본문 바로가기
KERD
논문KCI 등재

미분화 암종이 동반된 췌장의 파골세포 모양 거대세포종양 1예

A case of undifferentiated carcinoma with osteoclast-like giant cells of the pancreas

2

조회

0

다운로드

2

인용

0

참고문헌

키워드

주제분류내과학

초록

본 증례는 췌장의 미부에 발생한 미분화 암종이 동반된 파골세포 모양 거대세포종양의 증례이며 림프절 전이나 원격전이를 보이지 않아 근치적 절제를 시행할 수 있었고, 보조항암화학요법을 이용하여 치료 중이어서 질환에 관한 고찰 및 국내 증례들을 종합하여 보고하는 바이다.

Abstract

An osteoclast-like giant cell tumor of the pancreas is a very rare neoplasm, with only three cases reported in Korea. Due to the rarity of this tumor type, few clinical data are available. We present a case of undifferentiated carcinoma with osteoclast-like giant cell tumor arising in the tail of the pancreas in a 72-year-old woman hospitalized to evaluate epigastric pain and a palpable abdominal mass. Magnetic resonance imaging revealed the presence of a large enhancing mass with septation arising from the tail of the pancreas. A distal pancreatectomy with splenectomy was performed. The pathological diagnosis was undifferentiated carcinoma with osteoclast-like giant cell tumor. Here, we describe the histopathological and immunohistochemical findings and review the clinical features of the cases reported in the Korean literature.

참고문헌 (13)

  1. Dworak O, "Osteoclastic giant cell tumor of the pancreas: an immunohistological study and review of the literature", Pathol Res Pract, 189, pp.228~231 (1993)
  2. Rosai J, "Carcinoma of pancreas simulating giant cell tumor of bone: electron-microscopic evidence of its acinar cell origin", Cancer, 22, pp.333~344 (1968)
  3. 조상형, "췌장의 파골세포 모양 거대세포종양 1예", 대한소화기학회지, 45(6), pp.441~445 (2005), 대한소화기학회
  4. Joo Young Eun, "A Case of Osteoclast-like Giant Cell Tumor of the Pancreas withDuctal Adenocarcinoma: Histopathological, Immunohistochemical,Ultrastructural and Molecular Biological Studies", Journal of Korean Medical Science, 20(3), pp.516~520 (2005), 대한의학회
  5. Sung SH, "Fine needle aspiration cytology of osteoclastic giant cell tumor of the pancreas", Korean J Cytopathol, 9, pp.89~94 (1998)
  6. Jalloh SS, "Giant cell tumour (osteoclastoma) of the pancreas: an epithelial tumour probably of pancreatic acinar origin", J Clin Pathol, 36, pp.1171~1175 (1983)
  7. Molberg KH, "Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas and periampullary region", Cancer, 82, pp.1279~1287 (1998)
  8. Sakai Y, "Origin of giant cells in osteoclast-like giant cell tumors of the pancreas", Hum Pathol, 31, pp.1223~1229 (2000)
  9. Layfield LJ, "Giant-cell containing neoplasms of the pancreas: an aspiration cytology study", Diagn Cytopathol, 36, pp.238~244 (2008)
  10. Nai GA, "Osteoclast-like giant cell tumor of the pancreas associated with mucus-secreting adenocarcinoma: case report and discussion of the histogenesis", Pancreatology, 5, pp.279~284 (2005)
  11. Tezuka K, "An unusual case of undifferentiated carcinoma in situ with osteoclast- like giant cells of the pancreas", Pancreas, 33, pp.304~310 (2006)
  12. Shiozawa M, "Osteoclast-like giant cell tumor of the pancreas", Int J Clin Oncol, 7, pp.376~380 (2002)
  13. Bauditz J, "Osteoclast-like giant cell tumors of the pancreas and liver", World J Gastroenterol, 12, pp.7878~7883 (2006)

관련 논문AI추천

이 간행물의 다른 논문 (11건)