Moxifloxacin에 의해 발생한 Stevens-Johnson 증후군 1예
A case of Stevens-Johnson syndrome caused by moxifloxacin
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초록
본 증례는 빠른 진단과 의심되는 약제의 투여 중단 및 합병증에 관심을 기울여 회복시켰던 moxifloxacin에 의해 병발된 것으로 추정된 스티븐 존슨 증후군으로, 국내에서 moxifloxacin 사용 후 스티븐 존슨 증후군이 발생한 예가 없어 문헌고찰과 함께 보고하는 바이다.
Abstract
Stevens-Johnson syndrome is an acute life-threatening disease. Antibiotics such as cephalosporins and quinolone are rarely associated with severe adverse skin reactions. We reported a case of Stevens-Johnson syndrome in a 62-year-old male thought to be caused by the use of moxifloxacin. After using moxifloxacin for a period of 2 weeks, the patient developed diffuse maculopapular eruptions over his entire body. The histological and clinical features were compatible with those of Stevens-Johnson syndrome. We concluded that, although uncommon, moxifloxacin can cause severe adverse skin reactions in some patients who are allergic to certain antibiotics. (Korean J Med 77:S1124-S1127, 2009)
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