췌장 선방세포암 1예
A case of acinar cell carcinoma of the pancreas
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초록
최근 저자들은 매우 드문 종양인 췌장 선방세포암으로 근치적 원위부 췌장절제술과 비장절제술 시행 후 위의 단독 재발로 위전절제술과 다발성 간전이로 좌간절제술 후 보존적 capecitabine 항암화학요법을 실시하여 장기간 종양의 진행이 없는 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.
Abstract
Acinar cell carcinoma of the pancreas is a rare tumor that constitutes 1~2% of all pancreatic cancers. The clinical and radiologic findings are inconclusive when diagnosing this disease. Acinar cell carcinoma progresses rapidly and metastasizes early, resulting in a poor prognosis. A 41-year-old man was admitted for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography (PET)-CT showed a splenic mass involving the pancreatic tail with increased 18F-fluorodeoxyglucose (18F-FDG) uptake. A primary radical distal pancreatectomy and splenectomy were carried out. The pathology revealed acinar cell carcinoma of the pancreas. Three months later, a gastric recurrence was detected and a total gastrectomy was performed. Four months later, multiple hepatic metastases were found and a left hepatectomy was carried out. During treatment with capecitabine, no evidence of tumor progression was observed for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma that did not progress for 14 months with capecitabine treatment.
참고문헌 (14)
- Klimastra DS, "Acinar cell carcinoma of the pancreas: a clinicopathologic study of 28 cases", Am J Surg Pathol, 16, pp.815~837 (1992)
- Webb JN, "Acinar cell neoplasm of the exocrine pancreas", J Clin Pathol, 30, pp.103~112 (1977)
- Kim MC, "Clinical study of acinar cell carcinomas of the pancreas: our 5 cases and a review of 5 cases reported in Korea", J Korean Surg Soc, 60, pp.97~102 (2001)
- Kuopio T, "Acinar cell carcinoma of the pancreas: report of three cases", APMIS, 103, pp.69~78 (1995)
- Lee SH, "Acinar cell carcinoma of the pancreas: a case report", J Korean Radiol Soc, 39, pp.1181~1183 (1998)
- Oh JY, "CT findings of acinar cell carcinoma of the pancreas: focused on spiral CT findings", J Korean Radiol Soc, 45, pp.29~34 (2001)
- Stafford-Johnson DB, "Dual phase helical CT of non-functioning islet cell tumors", J Comput Assist Tomogr, 22, pp.335~339 (1998)
- van Hoe L, "Helical CT for the preoperative localization of islet cell tumors of the pancreas: value of arterial and parenchymal phase images", AJR Am J Roentgenol, 165, pp.1437~1439 (1995)
- Chen J, "Morphological study of 391 cases of exocrine pancreatic tumors with special reference to the classification of exocrine pancreatic carcinoma", J Pathol, 146, pp.17~29 (1985)
- Halpert B, "A retrospective study of 120 patients with carcinoma of the pancreas", Surg Gynecol Obstet, 121, pp.91~96 (1965)
- Moldow RE, "Epidemiology of pancreatic cancer in Connecticut", Gastroenterology, 55, pp.677~686 (1968)
- Morohoshi T, "Clinicopathological features and diagnostic points of uncommon pancreatic tumors", Rinsho Byori, 42, pp.143~149 (1994)
- Holen KD, "Clinical characteristics and outcomes from an institutional series of acinar cell carcinoma of the pancreas and related tumors", J Clin Oncol, 20, pp.4673~4678 (2002)
- Lee JL, "Locally advanced acinar cell carcinoma of the pancreas successfully treated by capecitabine and concurrent radiotherapy: report of two cases", Pancreas, 27, pp.e18~e22 (2003)