피부근염에서 발생한 국소분절사구체경화증 환자 1예
A Case of Dermatomyositis with Focal Segmental Glomerulosclerosis
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초록
피부근염에서 신장병변이 나타나는 경우는 주로 횡문근융해로 인한 세뇨관 문제이며 드물게 사구체신염이 나타날수 있다. 저자들은 국내에 보고된 바 없는 피부근염에 동반된 국소분절사구체경화증을 경험하였기에 문헌고찰과 함께보고하는 바이다.
Abstract
A 59-year-old man visited our hospital for facial edema and muscle weakness in both lower extremities. He was diagnosed with dermatomyositis (DM) about 1 year previously, and sudden development of proteinuria was noted. Renal biopsy revealed focal global and segmental glomerulosclerosis with slight mesangial expansion. Glomerulonephritis is rare in DM. According to our review of related literature, membranous nephropathy is the main type of DM, while mesangial proliferative glomerulonephritis is the most common type in polymyositis. The mechanism underlying the association between DM and glomerulonephritis remains to be elucidated. We herein report a case of DM associated with focal segmental glomerulosclerosis, which has not been reported previously. (Korean J Med 2012;83:828-831)
참고문헌 (8)
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