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납 함유 한약환에 의한 철적모구빈혈(sideroblastic anemia) 1예

A case of sideroblastic anemia caused by lead-containing herbal medication

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키워드

주제분류내과학

초록

납중독은 이차성 철적모구성빈혈의 원인으로 알려져 있으며, 아시아에서는 한약 복용이 납중독의 중요한 원인으로 여겨지고 있다. 그러나 국내에서는 한약으로 인한 이차성 철적모구성빈혈의 발표가 없었다. 저자는 복통과 빈혈을 주소로 내원한 34세 여자 환자에 대해 혈청 납농도 및 복용하였던 한약의 납함량 조사를 통해 이차성 철적모구성빈혈을 진단하였고, 한약 복용 중지 후 특별한 치료없이 범혈구 감소가 서서히 회복된 증례를 경험하였기에 이를 보고한다.

Abstract

Although lead intoxication is commonly mentioned as a cause of sideroblastic anemia, no well‐documented case exists in the literature. We encountered a patient with sideroblastic anemia caused by lead‐containing herbal medicine. A 34‐year‐old woman was admitted to our hospital with abdominal pain. She had taken herbal medicine for her general health. Anemia, hyperbilirubinemia, and elevated lactic dehydrogenase were found from the laboratory data. Bone marrow biopsy showed pathological ringed sideroblasts. Her serum level of lead was high and the lead content of the tablet was higher than permitted. We diagnosed her with sideroblastic anemia secondary to lead poisoning caused by herbal medicine. We stopped her from taking herbal medicine and she gradually recovered from anemia.

참고문헌 (11)

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  9. 김지연, "최근 30년간 국내 논문에 보고된 납중독증에 대한 고찰", 대한내과학회지, 66(6), pp.617~624 (2004), 대한내과학회
  10. Oh SW, "The study on heavy metal contamination of traditional drugs (Herbpills)", Research Laboratory, Korean Medical Association, 6~40 (1983)
  11. Fischbein A, "Occupational and environmental exposure to lead. In: Environmental and occupational medicine. 4th ed", pp.2007, Wolters Kluwer

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