궤양성 대장염에 합병된 Budd-Chiari 증후군 및 대장암 1예
A Case of Chronic Ulcerative Colitis Complicated by Budd-Chiari Syndrome and Colon Cancer
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초록
궤양성 대장염은 만성적인 대장에 염증성 질환으로 많은 장내 및 장외 합병증을 가진다. 장내 합병증 중 대장암은 유병기간 및 침범부위에 따라 발병 위험이 증가하며, 장외 합병증으로 혈전색전성 질환을 동반할 수 있다. 혈전색전 합병증은 대부분 심부 정맥이나 폐에 발생하며 드물게는 장간막, 뇌정맥 등에 발생할 수 있다. 그러나 간정맥을 침범해 Budd-Chiari 증후군을 일으킨 경우는 세계적으로 드물며 국내에는 보고가 없다. 저자들은 10년 이상의 병력을 가진 궤양성 대장염 환자에서 대장암 및 Budd-Chiari 증후군을 동반한 1예를 경험하였기에 보고하는 바이다.
Abstract
Ulcerative colitis is a chronic inflammatory bowel disease and may have many intestinal and extraintestinal complications. Compared with general population, patients with longstanding ulcerative colitis have an increased risk of colorectal cancer. Patients with ulcerative colitis have an increased frequency of thromboembolism too. However, hepatic vein thrombosis is a very rare extraintestinal complication. This is the first reported case of a young patient with ulcerative colitis who developed synchronous colonic neoplasm and chronic Budd-Chiari syndrome manifested as esophageal variceal bleeding. We report a case of ulcerative colitis complicated by Budd-Chiari syndrome and colon cancer in a 28-year-old female.
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