본문 바로가기
KERD
논문KCI 등재

보존적 치료로 호전된 시력소실을 동반한 급성 A형 간염 1예

Conservative Care was Successfully Used to Manage Acute Hepatitis A Infection with Blindness

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류내과학

초록

저자 등은 시력저하를 동반한 급성 대사성 뇌병증이 급성A형 간염과 동반하여 발생할 수 있음을 확인하였고, 급성 A 형 간염 환자에서 적극적인 보존적 요법으로 시력소실 등의신경학적 증상에 대해 능동적인 대처를 권고하며 국내에서보고된 바가 없기에 문헌고찰과 함께 보고하는 바이다.

Abstract

Hepatitis A is usually a mild, self-limiting illness, but in certain cases it can develop into a severe or fatal disease. The most common symptoms of acute hepatitis A virus (HAV) infection are fever, myalgia, nausea, vomiting, jaundice, and abdominal pain. Extrahepatic symptoms are rare, especially neurologic manifestations. We investigated a 34-year-old male who presented after suffering two days of fever, chills and general myalgia. His condition gradually deteriorated and he developed sudden blindness on day nine. This blindness lasted for 20 min and at this point abnormal brain images were observed. Initial tests for immunoglobulin M anti HAV were negative. These tests were repeated, later confirming acute HAV infection. After conservative management, the individual fully recovered. We report this extremely rare acute HAV infection case with metabolic encephalopathy exhibiting transient blindness. (Korean J Med 2011;80:S305-S309)

참고문헌 (19)

  1. Shapiro CN, "Worldwide epidemiology of hepatitis A virus infection", J Hepatol, 18(Suppl 2), pp.S11~S14 (1993)
  2. Cuthbert JA, "Hepatitis A: old and new", Clin Microbiol Rev, 14, pp.38~58 (2001)
  3. 이응준, "최근 2년간 발생한 급성 A형간염의 임상 특성에 관한 연구", 대한소화기학회지, 52(5), pp.298~303 (2008), 대한소화기학회
  4. 이안나, "최근 4년 동안 전국의료기관에서 의뢰된 A형 간염바이러스 혈청 표지자 검사 결과에 대한 역학 분석", Annals of Laboratory Medicine, 29(6), pp.563~569 (2009), 대한진단검사의학회
  5. Jung YK, "Epidemiology and clinical features of acute hepatitis A: from the domestic perspective", Korean J Hepatol, 15, pp.438~445 (2009)
  6. 석효선, "비전격성 급성 A형 간염에 합병된 급성 신부전증의 1예", 대한내과학회지, 74(5), pp.551~555 (2008), 대한내과학회
  7. Lee SM, "A case of acute renal failure and IgA nephropathy associated with acute hepatitis A", Korean J Med, 67(Suppl 3), pp.S804~S808 (2004)
  8. Cho HJ, "A case of acute pancreatitis in acute hepatitis A infection", Korean J Gastroenterol, 39, pp.437~440 (2002)
  9. 김동일, "A형 간염에 동반된 흉막 삼출 1예", Pediatric Gastroenterology, Hepatology & Nutrition, 8(2), pp.243~246 (2005), 대한소아소화기영양학회
  10. Hammond GW, "Encephalitis during the prodromal stage of acute hepatitis A", Can Med Assoc J, 126, pp.269~270 (1982)
  11. Kim HI, "A case of acute viral encephalitis in acute hepatitis A infection", Korean J Med, 77, pp.S255~S257 (2009)
  12. Breningstall GN, "Acute transverse myelitis and brainstem encephalitis associated with hepatitis A infection", Pediatr Neurol, 12, pp.169~171 (1995)
  13. Lee DK, "Guillain-Barre like syndrome associated with acute renal failure and thrombocytopenia following acute viral hepatitis A", Korean Med Sci, 12, pp.151~156 (1997)
  14. Hinchey J, "A reversible posterior leukoencephalopathy syndrome", N Engl J Med, 334, pp.494~500 (1996)
  15. Bartynski WS, "Posterior reversible encephalopathy syndrome, part 1: fundamental imaging and clinical features", AJNR Am J Neuroradiol, 29, pp.1036~1042 (2008)
  16. Bartynski WS, "Posterior reversible encephalopathy syndrome in infection, sepsis, and shock", AJNR Am J Neuroradiol, 27, pp.2179~2190 (2006)
  17. Steininger C, "Acute encephalopathy associated with influenza A virus infection", Clin Infect Dis, 36, pp.567~574 (2003)
  18. Hughes PJ, "Probable post-hepatitis A vaccination encephalopathy", Lancet, 342, pp.302~ (1993)
  19. Rogalewski A, "Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis", Neuropsychiatr Dis Treat, 3, pp.987~991 (2007)

관련 논문AI추천

이 간행물의 다른 논문 (39건)