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Capsule enteroscopy versus small-bowel ultrasonography for the detection and differential diagnosis of intestinal diseases

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Background/Aims: Capsule enteroscopy (CE) and intestinal ultrasonography (IUS) are techniques that are currently used for investigatingsmall-bowel (SB) diseases. The aim of this study was to compare the main imaging findings and the lesion detection rate (LDR)of CE and IUS in different clinical scenarios involving the SB. Methods: We retrospectively enrolled patients who underwent CE and IUS for obscure gastrointestinal bleeding (OGIB), complicatedceliac disease (CeD), and suspected or known inflammatory bowel disease (IBD). We evaluated the LDR of both techniques. The accuracyof IUS was determined using CE as the reference standard. Results: A total of 159 patients (113 female; mean age, 49±19 years) were enrolled. The LDR was 55% and 33% for CE and IUS(p<0.05), respectively. Subgroup analysis showed that the LDR of CE was significantly higher than that of IUS in patients with OGIB(62% vs. 14%, p<0.05) and CeD (55% vs. 35%, p<0.05). IUS showed a similar LDR to CE in patients with suspected or known IBD (51%vs. 46%, p=0.83). Conclusions: CE should be preferred in cases of OGIB and CeD, whereas IUS should be considered an early step in the diagnosis andfollow-up of IBD even in patients with a proximal SB localization of the disease.

Abstract

Background/Aims: Capsule enteroscopy (CE) and intestinal ultrasonography (IUS) are techniques that are currently used for investigatingsmall-bowel (SB) diseases. The aim of this study was to compare the main imaging findings and the lesion detection rate (LDR)of CE and IUS in different clinical scenarios involving the SB. Methods: We retrospectively enrolled patients who underwent CE and IUS for obscure gastrointestinal bleeding (OGIB), complicatedceliac disease (CeD), and suspected or known inflammatory bowel disease (IBD). We evaluated the LDR of both techniques. The accuracyof IUS was determined using CE as the reference standard. Results: A total of 159 patients (113 female; mean age, 49±19 years) were enrolled. The LDR was 55% and 33% for CE and IUS(p<0.05), respectively. Subgroup analysis showed that the LDR of CE was significantly higher than that of IUS in patients with OGIB(62% vs. 14%, p<0.05) and CeD (55% vs. 35%, p<0.05). IUS showed a similar LDR to CE in patients with suspected or known IBD (51%vs. 46%, p=0.83). Conclusions: CE should be preferred in cases of OGIB and CeD, whereas IUS should be considered an early step in the diagnosis andfollow-up of IBD even in patients with a proximal SB localization of the disease.

참고문헌 (20)

  1. Monkemuller K, "Should we illuminate the black box of the small bowel mucosa from above or below?", Clin Gastroenterol Hepatol, 10, pp.917~919 (2012)
  2. Eliakim R, "Endoscopic assessment of the small bowel", Dig Dis, 31, pp.194~198 (2013)
  3. Fidler JL, "Small bowel imaging : computed tomography enterography, magnetic resonance enterography, angiography, and nuclear medicine", Gastrointest Endosc Clin N Am, 27, pp.133~152 (2017)
  4. Pennazio M, "Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders : European Society of Gastrointestinal Endoscopy(ESGE)Clinical Guideline", Endoscopy, 47, pp.352~376 (2015)
  5. Maconi G, "Ultrasound of the gastrointestinal tract" (2014), Springer
  6. Wale A, "Current role of ultrasound in small bowel imaging", Semin Ultrasound CT MR, 37, pp.301~312 (2016)
  7. Parente F, "Bowel ultrasound in assessment of Crohn’s disease and detection of related small bowel strictures : a prospective comparative study versus x ray and intraoperative findings", Gut, 50, pp.490~495 (2002)
  8. Fraquelli M, "Role of US in detection of Crohn disease : meta-analysis", Radiology, 236, pp.95~101 (2005)
  9. Nylund K, "Gastrointestinal wall thickness measured with transabdominal ultrasonography and its relationship to demographic factors in healthy subjects", Ultraschall Med, 33, pp.E225~E232 (2012)
  10. Nylund K, "EFSUMB recommendations and guidelines for gastrointestinal ultrasound : part 1 : examination techniques and normal findings(long version)", Ultraschall Med, 38, pp.e1~e15 (2017)
  11. Fraquelli M, "Impact of intestinal ultrasound on the management of patients with inflammatory bowel disease : how to apply scientific evidence to clinical practice", Dig Liver Dis, 52, pp.9~18 (2020)
  12. Nylund K, "Sonography of the small intestine", World J Gastroenterol, 15, pp.1319~1330 (2009)
  13. Fraquelli M, "Accuracy of ultrasonography in predicting celiac disease", Arch Intern Med, 164, pp.169~174 (2004)
  14. Branchi F, "Enteroscopy and radiology for the management of celiac disease complications : time for a pragmatic roadmap", Dig Liver Dis, 48, pp.578~586 (2016)
  15. Marmo R, "Meta-analysis: capsule enteroscopy vs. conventional modalities in diagnosis of small bowel diseases", Aliment Pharmacol Ther, 22, pp.595~604 (2005)
  16. Aloi M, "Magnetic resonance enterography, small-intestine contrast US, and capsule endoscopy to evaluate the small bowel in pediatric Crohn’s disease : a prospective, blinded, comparison study", Gastrointest Endosc, 81, pp.420~427 (2015)
  17. Kopylov U, "Diagnostic yield of capsule endoscopy versus magnetic resonance enterography and small bowel contrast ultrasound in the evaluation of small bowel Crohn’s disease : systematic review and meta-analysis", Dig Liver Dis, 49, pp.854~863 (2017)
  18. Carter D, "The accuracy of intestinal ultrasound compared with small bowel capsule endoscopy in assessment of suspected Crohn’s disease in patients with negative ileocolonoscopy", Therap Adv Gastroenterol, 11, pp.1756284818765908~ (2018)
  19. Orlando S, "Ultrasound elasticity imaging predicts therapeutic outcomes of patients with Crohn’s disease treated with anti-tumour necrosis factor antibodies", J Crohns Colitis, 12, pp.63~70 (2018)
  20. Rezapour M, "Retention associated with video capsule endoscopy : systematic review and meta-analysis", Gastrointest Endosc, 85, pp.1157~1168 (2017)

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