The Mechanism of and Preventive Therapy for Stroke in Patients with Atrial Fibrillation
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초록
Atrial fibrillation is a major cardiac cause of stroke, and a pathogenesis involving thrombus formation in patients with atrial fibrillation is well established. A strategy for rhythm control that involves catheter ablation and anticoagulation therapy is evolving. A strategy for rhythm control that restores and maintains sinus rhythm should reduce the risk of ischemic stroke that is associated with atrial fibrillation; however, this is yet to be proven in large-scale randomized controlled trials. This paper reviews the emerging role of rhythm control therapy for atrial fibrillation to prevent stroke.
Abstract
Atrial fibrillation is a major cardiac cause of stroke, and a pathogenesis involving thrombus formation in patients with atrial fibrillation is well established. A strategy for rhythm control that involves catheter ablation and anticoagulation therapy is evolving. A strategy for rhythm control that restores and maintains sinus rhythm should reduce the risk of ischemic stroke that is associated with atrial fibrillation; however, this is yet to be proven in large-scale randomized controlled trials. This paper reviews the emerging role of rhythm control therapy for atrial fibrillation to prevent stroke.
참고문헌 (82)
- Chugh SS, "Worldwide epidemiology of atrial fibrillation : a Global Burden of Disease 2010 Study", Circulation, 129, pp.837~847 (2014)
- Phillips SJ, "Is atrial fibrillation an independent risk factor for stroke?", Can J Neurol Sci, 17, pp.163~168 (1990)
- Go AS, "Prevalence of diagnosed atrial fibrillation in adults : national implications for rhythm management and stroke prevention : the AnTicoagulation and Risk Factors in Atrial Fibrillation(ATRIA)Study", JAMA, 285, pp.2370~2375 (2001)
- Marini C, "Contribution of atrial fibrillation to incidence and outcome of ischemic stroke : results from a population-based study", Stroke, 36, pp.1115~1119 (2005)
- Sacco RL, "Infarcts of undetermined cause : the NINCDS Stroke Data Bank", Ann Neurol, 25, pp.382~390 (1989)
- Jauch EC, "Guidelines for the early management of patients with acute ischemic stroke : a guideline for healthcare professionals from the American Heart Association", American Stroke Association, 2013, pp.44, 870~947
- Kernan WN, "Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack : a guideline for healthcare professionals from the American Heart Association", American Stroke Association, 2014, pp.45, 2160~2236
- Dussault C, "Electrocardiographic monitoring for detecting atrial fibrillation after ischemic stroke or transient ischemic attack : systematic review and meta-analysis", Circ Arrhythm Electrophysiol, 8, pp.263~269 (2015)
- Poller L, "Dabigatran versus warfarin in patients with atrial fibrillation", N Engl J Med, 361, pp.2673~2674 (2009)
- Patel MR, "Rivaroxaban versus warfarin in nonvalvular atrial fibrillation", N Engl J Med, 365, pp.883~891 (2011)
- Granger CB, "Apixaban versus warfarin in patients with atrial fibrillation", N Engl J Med, 365, pp.981~992 (2011)
- Ostermayer SH, "Percutaneous left atrial appendage transcatheter occlusion(PLAATO system)to prevent stroke in high-risk patients with non-rheumatic atrial fibrillation : results from the international multi-center feasibility trials", J Am Coll Cardiol, 46, pp.9~14 (2005)
- Holmes DR, "Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation : a randomised non-inferiority trial", Lancet, 374, pp.534~542 (2009)
- Hagens VE, "Rate control versus rhythm control for patients with persistent atrial fibrillation with mild to moderate heart failure : results from the RAte Control versus Electrical cardioversion(RACE)study", Am Heart J, 149, pp.1106~1111 (2005)
- Corley SD, "Relationships between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study", Circulation, 109, pp.1509~1513 (2004)
- Andrade J, "The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms", Circ Res, 114, pp.1453~1468 (2014)
- Putaala J, "Prime time for dissecting the entity of cryptogenic stroke", Stroke, 45, pp.950~952 (2014)
- Gladstone DJ, "Atrial fibrillation in patients with cryptogenic stroke", N Engl J Med, 370, pp.2467~2477 (2014)
- Brambatti M, "Temporal relationship between subclinical atrial fibrillation and embolic events", Circulation, 129, pp.2094~2099 (2014)
- Martin DT, "Randomized trial of atrial arrhythmia monitoring to guide anticoagulation in patients with implanted defibrillator and cardiac resynchronization devices", Eur Heart J, 36, pp.1660~1668 (2015)
- Ip J, "Multicenter randomized study of anticoagulation guided by remote rhythm monitoring in patients with implantable cardioverter-defibrillator and CRT-D devices: rationale, design, and clinical characteristics of the initially enrolled cohort The IMPACT study", Am Heart J, 158, pp.364~370 (2009)
- Daccarett M, "Association of left atrial fibrosis detected by delayed-enhancement magnetic resonance imaging and the risk of stroke in patients with atrial fibrillation", J Am Coll Cardiol, 57, pp.831~838 (2011)
- Akoum N, "Association of atrial fibrosis quantified using LGE-MRI with atrial appendage thrombus and spontaneous contrast on transesophageal echocardiography in patients with atrial fibrillation", J Cardiovasc Electrophysiol, 24, pp.1104~1109 (2013)
- Pollick C, "Assessment of left atrial appendage function by transesophageal echocardiography. Implications for the development of thrombus", Circulation, 84, pp.223~231 (1991)
- Leung DY, "Prognostic implications of left atrial spontaneous echo contrast in nonvalvular atrial fibrillation", J Am Coll Cardiol, 24, pp.755~762 (1994)
- study), "J Am Soc Echocardiogr", 1999, 1088~1096
- Habibi M, "Association of left atrial function and left atrial enhancement in patients with atrial fibrillation: cardiac magnetic resonance study", Circ Cardiovasc Imaging, 8, pp.e002769~ (2015)
- Mahnkopf C, "Evaluation of the left atrial substrate in patients with lone atrial fibrillation using delayed-enhanced MRI : implications for disease progression and response to catheter ablation", Heart Rhythm, 7, pp.1475~1481 (2010)
- Akoum N, "Atrial fibrosis helps select the appropriate patient and strategy in catheter ablation of atrial fibrillation : a DE-MRI guided approach", J Cardiovasc Electrophysiol, 22, pp.16~22 (2011)
- Beinart R, "Cardiac magnetic resonance T1 mapping of left atrial myocardium", Heart Rhythm, 10, pp.1325~1331 (2013)
- Fluckiger JU, "Left atrial flow velocity distribution and flow coherence using four-dimensional FLOW MRI : a pilot study investigating the impact of age and Pre-and Postintervention atrial fibrillation on atrial hemodynamics", J Magn Reson Imaging, 38, pp.580~587 (2013)
- Yamamoto M, "Complex left atrial appendage morphology and left atrial appendage thrombus formation in patients with atrial fibrillation", Circ Cardiovasc Imaging, 7, pp.337~343 (2014)
- Fatkin D, "Relations between left atrial appendage blood flow velocity, spontaneous echocardiographic contrast and thromboembolic risk in vivo", J Am Coll Cardiol, 23, pp.961~969 (1994)
- Beinart R, "Left atrial appendage dimensions predict the risk of stroke", TIA in patients with atrial fibrillation, 2011, pp.22, 10~15
- Mügge A, "Assessment of left atrial appendage function by biplane transesophageal echocardiography in patients with nonrheumatic atrial fibrillation : identification of a subgroup of patients at increased embolic risk", J Am Coll Cardiol, 23, pp.599~607 (1994)
- Kishima H, "Masuyama T. Does Left Atrial Appendage Morphology Influence Left Atrial Appendage Flow Velocity?", Circ J, 79, pp.1706~1711 (2015)
- Fukushima K, "Correlation between left atrial appendage morphology and flow velocity in patients with paroxysmal atrial fibrillation", Eur Heart J Cardiovasc Imaging, 17, pp.59~66 (2016)
- Di Biase L, "Does the left atrial appendage morphology correlate with the risk of stroke in patients with atrial fibrillation? Results from a multicenter study", J Am Coll Cardiol, 60, pp.531~538 (2012)
- Nedios S, "Left atrial appendage morphology and thromboembolic risk after catheter ablation for atrial fibrillation", Heart Rhythm, 11, pp.2239~2246 (2014)
- Shin SY, "Improved endothelial function in patients with atrial fibrillation through maintenance of sinus rhythm by successful catheter ablation", J Cardiovasc Electrophysiol, 22, pp.376~382 (2011)
- Tousoulis D, "Oxidative stress and inflammatory process in patients with atrial fibrillation : the role of left atrium distension", Int J Cardiol, 136, pp.258~262 (2009)
- Makin AJ, "Assessment of endothelial damage in atherosclerotic vascular disease by quantification of circulating endothelial cells. Relationship with von Willebrand factor and tissue factor", Eur Heart J, 25, pp.371~376 (2004)
- Chung MK, "C-reactive protein elevation in patients with atrial arrhythmias : inflammatory mechanisms and persistence of atrial fibrillation", Circulation, 104, pp.2886~2891 (2001)
- Study), "Am J Cardiol", 2012, 95~99
- Lip GY, "Increased markers of thrombogenesis in chronic atrial fibrillation : effects of warfarin treatment", Br Heart J, 73, pp.527~533 (1995)
- Heppell RM, "Haemostatic and haemodynamic abnormalities associated with left atrial thrombosis in non-rheumatic atrial fibrillation", Heart, 77, pp.407~411 (1997)
- Lip GY, "Additive role of plasma von Willebrand factor levels to clinical factors for risk stratification of patients with atrial fibrillation", Stroke, 37, pp.2294~2300 (2006)
- Cooke JP, "Asymmetrical dimethylarginine: the Uber marker?", Circulation, 109, pp.1813~1818 (2004)
- Matsuoka H, "Asymmetrical dimethylarginine, an endogenous nitric oxide synthase inhibitor, in experimental hypertension", Hypertension, 29, pp.242~247 (1997)
- Abbasi F, "Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus", Am J Cardiol, 88, pp.1201~1203 (2001)
- Miyazaki H, "Endogenous nitric oxide synthase inhibitor : a novel marker of atherosclerosis", Circulation, 99, pp.1141~1146 (1999)
- Skanes AC, "Focused 2012 update of the Canadian Cardiovascular Society atrial fibrillation guidelines : recommendations for stroke prevention and rate", rhythm control, 2012, pp.28, 125~136
- Cowan C, "The use of anticoagulants in the management of atrial fibrillation among general practices in England", Heart, 99, pp.1166~1172 (2013)
- O’Brien EC, "Physician practices regarding contraindications to oral anticoagulation in atrial fibrillation : findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation(ORBIT-AF)registry", Am Heart J, 167, pp.601~609 (2014)
- Sacco RL, "An updated definition of stroke for the 21st century : a statement for healthcare professionals from the American Heart Association", American Stroke Association, 2013, pp.44, 2064~2089
- Brott T, "Baseline silent cerebral infarction in the Asymptomatic Carotid Atherosclerosis Study", Stroke, 25, pp.1122~1129 (1994)
- Hara M, "Silent cortical strokes associated with atrial fibrillation", Clin Cardiol, 18, pp.573~574 (1995)
- Cha MJ, "Prevalence of and risk factors for silent ischemic stroke in patients with atrial fibrillation as determined by brain magnetic resonance imaging", Am J Cardiol, 113, pp.655~661 (2014)
- Marfella R, "Brief episodes of silent atrial fibrillation predict clinical vascular brain disease in type 2 diabetic patients", J Am Coll Cardiol, 62, pp.525~530 (2013)
- Kalantarian S, "Cognitive impairment associated with atrial fibrillation : a meta-analysis", Ann Intern Med, 158, pp.338~346 (2013)
- Gaita F, "Prevalence of silent cerebral ischemia in paroxysmal and persistent atrial fibrillation and correlation with cognitive function", J Am Coll Cardiol, 62, pp.1990~1997 (2013)
- Roy D, "Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators", N Engl J Med, 342, pp.913~920 (2000)
- Bonanno C, "Efficacy and safety of catheter ablation versus antiarrhythmic drugs for atrial fibrillation : a meta-analysis of randomized trials", J Cardiovasc Med, 11, pp.408~418 (2010)
- Jais P, "Catheter ablation versus antiarrhythmic drugs for atrial fibrillation : the A4 study", Circulation, 118, pp.2498~2505 (2008)
- Pappone C, "A randomized trial of circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation : the APAF Study", J Am Coll Cardiol, 48, pp.2340~2347 (2006)
- Piccini JP, "Pulmonary vein isolation for the maintenance of sinus rhythm in patients with atrial fibrillation: a meta-analysis of randomized, controlled trials", Circ Arrhythm Electrophysiol, 2, pp.626~633 (2009)
- Bunch TJ, "Patients treated with catheter ablation for atrial fibrillation have long-term rates of death, stroke, and dementia similar to patients without atrial fibrillation", J Cardiovasc Electrophysiol, 22, pp.839~845 (2011)
- Reynolds MR, "Health outcomes with catheter ablation or antiarrhythmic drug therapy in atrial fibrillation : results of a propensity-matched analysis", Circ Cardiovasc Qual Outcomes, 5, pp.171~181 (2012)
- Chang CH, "Effect of radiofrequency catheter ablation for atrial fibrillation on morbidity and mortality : a nationwide cohort study and propensity score analysis", Circ Arrhythm Electrophysiol, 7, pp.76~82 (2014)
- Haissaguerre M, "Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins", N Engl J Med, 339, pp.659~666 (1998)
- Oral H, "Risk of thromboembolic events after percutaneous left atrial radiofrequency ablation of atrial fibrillation", Circulation, 114, pp.759~765 (2006)
- Nademanee K, "Clinical outcomes of catheter substrate ablation for high-risk patients with atrial fibrillation", J Am Coll Cardiol, 51, pp.843~849 (2008)
- Bunch TJ, "Warfarin is not needed in low-risk patients following atrial fibrillation ablation procedures", J Cardiovasc Electrophysiol, 20, pp.988~993 (2009)
- Themistoclakis S, "The risk of thromboembolism and need for oral anticoagulation after successful atrial fibrillation ablation", J Am Coll Cardiol, 55, pp.735~743 (2010)
- Saad EB, "Very low risk of thromboembolic events in patients undergoing successful catheter ablation of atrial fibrillation with a CHADS2 score ≤3 : a long-term outcome study", Circ Arrhythm Electrophysiol, 4, pp.615~621 (2011)
- Yagishita A, "Incidence of late thromboembolic events after catheter ablation of atrial fibrillation", Circ J, 75, pp.2343~2349 (2011)
- Guiot A, "Anticoagulant therapy and risk of cerebrovascular events after catheter ablation of atrial fibrillation in the elderly", J Cardiovasc Electrophysiol, 23, pp.36~43 (2012)
- Friberg L, "Catheter ablation for atrial fibrillation is associated with lower incidence of stroke and death: data from Swedish health registries", Eur Heart J (2016)[DOI]
- Bertaglia E, "Long term follow up of radiofrequency catheter ablation of atrial flutter : clinical course and predictors of atrial fibrillation occurrence", Heart, 90, pp.59~63 (2004)
- Medi C, "Pulmonary vein antral isolation for paroxysmal atrial fibrillation : results from long-term follow-up", J Cardiovasc Electrophysiol, 22, pp.137~141 (2011)
- Ouyang F, "Long-term results of catheter ablation in paroxysmal atrial fibrillation : lessons from a 5-year follow-up", Circulation, 122, pp.2368~2377 (2010)
- Wokhlu A, "Long-term outcome of atrial fibrillation ablation : impact and predictors of very late recurrence", J Cardiovasc Electrophysiol, 21, pp.1071~1078 (2010)
