Contrast Harmonic Endoscopic Ultrasound in Pancreatic Diseases
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Endoscopic ultrasound (EUS) was first described in 1986, with the aim of overcoming the problems affecting transabdominalultrasound imaging, mainly problems related to the interposition of gas, and artifacts produced by bone or fat. Now, EUS can beconsidered as the best method for the analysis of pancreatic diseases, overtaking the diagnostic accuracy of computed tomographyand magnetic resonance imaging. However, fundamental B-mode imaging is limited for the diagnosis of solid pancreatic lesions,because most of them are depicted as heterogeneous and hypo-echoic, and it is difficult to differentiate between benign andmalignant lesions. Similar to how perfusion patterns obtained by computed tomography or magnetic resonance imaging afterinjection of contrast agents allow for the characterization of focal lesions, EUS has also recently been introduced to the use of contrastagents for performing contrast-enhanced harmonic EUS (CEH-EUS), which has the capability to distinguish the type of perfusionbetween lesions and surrounding tissue. CEH-EUS has shown its usefulness for the diagnosis and characterization of solid pancreaticlesions. Moreover, CEH-EUS is also highly accurate for distinguishing non-neoplastic from neoplastic cysts in pancreatic lesions. Another potential role of CEH-EUS is its ability to direct EUS-guided tissue acquisition.
Abstract
Endoscopic ultrasound (EUS) was first described in 1986, with the aim of overcoming the problems affecting transabdominalultrasound imaging, mainly problems related to the interposition of gas, and artifacts produced by bone or fat. Now, EUS can beconsidered as the best method for the analysis of pancreatic diseases, overtaking the diagnostic accuracy of computed tomographyand magnetic resonance imaging. However, fundamental B-mode imaging is limited for the diagnosis of solid pancreatic lesions,because most of them are depicted as heterogeneous and hypo-echoic, and it is difficult to differentiate between benign andmalignant lesions. Similar to how perfusion patterns obtained by computed tomography or magnetic resonance imaging afterinjection of contrast agents allow for the characterization of focal lesions, EUS has also recently been introduced to the use of contrastagents for performing contrast-enhanced harmonic EUS (CEH-EUS), which has the capability to distinguish the type of perfusionbetween lesions and surrounding tissue. CEH-EUS has shown its usefulness for the diagnosis and characterization of solid pancreaticlesions. Moreover, CEH-EUS is also highly accurate for distinguishing non-neoplastic from neoplastic cysts in pancreatic lesions. Another potential role of CEH-EUS is its ability to direct EUS-guided tissue acquisition.
참고문헌 (10)
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