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Endoscopic activity in inflammatory bowel disease: clinical significance and application in practice

Kyeong Ok Kim
대한소화기내시경학회 (The Korean Society Of Gastrointestinal Endoscopy)|2022.07|Clinical Endoscopy|제55권 제4호|pp. 480-488|DOI 10.5946/ce.2022.108

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키워드

Inflammatory bowel diseasesEndoscopyMucosal healingDisease activity
주제분류내과학

초록

Endoscopy is vital for diagnosis, assessing treatment response, monitoring and surveillance in patients with inflammatory bowel disease(IBD). With the growing importance of mucosal healing as a treatment target, the assessment of disease activity by endoscopy hasbeen accepted as the standard of care for IBD. There are many endoscopic activity indices for facilitating standardized reporting of thegastrointestinal mucosal appearance in IBD, and each index has its strengths and weaknesses. Although most endoscopic indices donot have a clear-cut validated definition, endoscopic remission or mucosal healing is associated with favorable outcomes, such as a decreasedrisk of relapse. Therefore, experts suggest utilizing endoscopic indices for monitoring disease activity and optimizing treatmentto achieve remission. However, the regular monitoring of endoscopic activity is limited in practice owing to several factors, such as thecomplexity of the procedure, time consumption, inter-observer variability, and lack of a clear-cut, validated definition of endoscopicresponse or remission. Although experts have recently suggested consensus-based definitions, further studies are needed to define thevalues that can predict long-term outcomes.

Abstract

Endoscopy is vital for diagnosis, assessing treatment response, monitoring and surveillance in patients with inflammatory bowel disease(IBD). With the growing importance of mucosal healing as a treatment target, the assessment of disease activity by endoscopy hasbeen accepted as the standard of care for IBD. There are many endoscopic activity indices for facilitating standardized reporting of thegastrointestinal mucosal appearance in IBD, and each index has its strengths and weaknesses. Although most endoscopic indices donot have a clear-cut validated definition, endoscopic remission or mucosal healing is associated with favorable outcomes, such as a decreasedrisk of relapse. Therefore, experts suggest utilizing endoscopic indices for monitoring disease activity and optimizing treatmentto achieve remission. However, the regular monitoring of endoscopic activity is limited in practice owing to several factors, such as thecomplexity of the procedure, time consumption, inter-observer variability, and lack of a clear-cut, validated definition of endoscopicresponse or remission. Although experts have recently suggested consensus-based definitions, further studies are needed to define thevalues that can predict long-term outcomes.

참고문헌 (57)

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관련 논문AI추천

Chronological Review of Endoscopic Indices in Inflammatory Bowel Disease김은수, Joon Seop Lee, Won Moon대한소화기내시경학회 · Clinical Endoscopy2019 · 제52권 제2호Role of Advanced Endoscopic Imaging Techniques in the Management of Inflammatory Bowel Disease김은수대한소화기내시경학회 · Clinical Endoscopy2017 · 제50권 제5호Advances in the Endoscopic Assessment of Inflammatory Bowel Diseases: Cooperation between Endoscopic and Pathologic Evaluations천재희대한병리학회 · Journal of Pathology and Translational Medicine2015 · 제49권 제3호Clinical Significance of Residual Nonrectal Inflammation in Ulcerative Colitis Patients in Clinical Remission김영호, Chang Dong Kyung, Hong Sung Noh, Kim Eun Ran, Kim Tae Jun, Kong Sung Min, Shin Jongbeom거트앤리버 소화기연관학회협의회 · Gut and Liver2021 · 제15권 제3호De-escalation of Therapy in Patients with Quiescent Inflammatory Bowel DiseaseKobayashi Taku, Miyatani Yusuke거트앤리버 소화기연관학회협의회 · Gut and Liver2023 · 제17권 제2호Changing treatment paradigms for the management of inflammatory bowel diseaseByong Duk Ye, Jong Pil Im, Joo Sung Kim, You Sun Kim대한내과학회 · The Korean Journal of Internal Medicine2018 · 제33권 제1호

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