다발성 점막하 병변으로 발현한 직장의 기저양 편평 세포암 1예
Basaloid Squamous Cell Carcinoma of the Rectum Manifesting as Multiple Submucosal Lesions
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초록
기저양 편평세포암은 편평세포암의 미분화 변종으로 주로 혀, 인두, 후두, 기관, 식도와 같은 상부호흡소화기에서 발생하며, 폐, 자궁경부, 흉선, 항문 등 다양한 부위에서 발생한다. 항문 외의 장관에서 발생하는 경우 총배설강적 태생 잔유세포(cloacogenic embryologic rests), 편평 화생 상피(squamous metaplastic epithelium), 다기능성 기저세포(totipotential basal cell)에서 발생한다고 알려져 있으며 직장에서 발견된 예는 국내에서는 보고된 바가 없다. 저자들은 복통과 혈액 흔적 대변을 주소로 내원한 43세 남자에서 직장에 다발성 점막하 병변의 형태로 발현한 기저양 편평세포암을 경험하였기에 관련 문헌고찰과 함께 보고한다.
Abstract
Basaloid squamous carcinoma is a rare, pooly differentiated variant of squamous cell carcinoma. It occurs in various sites, including the upper digestive tract, the esophagus, lung, anus, cervix and thymus. It has been postulated that basaloid carcinoma may arise from outside of the anal canal, such as at where the cloacogenic embryologic cells rest, the squamous metaplastic epithelium, or the totipotential basal cells. This tumor is a distinct entity that should be carefully distinguished from basal cell carcinomas of the anal canal, which is a condition that has a very good prognosis, and anal or perianal squamous cell carcinomas, which have a different path of spread and they vary considerably in their behavior. We report here on a patient with basaloid squamous carcinoma in the distal rectum that manifested as multiple submucosal lesions, and the patient presented with abdominal pain and blood tinged stool. (Korean J Gastrointest Endosc 2006;33:168-172)
참고문헌 (18)
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