허혈뇌졸중에서 경동맥 내막-중막 두께와 뇌졸중위험인자와의 관계
Association between Carotid Artery Intima-Media Thickness and Stroke Risk Factors in Ischemic Stroke
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Background: Common carotid artery intima-media thickness (IMT) is an accepted sonographic marker of early atherosclerosis,and increased IMT represents a risk of ischemic stroke. The purpose of this study was to evaluate the correlation between common carotid artery IMT and stroke risk factors in patients with ischemic stroke. Methods: Subjects were 381 patients with acute ischemic stroke. High resolution B-mode ultrasonography was performed to measure IMT at common carotid artery. Multivariate regression analysis was performed to determine the independent factors related to common carotid artery IMT. Results: The variables that strongly predicted an increase in the common carotid artery IMT were age (P <0.001) and diabetes mellitus(P <0.001). Conclusion: Increased common carotid artery IMT is independently associated with age and diabetes mellitus in patients with ischemic stroke. (Korean J Stroke 2011;13:129-133)
Abstract
Background: Common carotid artery intima-media thickness (IMT) is an accepted sonographic marker of early atherosclerosis,and increased IMT represents a risk of ischemic stroke. The purpose of this study was to evaluate the correlation between common carotid artery IMT and stroke risk factors in patients with ischemic stroke. Methods: Subjects were 381 patients with acute ischemic stroke. High resolution B-mode ultrasonography was performed to measure IMT at common carotid artery. Multivariate regression analysis was performed to determine the independent factors related to common carotid artery IMT. Results: The variables that strongly predicted an increase in the common carotid artery IMT were age (P <0.001) and diabetes mellitus(P <0.001). Conclusion: Increased common carotid artery IMT is independently associated with age and diabetes mellitus in patients with ischemic stroke. (Korean J Stroke 2011;13:129-133)
참고문헌 (19)
- Pignoli P, "Intima plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging", Circulation, 74, pp.1399~1406 (1986)
- Aminbakhsh A, "Carotid intima-media thickness measurements: what defines an abnormality? A systemic review", Clin Invest Med, 4, pp.149~157 (1999)
- Bots M, "Common carotid intima-media thickness and risk of stroke and myocardia infarction (The Rotterdam study)", Circulation, 96, pp.1432~1437 (1997)
- Lorenz MW, "Prediction of clinical cardiovascular events with carotid intima-media thickness: a systemic review and meta-analysis", Circulation, 115, pp.459~467 (2007)
- Chambless LE, "Association of transient ischemic attack", stroke symptoms assessed by standardized questionnaire and algorithm with cerebrovascular risk factors and carotid artery wall thickness. The ARIC study 1987-1989, 1996, pp.144, 857~866
- Touboul PJ, "Common carotid artery intima-media thickness and brain infarction: the Etude du Profi l Génétique de l’Infarctus Cérébral (GENIC) casecontrol study", Circulation, 102, pp.313~318 (2000)
- de Burgos-Lunar C, "Validation of diabetes mellitus and hypertension diagnosis in computerized medical records in primary health care", BMC Med Res Methodol, 11, pp.146~156 (2011)
- Bonithon-Kopp C, "Risk factors for early carotid atherosclerosis in middle-aged French women", Arterioscler Thromb, 11, pp.966~972 (1991)
- Simon A, "Intimamedia thickness: a new tool for diagnosis and treatment of cardiovascular risk", J Hypertens, 20, pp.159~169 (2002)
- Bots ML, "Cerebral white matter lesions and atherosclerosis in the Rotterdam study", Lancet, 341, pp.1232~1237 (1993)
- Kim CS, "Normative values of carotid artery intima-media thickness in healthy Korean adults and estimation of macrovascular diseases relative risk using this data in type 2 diabetes patients", Diabetes Res Clin Pract, 72, pp.183~189 (2006)
- Ando F, "Ultrasonic evaluation of common carotid intima-media thickness(IMT): infl uence of local plaque on the relationship between IMT and age", J Epidemiol, 10, pp.S10~17 (2000)
- Depairon M, "Reference values of intima-media thickness of carotid and femoral arteries in subjects aged 20 to 60 years and without cardiovascular risk factors", Arch Mal Coeur Vaiss, 93, pp.721~726 (2000)
- Distiller LA, "Carotid artery intima-media complex thickening in patients with relatively long-surviving type 1 diabetes mellitus", J Diabetes Complications, 20, pp.280~284 (2006)
- de Freitas EV, "Study of the intima-media thickening in carotid arteries of healthy elderly with high blood pressure and elderly with high blood pressure and dyslipidemia", Clin Interv Aging, 3, pp.525~534 (2008)
- Gariepy J, "Sex and topographic differences in associations between large artery wall thickness and coronary risk profi le in a French working cohort: the AXA study", Arterioscler Thromb Vasc Biol, 4, pp.584~590 (1998)
- Lee EJ, "Relevance of common carotid intima-media thickness and carotid plaque as risk factors for ischemic stroke in patients with type 2 diabetes mellitus", AJNR Am J Neuroradiol, 28, pp.916~919 (2007)
- Markus RA, "Influence of lifestyle modifi cation on atherosclerotic progression determined by ultrasonographic change in the common carotid intima-media thickness", Am J Clin Nutr, 65, pp.1000~1004 (1997)
- Preston E, "Association between carotid artery intima-media thickness and cardiovascular risk factors in CKD", Am J Kidney Dis, 46, pp.856~862 (2005)
