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당뇨병성 케톤산증으로 발현된 갑상선 기능항진증 1예

A case of hyperthyroidism presented as diabetic ketoacidosis

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초록

당뇨병성 케톤산 혈증은 당뇨병 발생 자체, 감염, 부적절한 인슐린 투여 및 중단이 흔한 원인으로 보고되어 있다. 저자들은 제1형 당뇨병 환자에게서 위의 유발인자 없이 갑상선 항진증에 의해 유발된 당뇨병성 케톤산증의 1예를 경험하였기에 이를 문헌고찰과 함께 보고하는 바이다.

Abstract

Diabetic ketoacidosis is an acute complication of diabetic mellitus. The most common triggering factors are infection, insulin therapy omission and the onset of the disease, but if these are excluded, other less frequent etiologic factors must be ruled out. We report a case of 22-year-old woman with Graves' disease presented as diabetic ketoacidosis. She was diagnosed type 1 diabetes mellitus at 13 years old and continually has been treated with insulin therapy until now. She typically showed tachycardia at rest in spite of correction of metabolic acidosis. Hyperthyroidism worsens glycemic control in diabetic patients and may precipitate diabetic ketoacidosis. Hyperthyroidism always should be investigated in diabetic patients presenting diabetic ketoacidosis without obvious triggering factors.

참고문헌 (15)

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  2. "Diabetic ketoacidosis precipitated by thyrotoxicosis", 75, pp.291~292 (1999)
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  4. "Diabetic ketoacidosis", 345, pp.767~772 (1995)
  5. "Diabetic ketoacidosis:its cause and their prevention", 2, pp.825~829 (1968)
  6. "HLA-DQB1-associated susceptibility that distinguished Hashimoto's thyroiditis from Graves' disease in type I diabetic patients", 78, pp.878~883 (1994)
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  8. "Pancreatic islet cell antibodies in diabetic mellitus correlated with the duration and type of diabetes", pp.138~26 147 (1977)
  9. "Multiple immunological abnormalities in patients with type 1", (tkins al), pp.132~30 143 (1987)
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  12. "The effect of streptozotocin- induced diabetes on the pituitary-thyroid axis in goitrogen-treated rats", 86, pp.128~139 (1977)
  13. "Thyroid hormones in insulin requiring diabetes before and after treatment", 15, pp.29~32 (1978)
  14. "Thyrotoxicosis without elevated serum triiodothyronine levels during diabetic ketoacidosis", 140, pp.408~410 (1980)
  15. "Hyperthyroidism and diabetes mellitus:an analysis of 70 patients", 140, pp.370~373 (1980)

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