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알레르기비염의 진단과 치료

Diagnosis and treatment of allergic rhinitis

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초록

The diagnosis of allergic rhinitis can generally be made on the basis of the history and physical examination. The history helps establish seasonality, potentially inciting factors, and co-morbidities including sinusitis, nasal polyps, allergic conjunctivitis, and asthma. On physical examination, the nasal mucous membranes are pale, wet, and boggy. Allergy testing is performed in order to confirm the diagnosis and which allergens are relevant to the symptoms. The management of allergic rhinitis includes allergen avoidance, pharmacologic treatment, and specific immunotherapy. Mild symptoms are easily controlled with either a second-generation antihistamine or a nasal corticosteroid alone. For patients with moderate-to-severe symptoms with nasal congestion as a predominant finding, therapy should be started with daily use of a nasal corticosteroid, which would be combined with other medications, such as antihistamines and decongestants. Specific immunotherapy is generally reserved for the selected patients whose symptoms are inadequately controlled with a pharmacotherapy and allergen avoidance.

Abstract

The diagnosis of allergic rhinitis can generally be made on the basis of the history and physical examination. The history helps establish seasonality, potentially inciting factors, and co-morbidities including sinusitis, nasal polyps, allergic conjunctivitis, and asthma. On physical examination, the nasal mucous membranes are pale, wet, and boggy. Allergy testing is performed in order to confirm the diagnosis and which allergens are relevant to the symptoms. The management of allergic rhinitis includes allergen avoidance, pharmacologic treatment, and specific immunotherapy. Mild symptoms are easily controlled with either a second-generation antihistamine or a nasal corticosteroid alone. For patients with moderate-to-severe symptoms with nasal congestion as a predominant finding, therapy should be started with daily use of a nasal corticosteroid, which would be combined with other medications, such as antihistamines and decongestants. Specific immunotherapy is generally reserved for the selected patients whose symptoms are inadequately controlled with a pharmacotherapy and allergen avoidance.

참고문헌 (25)

  1. Blaiss MS, "Rhinitis-asthma connection: epidemiologic and pathophysiologic basis", Allergy Asthma Proc, 26, pp.35~40 (2005)
  2. Bousquet J, "Heterogeneity of atopy. I. Clinical and immunologic characteristics of patients allergic to cypress pollen", Allergy, 48, pp.183~188 (1993)
  3. Dixon AE, "Allergic rhinitis and sinusitis in asthma: differential effects on symptoms and pulmonary function", Chest, 130, pp.429~435 (2006)
  4. Burgess JA, "Childhood adiposity predicts adult-onset current asthma in females: a 25-yr prospective study", Eur Respir J, 29, pp.668~675 (2007)
  5. Settipane RA, "Epidemiology of rhinitis: allergic and nonallergic", Clin Allergy Immunol, 19, pp.23~34 (2007)
  6. Wallace DV, "The diagnosis and management of rhinitis: An updated practice parameter documents of the Joint Task Force on Practice Parameters in Allergy, Asthma and Immunology", J Allergy Clin Immunol, 122, pp.S1~s84 (2008)
  7. Bousquet J, "Allergic rhinitis and its impact on asthma", J Allergy Clin Immunol, 108(5), pp.S147~S334 (2001)
  8. Petersson G, "Clinical history, skin prick test and RAST in the diagnosis of birch and timothy pollinosis", Allergy, 41, pp.398~407 (1986)
  9. Crobach M, "Nasal smear eosinophilia for the diagnosis of allergic rhinitis and eosinophilic non-allergic rhinitis", Scand J Prim Health Care, 14, pp.116~121 (1996)
  10. Dykewicz MS, "Diagnosis and management of rhinitis: complete guidelines of the Joint Task Force on Practice Parameters in Allergy, Asthma and Immunology. American Academy of Allergy, Asthma, and Immunology", Ann Allergy Asthma Immunol, 81(2), pp.478~518 (1998)
  11. Wheeler PW, "Vasomotor rhinitis", Am Fam Physician, 72, pp.1057~1062 (2005)
  12. Sheikh A, "House dust mite avoidance measures for perennial allergic rhinitis", Cochrane Database Syst Rev, 4, pp.CD001563~ (2001)
  13. Hindmarch I, "Psychometric aspects of antihistamines", Allergy, 50, pp.48~54 (1995)
  14. Moneret-Vautrin DA, "Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs", Eur Ann Allergy Clin Immunol, 38, pp.347~350 (2006)
  15. Berger W, "Impact of azelastine nasal spray on symptoms and quality of life compared with cetirizine oral tablets in patients with seasonal allergic rhinitis", Ann Allergy Asthma Immunol, 97, pp.375~381 (2006)
  16. Corren J, "Effectiveness of azelastine nasal spray compared with oral cetirizine in patients with seasonal allergic rhinitis", Clin Ther, 27, pp.543~553 (2005)
  17. Yanez A, "Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systemic review with meta-analysis", Ann Allergy Asthma immunol, 89, pp.479~484 (2002)
  18. Derendorf H, "Molecular and clinical pharmacology of intranasal corticosteroids: clinical and therapeutic implications", Allergy, 63, pp.1292~1300 (2008)
  19. Corren J, "Intranasal corticosteroids for allergic rhinitis: how do different agents compare?", J Allergy Clin Immunol, 104, pp.S144~S149 (1999)
  20. Weiner JM, "Intranasal corticosteroids versus oral H1 receptor antagonists in allergic rhinitis: systemic review of randomized controlled trials", BMJ, 317, pp.1624~1629 (1998)
  21. Wilson AM, "Leukotriene receptor antagonists for allergic rhinitis: a systematic review and meta-analysis", Am J Med, 116, pp.338~344 (2004)
  22. van Cauwenberge P, "Consensus statement on the treatment of allergic rhinitis. European Academy of Allergology and Clinical Immunology", Allergy, 55, pp.116~134 (2000)
  23. Cox L, "Allergen immunotherapy: a practice parameter second update", J Allergy Clin Immunol, 120, pp.S25~S85 (2007)
  24. Calderon MA, "Allergen injection immunotherapy for seasonal allergic rhinitis", Cochrane Database Syst Rev, pp.CD001936~ (2007)
  25. Cox L, "Sublingual immunotherapy and allergic rhinitis", Curr Allergy Asthma Rep, 8, pp.102~110 (2008)

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