폐와 간전이를 동반한 집합관 신세포암(Bellini관 암) 1예
Metastatic collecting duct (Bellini duct) carcinoma: A case report
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초록
집합관 신세포암은 드물지만 사망률이 높은 심각한 질환이다. 그러나 조직학적 분류로는 신세포암에 속하지만 발생학 및 조직학적으로 요로상피암과 비슷한 특징을 보여 신장암과 달리 요로상피암에 준하는 치료가 시도되고 있다. 본 증례에서 저자들은 M-VAC 병용항암요법에 반응을 보인 전이성 집합관 신세포암을 경험하였기에 문헌고찰과 함께 보고하는 바이다.
Abstract
Renal cell carcinoma accounts for 2.6% of all cancer, and most renal cell carcinoma has a clear cell origin. Bellini duct carcinoma, which arises from collecting duct cells (Bellini cells), is a rare type of renal cell carcinoma, constituting less than 1% of all renal cell carcinoma. The prognosis of Bellini duct carcinoma is very poor, and more than 60% of the patients die within 2 years of diagnosis. There is no consensus regarding the optimal treatment. We report a case of Bellini duct carcinoma in a 53-year-old male with multiple lung and liver metastases. The patient was treated with eight cycles of M-VAC (methotrexate, vincristine, doxorubicin, and cisplatin) combination chemotherapy. The patient currently shows a radiological partial response without disease progression 10 months after the chemotherapy.
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