갑상선 결절의 석회화와 갑상선 암
Calcification in Thyroid Nodule and Thyroid Cancer
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초록
종합하면, 석회화의 양상과 무관하게 석회화 유무만으로 본다면 전체적으로 악성 결절의 경우 양성인 경우에 비해 석회화를 동반하는 경우가 2배 정도 흔하다. 악성 결절에서 석회화를 동반한 경우 석회화의 양상별로 나누면 거대 석회화는 미세 석회화보다 2배 정도 흔하다. 양성 결절에서는 거대 석회화가 미세 석회화보다 10배 정도 흔하다. 이러한 점을 염두에 두고 결절의 초음파 소견을 해석하면 임상적 판단을 하는 데 도움이 될 것이다.
Abstract
Calcifications of thyroid nodules are often found in sonography reports and can be detected in both benign and malignant nodules. Although it is well known that micro-calcifications are associated with thyroid malignancy, especially in papillary thyroid carcinomas, the results for macro-calcifications are controversial. Yoon et al. evaluated the role of presence of macro-calcification in thyroid nodules for predicting malignancy by retrospectively analyzing FNAC data and sonographic findings in one institution, and showed that macro-calcification is also significantly associated with thyroid malignancy. Coarse calcifications were more commonly found in malignant nodules than in benign nodules, however, rim calcification was not associated with malignancy. We should carefully evaluate thyroid nodule(s) with calcification regardless of the pattern of calcification, and it would be mandatory to evaluate the clinical significance of rim calcification by prospective analysis. (Korean J Med 2012;83:319-321)
참고문헌 (9)
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