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The Clinical and Metabolic Effects of Intragastric Balloon on Morbid Obesity and Its Related Comorbidities

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초록

Obesity is becoming increasingly prevalent worldwide, and its metabolic sequelae lead to a significant burden on healthcareresources. Options for the management of obesity include lifestyle modification, pharmacological treatment, surgery, and endoscopicbariatric therapies (EBTs). Among these, EBTs are more effective than diet and lifestyle modification and are less invasive thanbariatric surgery. In recent years, there have been significant advances in technologies pertaining to EBTs. Of all the available EBTs,there is a significant amount of clinical experience and published data regarding intragastric balloons (IGBs) because of theircomparatively long development period. Currently, the United States Food and Drug Administration (FDA) has approved threeIGBs, including Orbera (Apollo Endosurgery, Austin, TX, USA), ReShape Duo (ReShape Medical, San Clemente, CA, USA), andObalon (Obalon Therapeutics, Carlsbad, CA, USA). The aim of this review is to summarize the available literature on the efficacy ofIGBs in weight loss and their impact on obesity-related metabolic diseases.

Abstract

Obesity is becoming increasingly prevalent worldwide, and its metabolic sequelae lead to a significant burden on healthcareresources. Options for the management of obesity include lifestyle modification, pharmacological treatment, surgery, and endoscopicbariatric therapies (EBTs). Among these, EBTs are more effective than diet and lifestyle modification and are less invasive thanbariatric surgery. In recent years, there have been significant advances in technologies pertaining to EBTs. Of all the available EBTs,there is a significant amount of clinical experience and published data regarding intragastric balloons (IGBs) because of theircomparatively long development period. Currently, the United States Food and Drug Administration (FDA) has approved threeIGBs, including Orbera (Apollo Endosurgery, Austin, TX, USA), ReShape Duo (ReShape Medical, San Clemente, CA, USA), andObalon (Obalon Therapeutics, Carlsbad, CA, USA). The aim of this review is to summarize the available literature on the efficacy ofIGBs in weight loss and their impact on obesity-related metabolic diseases.

참고문헌 (72)

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