of the literature", World J Gastroenterol, 22, pp.2256~2270 (2016)
- Ali Alali, "Endoscopic Ultrasound-Guided Management of Pancreatic Fluid Collections: Update and Review of the Literature", Clinical Endoscopy, 50(2), pp.117~125 (2017), 대한소화기내시경학회
- Rinninella E, "EUS-guided drainage of pancreatic fluid collections using a novel lumen-apposing metal stent on an electrocautery-enhanced delivery system : a large retrospective study(with video)", Gastrointest Endosc, 82, pp.1039~1046 (2015)
- Puga M, "Safety of lumen-apposing stent with or without coaxial plastic stent for endoscopic ultrasound-guided drainage of pancreatic fluid collections : a retrospective study", Endoscopy, 50, pp.1022~1026 (2018)
- Garcia-Alonso FJ, "Cumulative risks of stent migration and gastrointestinal bleeding in patients with lumen-apposing metal stents", Endoscopy, 50, pp.386~395 (2018)
- Chandran S, "Management of pancreatic collections with a novel endoscopically placed fully covered self-expandable metal stent : a national experience(with videos)", Gastrointest Endosc, 81, pp.127~135 (2015)
- Bang JY, "Lumen-apposing metal stents(LAMS)for pancreatic fluid collection(PFC)drainage : may not be business as usual", Gut, 66, pp.2054~2056 (2017)
- Siddiqui AA, "Fully covered self-expanding metal stents versus lumen-apposing fully covered self-expanding metal stent versus plastic stents for endoscopic drainage of pancreatic walled-off necrosis : clinical outcomes and success", Gastrointest Endosc, 85, pp.758~765 (2017)
- Aburajab M, "Safety and efficacy of lumen-apposing metal stents with and without simultaneous double-pigtail plastic stents for draining pancreatic pseudocyst", Gastrointest Endosc, 87, pp.1248~1255 (2018)
- Chen YI, "Cost-effectiveness analysis comparing lumen-apposing metal stents with plastic stents in the management of pancreatic walled-off necrosis", Gastrointest Endosc, 88, pp.267~276.e1 (2018)
