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Prevalence of Intracranial Aneurysm in Patients with Aortopathy: A Systematic Review with Meta-Analyses

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Background and Purpose Patients with aortic disease might have an increased risk of intracranial aneurysm (IA). We conducted this research to assess the prevalence of IA in patients with aortopathy, considering the impact of gender, age, and cardiovascular risk factors. Methods We searched PubMed and Scopus from inception to August 2019 for epidemiological studies reporting the prevalence of IA in patients with aortopathy. Random-effect meta-analyses were performed to calculate the overall prevalence, and the effect of risk factors on the prevalence was also evaluated. Anatomical location of IAs in patients suffered from distinct aortic disease was extracted and further analyzed. Results Thirteen cross-sectional studies involving 4,041 participants were included in this systematic review. We reported an estimated prevalence of 12% (95% confidence interval [CI], 9% to 14%) of IA in patients with aortopathy. The pooled prevalence of IA in patients with bicuspid aortic valve, coarctation of the aorta, aortic aneurysm, and aortic dissection was 8% (95% CI, 6% to 10%), 10% (95% CI, 7% to 14%), 12% (95% CI, 9% to 15%), and 23% (95% CI, 12% to 34%), respectively. Gender (female) and smoking are risk factors related to an increased risk of IA. The anatomical distribution of IAs was heterogeneously between participants with different aortic disease. Conclusions According to current epidemiological evidence, the prevalence of IA in patients with aortic disease is quadrupled compared to that in the general population, which suggests that an early IA screening should be considered among patients with aortic disease for timely diagnosis and treatment of IA.

Abstract

Background and Purpose Patients with aortic disease might have an increased risk of intracranial aneurysm (IA). We conducted this research to assess the prevalence of IA in patients with aortopathy, considering the impact of gender, age, and cardiovascular risk factors. Methods We searched PubMed and Scopus from inception to August 2019 for epidemiological studies reporting the prevalence of IA in patients with aortopathy. Random-effect meta-analyses were performed to calculate the overall prevalence, and the effect of risk factors on the prevalence was also evaluated. Anatomical location of IAs in patients suffered from distinct aortic disease was extracted and further analyzed. Results Thirteen cross-sectional studies involving 4,041 participants were included in this systematic review. We reported an estimated prevalence of 12% (95% confidence interval [CI], 9% to 14%) of IA in patients with aortopathy. The pooled prevalence of IA in patients with bicuspid aortic valve, coarctation of the aorta, aortic aneurysm, and aortic dissection was 8% (95% CI, 6% to 10%), 10% (95% CI, 7% to 14%), 12% (95% CI, 9% to 15%), and 23% (95% CI, 12% to 34%), respectively. Gender (female) and smoking are risk factors related to an increased risk of IA. The anatomical distribution of IAs was heterogeneously between participants with different aortic disease. Conclusions According to current epidemiological evidence, the prevalence of IA in patients with aortic disease is quadrupled compared to that in the general population, which suggests that an early IA screening should be considered among patients with aortic disease for timely diagnosis and treatment of IA.

참고문헌 (45)

  1. Vlak MH, "Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis", Lancet Neurol, 10, pp.626~636 (2011)
  2. Algra AM, "Procedural clinical complications, case-fatality risks, and risk factors in endovascular and neurosurgical treatment of unruptured intracranial aneurysms:a systematic review and meta-analysis", JAMA Neurol, 76, pp.282~293 (2019)
  3. Jung WS, "Prevalence of intracranial aneurysms in patients with aortic dissection", AJNR Am J Neuroradiol, 38, pp.2089~2093 (2017)
  4. Thompson BG, "Guidelines for the management of patients with unruptured intracranial aneurysms : a guideline for healthcare professionals from the American Heart Association", American Stroke Association, 2015, pp.46, 2368~2400
  5. Kuzmik GA, "Concurrent intracranial and thoracic aortic aneurysms", Am J Cardiol, 105, pp.417~420 (2010)
  6. Lee D, "High prevalence of intracranial aneurysms in patients with aortic dissection or aneurysm : feasibility of extended aorta CT angiography with involvement of intracranial arteries", J Neurointerv Surg, 9, pp.1017~1021 (2017)
  7. Rouchaud A, "Prevalence of intracranial aneurysms in patients with aortic aneurysms", AJNR Am J Neuroradiol, 37, pp.1664~1668 (2016)
  8. Shin YW, "Sitespecific relationship between intracranial aneurysm and aortic aneurysm", Stroke, 46, pp.1993~1996 (2015)
  9. Cook SC, "Assessment of the cerebral circulation in adults with coarctation of the aorta", Congenit Heart Dis, 8, pp.289~295 (2013)
  10. Schievink WI, "Screening for intracranial aneurysms in patients with bicuspid aortic valve", Neurology, 74, pp.1430~1433 (2010)
  11. Connolly HM, "Intracranial aneurysms in patients with coarctation of the aorta : a prospective magnetic resonance angiographic study of 100 patients", Mayo Clin Proc, 78, pp.1491~1499 (2003)
  12. Curtis SL, "Results of screening for intracranial aneurysms in patients with coarctation of the aorta", AJNR Am J Neuroradiol, 33, pp.1182~1186 (2012)
  13. Egbe AC, "Prevalence and predictors of intracranial aneurysms in patients with bicuspid aortic valve", Heart, 103, pp.1508~1514 (2017)
  14. Moher D, "Preferred reporting items for systematic reviews and meta-analyses : the PRISMA statement", PLoS Med, 6, pp.e1000097~ (2009)
  15. Fralick M, "Association of concussion with the risk of suicide : a systematic review and meta-analysis", JAMA Neurol, 76, pp.144~151 (2019)
  16. Søvik S, "Acute kidney injury in trauma patients admitted to the ICU : a systematic review and meta-analysis", Intensive Care Med, 45, pp.407~419 (2019)
  17. Donti A, "Frequency of intracranial aneurysms determined by magnetic resonance angiography in children(mean age 16)having operative or endovascular treatment of coarctation of the aorta(mean age 3)", Am J Cardiol, 116, pp.630~633 (2015)
  18. Wang JC, "Association between surgical repair of aortic aneurysms and the diagnosis of intracranial aneurysms", J Vasc Surg, 71, pp.481~489 (2020)
  19. Goyal MS, "Bicuspid aortic valves and thoracic aortic aneurysms in patients with intracranial aneurysms", Neurology, 84, pp.46~49 (2015)
  20. Miyazawa N, "Risk factors for the association of intracranial and aortic aneurysms", Acta Neurochir(Wien), 149, pp.221~229 (2007)
  21. Laukka D, "Prevalence of thoracic aortic aneurysms and dilatations in patients with intracranial aneurysms", J Vasc Surg, 70, pp.1801~1808 (2019)
  22. Kappetein AP, "The neural crest as a possible pathogenetic factor in coarctation of the aorta and bicuspid aortic valve", J Thorac Cardiovasc Surg, 102, pp.830~836 (1991)
  23. Kirby ML, "Neural crest cells contribute to normal aorticopulmonary septation", Science, 220, pp.1059~1061 (1983)
  24. Le Douarin NM, "The avian embryo as a model to study the development of the neural crest : a long and still ongoing story", Mech Dev, 121, pp.1089~1102 (2004)
  25. Rosenquist TH, "Impaired elastic matrix development in the great arteries after ablation of the cardiac neural crest", Anat Rec, 226, pp.347~359 (1990)
  26. Baas AF, "The intracranial aneurysm susceptibility genes HSPG2 and CSPG2 are not associated with abdominal aortic aneurysm", Angiology, 61, pp.238~242 (2010)
  27. Helgadottir A, "The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm", Nat Genet, 40, pp.217~224 (2008)
  28. Jelsig AM, "Novel ELN mutation in a family with supravalvular aortic stenosis and intracranial aneurysm", Eur J Med Genet, 60, pp.110~113 (2017)
  29. Luukkonen TM, "A balanced translocation truncates Neurotrimin in a family with intracranial and thoracic aortic aneurysm", J Med Genet, 49, pp.621~629 (2012)
  30. Regalado E, "Autosomal dominant inheritance of a predisposition to thoracic aortic aneurysms and dissections and intracranial saccular aneurysms", Am J Med Genet A, 155A, pp.2125~2130 (2011)
  31. Regalado ES, "Exome sequencing identifies SMAD3mutations as a cause of familial thoracic aortic aneurysm and dissection with intracranial and other arterial aneurysms", Circ Res, 109, pp.680~686 (2011)
  32. Ruigrok YM, "A comparison of genetic chromosomal loci for intracranial, thoracic aortic, and abdominal aortic aneurysms in search of common genetic risk factors", Cardiovasc Pathol, 17, pp.40~47 (2008)
  33. van ‘t Hof FN, "Shared genetic risk factors of intracranial, abdominal, and thoracic aneurysms", J Am Heart Assoc, 5, pp.e002603~ (2016)
  34. Worrall BB, "Genome screen to detect linkage to common susceptibility genes for intracranial and aortic aneurysms", Stroke, 40, pp.71~76 (2009)
  35. Norman PE, "Site specificity of aneurysmal disease", Circulation, 121, pp.560~568 (2010)
  36. Chen H, "Atlas of Genetic Diagnosis and Counseling", pp.1295~1300 (2012), Springer US
  37. Kim ST, "Neurovascular manifestations of connective-tissue diseases : a review", Interv Neuroradiol, 22, pp.624~637 (2016)
  38. Jung KH, "New pathophysiological considerations on cerebral aneurysms", Neurointervention, 13, pp.73~83 (2018)
  39. Kobeissi E, "Blood pressure, hypertension and the risk of abdominal aortic aneurysms: a systematic review and meta-analysis of cohort studies", Eur J Epidemiol, 34, pp.547~555 (2019)
  40. Erbel R, "2014 ESC guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC)", Eur Heart J, 35, pp.2873~2926 (2014)
  41. van ‘t Hof FN, "Genetic risk load according to the site of intracranial aneurysms", Neurology, 83, pp.34~39 (2014)
  42. Gould RA, "ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm", Nat Genet, 51, pp.42~50 (2019)
  43. Bjornsson T, "A rare missense mutation in MYH6 associates with non-syndromic coarctation of the aorta", Eur Heart J, 39, pp.3243~3249 (2018)
  44. Pinard A, "Genetics of thoracic and abdominal aortic diseases", Circ Res, 124, pp.588~606 (2019)
  45. Renard M, "Clinical validity of genes for heritable thoracic aortic aneurysm and dissection", J Am Coll Cardiol, 72, pp.605~615 (2018)

관련 논문AI추천

Letter to the Editor Regarding “Prevalence of Intracranial Aneurysm in Patients with Aortopathy: A Systematic Review with Meta-Analyses”Ajay Malhotra, Mihir Khunte, Xiao Wu대한뇌졸중학회 · 대한뇌졸중영문학회지2020 · 제22권 제3호Prevalence and Characteristics of Unruptured Cerebral Aneurysms in Ischemic Stroke PatientsJi Hwa Kim, Joonho Chung, Kyung Yul Lee, Sang Hyun Suh, Sung Jun Ahn, Yeo-Jin Oh대한뇌졸중학회 · 대한뇌졸중영문학회지2016 · 제18권 제3호Polymorphisms of Inflammatory Cytokine Genes and Risk for Intracranial Aneurysm: A Systematic Review and Meta-AnalysisBingyang Li, Junxia Yan, Liming Hu, Xin Liao연세대학교의과대학 · Yonsei Medical Journal2020 · 제61권 제5호Association Between Vertebral Arterial Tortuosity and Aneurysm Growth in Intracranial Vertebral Artery DissectionBum Joon Kim, Dong-Wha Kang, Jae Young Park, Jun Young Chang, Sang Hee Ha, Soo Jeong, Sun U. Kwon대한신경과학회 · Journal of Clinical Neurology2024 · 제20권 제6호Serum Cadmium Level Is Positively Associated with Unruptured Intracranial Aneurysm Incidence진가헌, Bich Nae Ri Yoon, Jun Beom Lee, Won Yong Kim대한가정의학회 · Korean Journal of Family Medicine2019 · 제40권 제4호Clinical Risk Factors Affecting Procedure-Related Major Neurological Complications in Unruptured Intracranial Aneurysms김용배, 서상현, 장이욱, 정준호, 주진양, 홍창기연세대학교의과대학 · Yonsei Medical Journal2015 · 제56권 제4호

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