Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature
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The full-thickness resection device (FTRD) is a novel endoscopic device approved for the resection of colorectal lesions. This case-seriesdescribes the device and its use in high-risk patients with colorectal lesions and provides an overview of the potential indications inrecently published data. Between December 2014 and September 2015, 3 patients underwent endoscopic full thickness resection using the FTRD for colorectallesions: 1 case for a T1 adenocarcinoma in the region of a surgical anastomosis after recto-sigmoidectomy, 1 case for a non-liftingcolonic adenoma with low-grade dysplasia in an 89-year old patient and 1 for a recurrent adenoma with high-grade dysplasia in ayoung patient with ulcerative rectocolitis who was under immunosuppression after renal transplantation. Both technical and clinicalsuccess rates were achieved in all cases. The size of removed lesions ranged from 9 to 30 mm. Overall, the most frequent indication in the literature has been for lifting or non-lifting adenoma, submucosal tumors, neuroendocrintumors, incomplete endoscopic resection (R1) or T1 carcinoma. Colorectal FTRD is a feasible technique for the treatment of colorectal lesions and represents a minimally invasive alternative for eithersurgical or conventional endoscopic resection strategies.
Abstract
The full-thickness resection device (FTRD) is a novel endoscopic device approved for the resection of colorectal lesions. This case-seriesdescribes the device and its use in high-risk patients with colorectal lesions and provides an overview of the potential indications inrecently published data. Between December 2014 and September 2015, 3 patients underwent endoscopic full thickness resection using the FTRD for colorectallesions: 1 case for a T1 adenocarcinoma in the region of a surgical anastomosis after recto-sigmoidectomy, 1 case for a non-liftingcolonic adenoma with low-grade dysplasia in an 89-year old patient and 1 for a recurrent adenoma with high-grade dysplasia in ayoung patient with ulcerative rectocolitis who was under immunosuppression after renal transplantation. Both technical and clinicalsuccess rates were achieved in all cases. The size of removed lesions ranged from 9 to 30 mm. Overall, the most frequent indication in the literature has been for lifting or non-lifting adenoma, submucosal tumors, neuroendocrintumors, incomplete endoscopic resection (R1) or T1 carcinoma. Colorectal FTRD is a feasible technique for the treatment of colorectal lesions and represents a minimally invasive alternative for eithersurgical or conventional endoscopic resection strategies.
참고문헌 (14)
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