위장관 출혈을 동반한 위의 상피양 세포형 위장관 간질종양 1예
A Case of Epithelioid Type Gastric Gastrointestinal Stromal Tumor with Gastrointestinal Bleeding
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초록
위장관 간질종양의 50～60%가 위에서 발생하며, 종괴를 구성하는 세포형에 따라서 방추형 세포형, 상피양 세포형 또는 혼합형으로 분류된다. 저자들은 위장관 출혈을 보인 60세 남자에서 상부위장관 내시경검사로 출혈성 궤양을 동반하는 위 점막하 종양을 관찰하고, 수술로 제거하여 면역조직화학 염색에서 CD117 양성인 상피양 세포형 위장관 간질종양으로 진단하였다. 국내에서는 비교적 드문 위장관 출혈을 동반한 위장관 간질종양의 아형을 경험하여 문헌고찰과 함께 보고한다.
Abstract
The stomach is the most frequently noted site (50∼60%) of gastrointestinal stromal tumor. This tumor is categorized into three subtypes (the spindle cell type, the epithelioid type or mixed type) according to the shape of the cells that make up the tumor. We herein report on a case of gastrointestinal stromal tumor with an epithelioid subtype in a 60-year-old male. On admission, the patient presented with epigastric pain and melena. Endoscopy revealed a submucosal tumor with a central ulcer at the gastric body. Gastric wedge resection was performed. The tumor cells showed a rounded shape and positive staining for CD117. Because the epithelioid type gastrointestinal stromal tumor is unusual in Korea, we report here on this case along with a review of the relevant literature. (Korean J Gastrointest Endosc 2007;35:87-90)
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