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논문KCI 등재

중간대뇌동맥과 두개외 속목동맥의 급성 일렬폐색에 의한 초급성 뇌경색 환자에서 성공적인 혈관내 물리적 혈전제거치료 성공 증례

Successful Endovascular Mechanical Thrombolysis in a Patient with Hyperacute Tandem Occlusions of Middle Cerebral Artery and Extracranial Internal Carotid Artery

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Previous studies have shown that patients with tandem occlusions involving extracranial internal carotid artery (ICA) and middle cerebral artery (MCA) have lower likelihood of recanalization by standard intravenous thrombolytic therapy. A 70-years-old man with a history of hypertension was admitted because of left hemiplegia and drowsiness which developed 47 minutes ago. On neurologic examination, he was drowsy and showed neglect syndrome as well as left hemiplegia. Brain CT angiography showed tandem occlusions at right extracranial ICA and proximal MCA. The administration of intravenous (IV) tissue plasminogen activator (tPA) did not improve his symptoms. We performed angioplasty and stenting for proximal ICA occlusion followed by mechanical thrombolysis for MCA occlusion. After the endovascular treatment, the MCA was recanalized and the patient recovered to show only mild left side weakness. This case shows successful treatment of hyperacute ischemic infarction from tendem occlusion of right MCA and proximal ICA with endovascular treatment following IV tPA thrombolysis. (Korean J Stroke 2011;13:147-151)

Abstract

Previous studies have shown that patients with tandem occlusions involving extracranial internal carotid artery (ICA) and middle cerebral artery (MCA) have lower likelihood of recanalization by standard intravenous thrombolytic therapy. A 70-years-old man with a history of hypertension was admitted because of left hemiplegia and drowsiness which developed 47 minutes ago. On neurologic examination, he was drowsy and showed neglect syndrome as well as left hemiplegia. Brain CT angiography showed tandem occlusions at right extracranial ICA and proximal MCA. The administration of intravenous (IV) tissue plasminogen activator (tPA) did not improve his symptoms. We performed angioplasty and stenting for proximal ICA occlusion followed by mechanical thrombolysis for MCA occlusion. After the endovascular treatment, the MCA was recanalized and the patient recovered to show only mild left side weakness. This case shows successful treatment of hyperacute ischemic infarction from tendem occlusion of right MCA and proximal ICA with endovascular treatment following IV tPA thrombolysis. (Korean J Stroke 2011;13:147-151)

참고문헌 (7)

  1. Rubiera M, "Tandem internal carotid artery", middle cerebral artery occlusion: an independent predictor of poor outcome after systemic thrombolysis, 2006, pp.37, 2301~2305
  2. Kim YS, "Early recanalization rates and clinical outcomes in patients with tandem internal carotid artery", middle cerebral artery occlusion and isolated middle cerebral artery occlusion, 2005, pp.36(4), 869~871
  3. Jovin TG, "Emergent stenting of extracranial internal carotid artery occlusion in acute stroke has a high revascularization rate", Stroke, 36, pp.2426~2430 (2005)
  4. Malik AM, "Endovascular treatment of tandem extracranial", intracranial anterior circulation occlusions: preliminary single-center experience, 2011, pp.42, 1653~1657
  5. Jovin TG, "Pretreatment ipsilateral regional cortical blood fl ow infl uences vessel recanalization in intra-arterial thrombolysis for MCA occlusion", AJNR Am J Neuroradiol, 28, pp.164~167 (2007)
  6. Kim DJ, "Intraarterial thrombolytic therapy for hyperacute ischemic stroke caused by tandem occlusion", Cerebrovasc Dis, 26, pp.184~189 (2008)
  7. Chimowitz MI, "SAMMPRIS Trial Investigators. Stenting versus aggressive medical therapy for intracranial arterial stenosis", N Engl J Med, 365, pp.993~1003 (2011)

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